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上海药物研究所 [25]
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期刊论文 [124]
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2018 [127]
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Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Self-assembly of antigen proteins into nanowires greatly enhances the binding affinity for high-efficiency target capture
期刊论文
Acs applied materials & interfaces, 2018, 卷号: 10, 期号: 48, 页码: 41019-41025
作者:
Men, Dong
;
Zhou, Juan
;
Li, Wei
;
Wei, Cui-Hua
;
Chen, Yuan-Yuan
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  |  
浏览/下载:73/0
  |  
提交时间:2019/05/08
Self-assembly
Protein nanowire
Polyvalent interaction
Binding affinity
Sensitive immunoassay
Combinational biosynthesis and characterization of fusion proteins with tandem repeats of allophycocyanin holo-alpha subunits, and their application as bright fluorescent labels for immunofluorescence assay
期刊论文
JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2018, 卷号: 126, 期号: 6, 页码: 778-782
作者:
Chen, Huaxin
;
Jiang, Peng
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  |  
浏览/下载:224/0
  |  
提交时间:2019/05/15
Allophycocyanin
Streptavidin
Fusion protein
Fluorescence
Immunofluorescence assay
A Novel Self-Binding Composite Separator Based on Poly(tetrafluoroethylene) Coating for Li-Ion Batteries
期刊论文
POLYMERS, 2018, 卷号: 10, 期号: 12, 页码: 13
作者:
Zhang, Kaiyue
;
Xiao, Wei
;
Liu, Jianguo
;
Yan, Chuanwei
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  |  
浏览/下载:4/0
  |  
提交时间:2021/02/02
self-binding coating
poly(tetrafluoroethylene)
poly(ethylene) separator
cell performance
Li-ion battery
Potentiometric Detection of Listeria monocytogenes via a Short Antimicrobial Peptide Pair-Based Sandwich Assay
期刊论文
ANALYTICAL CHEMISTRY, 2018, 卷号: 90, 期号: 22, 页码: 13600-13606
作者:
Lv, Enguang
;
Ding, Jiawang
;
Qin, Wei
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  |  
浏览/下载:49/0
  |  
提交时间:2020/07/08
RAPID DETECTION
MAGNETIC BEADS
RECOGNITION
MEMBRANE
BACTERIOCINS
BIOSENSOR
SYSTEM
TRIFLUOROETHANOL
MECHANISMS
ELECTRODES
Different structures of berberine and five other protoberberine alkaloids that affect P-glycoprotein-mediated efflux capacity
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Zhang, Yi-Ting
;
Yu, Yu-Qi
;
Yan, Xiao-Xia
;
Wang, Wen-Jie
;
Tian, Xiao-Ting
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  |  
浏览/下载:70/0
  |  
提交时间:2019/01/08
Direct fluorescence anisotropy approach for aflatoxin B1 detection and affinity binding study by using single tetramethylrhodamine labeled aptamer
期刊论文
TALANTA, 2018, 卷号: 189, 页码: 442-450
作者:
Sun, Linlin
;
Zhao, Qiang
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浏览/下载:221/0
  |  
提交时间:2019/06/20
Aptamer
Fluorescence anisotropy
Fluorescence polarization
Aflatoxin
Affinity ligand
Binding affinity
Intramembrane ionic protein-lipid interaction regulates integrin structure and function
期刊论文
PLOS BIOLOGY, 2018, 卷号: 16, 期号: 11, 页码: 28
作者:
Chen, Jianfeng
;
Guo, Jun
;
Zhang, Youhua
;
Li, Hua
;
Chu, Huiying
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  |  
浏览/下载:39/0
  |  
提交时间:2019/06/20
Screening and expressing hiv-1 specific antibody fragments in saccharomyces cerevisiae
期刊论文
Molecular immunology, 2018, 卷号: 103, 页码: 279-285
作者:
Wang, Ying
;
Shan, Yaming
;
Gao, Xinyu
;
Gong, Rui
;
Zheng, Jun
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  |  
浏览/下载:44/0
  |  
提交时间:2019/05/08
Yeast display
Saccharomyces cerevisiae
Antibody expression
Hiv-1
Rapid re-evaluation of bioactive saponins from Paris polyphylla using affinity ultrafiltration-LC/MS with multiple drug targets
期刊论文
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2018, 卷号: 434, 页码: 87-92
作者:
Guo, Mingquan
;
Chen, Guilin
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浏览/下载:60/0
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提交时间:2018/12/29
Ultrafiltration-LC/MS
Polyphyllin
Topoisomerase I and II
Cyclooxygenase 2
Multiple drug targets
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