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浏览/检索结果: 共14条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305 作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang 收藏  |  浏览/下载：60/0  |  提交时间：2019/01/08 allosteric inhibitor  HIV-1 protease  MM-GBSA  normal mode analysis  REMD   Application of ITC-Based Characterization of Thermodynamic and Kinetic Association of Ligands With Proteins in Drug Design 期刊论文 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9 作者:  Su, Haixia;  Xu, Yechun 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 ITC  thermodynamics  kinetics  protein-ligand recognition  drug design   Dose matters: Direct killing or immunoregulatory effects of natural polysaccharides in cancer treatment 期刊论文 Carbohydrate polymers, 2018, 卷号: 195, 页码: 243-256 作者:  Pang, Guibin;  Wang, Fujun;  Zhang, Leshuai W 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Crystal structure of the Frizzled 4 receptor in a ligand-free state 期刊论文 NATURE, 2018, 卷号: 560, 期号: 7720, 页码: 666-+ 作者:  Yang, Shifan;  Wu, Yiran;  Xu, Ting-Hai;  de Waal, Parker W.;  He, Yuanzheng 收藏  |  浏览/下载：82/0  |  提交时间：2019/01/08 Peptide recognition, signaling and modulation of class B G protein-coupled receptors 期刊论文 CURRENT OPINION IN STRUCTURAL BIOLOGY, 2018, 卷号: 51, 页码: 53-60 作者:  Cao, Can;  Zhang, Haonan;  Yang, Zhenlin;  Wu, Beili 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Recent Trends and Applications of Molecular Modeling in GPCR-Ligand Recognition and Structure-Based Drug Design 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 7 作者:  Yuan, Xiaojing;  Xu, Yechun 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 GPCR  receptor-ligand recognition  drug design  molecular modeling  molecular dynamics  docking  binding affinity  binding pathway   Structural basis for signal recognition and transduction by platelet-activating-factor receptor 期刊论文 NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2018, 卷号: 25, 期号: 6, 页码: 488-+ 作者:  Cao, Can;  Tan, Qiuxiang;  Xu, Chanjuan;  He, Lingli;  Yang, Linlin 收藏  |  浏览/下载：71/0  |  提交时间：2019/01/08 Systematic profiling and comparison of the lipidomes from Panax ginseng, P. quinquefolius, and P. notoginseng by ultrahigh performance supercritical fluid chromatography/high-resolution mass spectrometry and ion mobility-derived collision cross section measurement 期刊论文 JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1548, 页码: 64-75 作者:  Shi, Xiaojian;  Yang, Wenzhi;  Qiu, Shi;  Hou, Jinjun;  Wu, Wanying 收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08 Lipidomics  Ultrahigh performance supercritical fluid chromatography  Ion mobility spectroscopy  Collision cross section  Panax  Quality control   The Molecular Mechanism Underlying Ligand Binding to the Membrane-Embedded Site of a G-Protein-Coupled Receptor 期刊论文 JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2018, 卷号: 14, 期号: 5, 页码: 2761-2770 作者:  Yuan, Xiaojing;  Raniolo, Stefano;  Limongelli, Vittorio;  Xu, Yechun 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Supramolecular glyco-poly-cyclodextrin functionalized thin-layer manganese dioxide for targeted stimulus-responsive bioimaging 期刊论文 CHEMICAL COMMUNICATIONS, 2018, 卷号: 54, 期号: 32, 页码: 4037-4040 作者:  Wang, Huan;  Liu, Ying;  Xu, Chao;  Wang, Xi;  Chen, Guo-Rong 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08