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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 发表日期：2014    专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ligand-Assisted Dual-Site Click Labeling of EGFR on Living Cells 期刊论文 chembiochem, 2014 Yang, Yi; Lin, Shixian; Lin, Wei; Chen, Peng R. 收藏  |  浏览/下载：8/0  |  提交时间：2015/11/13 click chemistry  dual-site labeling  EGFR  FRET  genetic code expansion  UNNATURAL AMINO-ACIDS  AZIDE-ALKYNE CYCLOADDITION  DIELS-ALDER REACTIONS  SUPERRESOLUTION MICROSCOPY  CELLULAR-PROTEINS  MAMMALIAN-CELLS  GENETIC-CODE  CHEMISTRY  FLUORESCENCE  RECEPTOR   Protein-Protein Interface Analysis and Hot Spots Identification for Chemical Ligand Design 期刊论文 current pharmaceutical design, 2014 Chen, Jing; Ma, Xiaomin; Yuan, Yaxia; Pei, Jianfeng; Lai, Luhua 收藏  |  浏览/下载：7/0  |  提交时间：2015/11/13 Protein-protein interface analysis  small molecular binder  binding site detection  ligandability  hot spots  Pocket V.3  SMALL-MOLECULE INHIBITORS  DRUG DISCOVERY  BINDING-SITES  CONFORMATIONAL DYNAMICS  STRUCTURAL BIOLOGY  TRANSIENT POCKETS  PREDICTION  ALLOSTERY  DRUGGABILITY  MODULATION   Structure determination of human Fas apoptosis inhibitory molecule and identification of the critical residues linking the interdomain interaction to the anti-apoptotic activity 期刊论文 acta crystallographica section d biological crystallography, 2014 Li, Guoming; Qu, Linglong; Ma, Shuaipeng; Wu, Yujie; Jin, Changwen; Zheng, Xiaofeng 收藏  |  浏览/下载：5/0  |  提交时间：2015/11/13 B-CELLS  MONOCLONAL-ANTIBODY  T-LYMPHOCYTES  LONG FORM  EXPRESSION  DEATH  ACTIVATION  RECEPTOR  LIGAND  DOMAIN   A structural mechanism for bacterial autotransporter glycosylation by a dodecameric heptosyltransferase family 期刊论文 elife, 2014 Yao, Qing; Lu, Qiuhe; Wan, Xiaobo; Song, Feng; Xu, Yue; Hu, Mo; Zamyatina, Alla; Liu, Xiaoyun; Huang, Niu; Zhu, Ping; Shao, Feng 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/13 ENTEROTOXIGENIC ESCHERICHIA-COLI  PARTICLE ELECTRON CRYOMICROSCOPY  MOLECULAR-DYNAMICS SIMULATIONS  EM STRUCTURE DETERMINATION  PROTEIN GLYCOSYLATION  SIDE-CHAIN  CLOSTRIDIUM-PASTEURIANUM  DIFFUSE ADHERENCE  GLYCOSYLTRANSFERASES  ADHESIN   Selection of DNA-Encoded Small Molecule Libraries Against Unmodified and Non-Immobilized Protein Targets 期刊论文 angewandte chemie international edition, 2014 Zhao, Peng; Chen, Zitian; Li, Yizhou; Sun, Dawei; Gao, Yuan; Huang, Yanyi; Li, Xiaoyu 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/10 DNA  DNA-encoded library  DNA-templated chemistry  drug discovery  selection  IN-VITRO SELECTION  CHEMICAL LIBRARIES  LINKED DNA  TERMINAL PROTECTION  PEPTIDE LIBRARY  COMBINATORIAL CHEMISTRY  BINDING PROTEINS  MICROARRAYS  DISCOVERY  ASSAY   Multivalent Photoaffinity Probe for Labeling Small Molecule Binding Proteins 期刊论文 生物共轭化学, 2014 Lo, Gang; Liu, Yu; Yu, Xuerong; Li, Xiaoyu 收藏  |  浏览/下载：3/0  |  提交时间：2015/11/10 DIRECTED TOSYL CHEMISTRY  COVALENT CROSS-LINKING  LIGAND-TARGET PAIRS  LIVING CELLS  IDENTIFICATION  DISCOVERY  RECEPTOR  COMPLEXES  LIBRARIES  3-TRIFLUOROMETHYL-3-PHENYLDIAZIRINE   Allosteric sites can be identified based on the residue-residue interaction energy difference 期刊论文 proteins, 2014 Ma Xiaomin; Qi Yifei; Lai Luhua 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/11 CAVITY,MM/GBSA,allosteric site identification,energy decomposition,residue-residue interaction energy   Bidirectional effect of Wnt signaling antagonist DKK1 on the modulation of anthrax toxin uptake 期刊论文 science china life sciences, 2014 Qian LiLi; Cai ChangZu; Yuan PengFei; Jeong Sun-Young; Yang XiaoZhou; Dealmeida, Venita; Ernst, James; Costa, Michael; Cohen, Stanley N.; Wei WenSheng 收藏  |  浏览/下载：5/0  |  提交时间：2015/11/10 DKK1  anthrax toxin  LRP6  TALENs  internalization  Kremen2  receptor  Wnt  CAPILLARY MORPHOGENESIS PROTEIN-2  LETHAL FACTOR  PROTECTIVE ANTIGEN  BETA-CATENIN  DICKKOPF PROTEINS  PROPELLER DOMAIN  KINASE-KINASE  LIPID RAFT  RECEPTOR  LRP6   Modes of Activation of Organometallic Iridium Complexes for Catalytic Water and C-H Oxidation 期刊论文 inorganic chemistry, 2014 Ingram, Andrew J.; Wolk, Arron B.; Flender, Cornelia; Zhang, Jialing; Johnson, Christopher J.; Hintermair, Ulrich; Crabtree, Robert H.; Johnson, Mark A.; Zare, Richard N. 收藏  |  浏览/下载：1/0  |  提交时间：2015/11/11 DESORPTION ELECTROSPRAY-IONIZATION  MASS-SPECTROMETRY  GAS-PHASE  INFRARED PHOTODISSOCIATION  PROTEIN COMPLEXES  SODIUM PERIODATE  ION  SAMPLING/IONIZATION  SPECTROSCOPY  PRECATALYSTS   Regulation of Aggregation Behavior and Neurotoxicity of Prion Neuropeptides by Platinum Complexes 期刊论文 inorganic chemistry, 2014 Wang, Xuesong; Cui, Menghan; Zhao, Cong; He, Lei; Zhu, Dengsen; Wang, Baohuai; Du, Weihong 收藏  |  浏览/下载：4/0  |  提交时间：2015/11/11 THIOFLAVIN-T-BINDING  PROTEIN-FRAGMENT  AMYLOID FIBRILS  CARBOPLATIN BINDING  THERAPEUTIC AGENTS  ALZHEIMERS-DISEASE  PEPTIDE PRP106-126  RESIDUES 106-126  CELL-DEATH  CISPLATIN