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科研机构
湖南中医药大学 [15]
内容类型
期刊论文 [15]
发表日期
2019 [3]
2018 [3]
2017 [4]
2016 [4]
2015 [1]
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专题:湖南中医药大学
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TLR4 deficiency has a protective effect in the MPTP/probenecid mouse model of Parkinson's disease.
期刊论文
Acta Pharmacologica Sinica, 2019
作者:
Shao, Qian-Hang
;
Chen, Ying
;
Li, Fang-Fang
;
Wang, Shuo
;
Zhang, Xiao-Ling
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
MPTP/probenecid mouse model
NF-kappaB
Parkinson's disease
Toll-like receptor 4
glial activation
neuroinflammation
oxidative stress
alpha-synuclein
Awareness and current knowledge of Parkinson's disease: a neurodegenerative disorder.
期刊论文
International Journal of Neuroscience, 2019, 卷号: 129, 期号: 1, 页码: 55-93
作者:
Khan, Asmat Ullah
;
Akram, Muhammad
;
Daniyal, Muhammad
;
Zainab, Rida*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/27
Parkinson's disease
dopaminergic pathways
motor system
neostriatum
substantia nigra pars compacta
The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in Parkinson's disease.
期刊论文
International immunopharmacology, 2019, 卷号: 67, 页码: 458-464
作者:
Wang, Shuo
;
Yuan, Yu-He*
;
Chen, Nai-Hong*
;
Wang, Hong-Bo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
NLRP3 inflammasome
Neuroinflammation
Parkinson's disease
Pyroptosis
NLRP3 inflammasome activation in the thymus of MPTP-induced Parkinsonian mouse model
期刊论文
Toxicology Letters, 2018, 卷号: 288, 页码: 1-8
作者:
Wen, Lu
;
Zhang, Qiu-Shuang
;
Heng, Yang
;
Chen, Ying
;
Wang, Shuo
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/27
Inflammasome
MPTP
NLRP3
Parkinson's disease
Thymus
alpha-Synuclein
Prion-like propagation of α-synuclein in the gut-brain axis
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 341-346
作者:
Chen, Ying
;
Shao, Qianhang
;
Yuan, Yu-He*
;
Chen, Nai-Hong*
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
CNS
central nervous system
DA
dopamine
DMV
dorsal motor nucleus of the vagus
ENS
enteric nervous system
GI
gastrointestinal
IL-1
interleukin-1
LBs
Lewy bodies
LPS
lipopolysaccharide
LAG3
lymphocyte-activation gene 3
MPTP
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
P301L
mutant Tau
PD
Parkinson's disease
PNS
peripheral nervous system
ROS
reactive oxygen species
SCFA
short chain fatty acids
SN
substantia nigra
TH
Tyrosine hydroxylase
TLR 2
Toll-like receptor 2
TNTs
tunneling nanotubes
α-synuclein
Prion-like
Enteric nervous system
Gut-brain axis
Non-motor symptom
Parkinson’s disease
Da-Bu-Yin-Wan Improves the Ameliorative Effect of DJ-1 on Mitochondrial Dysfunction Through Augmenting the Akt Phosphorylation in a Cellular Model of Parkinson's Disease
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 期号: OCT, 页码: 1206
作者:
Zhang, Yi*
;
Gong, Xiao-Gang
;
Sun, Hong-Mei*
;
Guo, Zhen-Yu
;
Hu, Jing-Hong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
Da-Bu-Yin-Wan
Parkinson's disease
DJ-1
Akt
mitochondrial function
DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult
期刊论文
Toxicology Letters, 2017, 卷号: 271, 期号: Volume 271, 页码: 74-83
作者:
Zhang, Xiao-Ling
;
Yuan, Yu-He
;
Shao, Qian-Hang
;
Wang, Zhen-Zhen
;
Zhu, Cheng-Gen
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
8-OHdG
8-hydroxygluanine
ARE
antioxidant response element
GSK3β
glycogen synthase kinase 3β
HO-1
hemeoxygenase-1
LDH
lactate dehydrogenase
MDA
malondialdehyde
NQO1
NADPH quinone oxidoreductase 1
Nrf2
nuclear factor erythroid 2-related factor
PI3K
phosphoinositide-3-kinase
PD
Parkinson’s disease
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TCMs
traditional Chinese medicines
20C
Parkinson’s disease (PD)
DJ-1
Akt
Oxidative stress
Nuclear factor erythroid 2-related factor (Nrf2)
Amyloidogenic proteins associated with neurodegenerative diseases activate the NLRP3 inflammasome
期刊论文
International Immunopharmacology, 2017, 卷号: 49, 页码: 155-160
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Yang, Peng-fei
;
Yuan, Yu-he*
;
Chen, Nai-hong*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
AD
Alzheimer's disease
ANSC
adult neural stem cell
Aβ
amyloid-β protein
CNS
central nervous system
DAMPs
danger-associated molecular patterns
IL-1
interleukin-1
LBs
Lewy bodies
NFTs
neurofibrillary tangles
NLRs
NOD-like receptors
PAMPs
pathogen-associated molecular patterns
PD
Parkinson's disease
PRRs
pattern recognition receptors
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TLRs
toll-like receptors
α-Synuclein
Amyloid-β
Inflammation
NLRP3 inflammasome
Neurodegenerative disease
Reassessment of subacute MPTP-treated mice as animal model of Parkinson's disease
期刊论文
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 10, 页码: 1317-1328
作者:
Zhang, Qiu-shuang
;
Heng, Yang
;
Mou, Zheng
;
Huang, Ju-yang
;
Yuan, Yu-he*
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/27
Parkinson's disease
MPTP model
selegiline
pramipexole
medopar
behavioral compensation
astrocytes
a-synuclein
blood brain barrier
myelin sheath
Pathological alpha-synuclein exacerbates the progression of Parkinson's disease through microglial activation.
期刊论文
Toxicology Letters, 2017, 卷号: 265, 页码: 30-37
作者:
Zhang, Qiu-Shuang
;
Heng, Yang
;
Yuan, Yu-He*
;
Chen, Nai-Hong*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
Inflammation
Microglia
Parkinson's disease
alpha-synuclein
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