Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents | |
Yevglevskis M.; Nathubhai A.; Wadda K.; Lee G.L.; Al-Rawi S.; Jiao T.; Mitchell P.J.; James T.D.; 等 更多 | |
刊名 | Bioorganic Chemistry |
2019 | |
卷号 | 92 |
关键词 | Branched-chain fatty acid metabolism Castrate-resistant prostate cancer (CRPC) Drug lipophilicity Enzyme inhibitors Ibuprofen Mixed competitive inhibition Rational drug design Structure-activity relationships α-Methylacyl-CoA racemase (AMACR, P504S) |
DOI | 10.1016/j.bioorg.2019.103263 |
URL标识 | 查看原文 |
公开日期 | [db:dc_date_available] |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/4552898 |
专题 | 山东大学 |
作者单位 | 1.Drug & Target Discovery, Department of Pharmacy & Pharmacology, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom 2.[ N |
推荐引用方式 GB/T 7714 | Yevglevskis M.,Nathubhai A.,Wadda K.,et al. Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents[J]. Bioorganic Chemistry,2019,92. |
APA | Yevglevskis M..,Nathubhai A..,Wadda K..,Lee G.L..,Al-Rawi S..,...&等 更多.(2019).Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents.Bioorganic Chemistry,92. |
MLA | Yevglevskis M.,et al."Novel 2-arylthiopropanoyl-CoA inhibitors of α-methylacyl-CoA racemase 1A (AMACR; P504S) as potential anti-prostate cancer agents".Bioorganic Chemistry 92(2019). |
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