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科研机构
上海药物研究所 [23]
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期刊论文 [22]
会议论文 [1]
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2021 [3]
2019 [1]
2018 [2]
2017 [1]
2016 [1]
2015 [2]
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Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel alpha-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 17
作者:
Xie, Hong-Xu
;
Zhang, Juan
;
Li, Yue
;
Zhang, Jin-He
;
Liu, Shan-Kui
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/11/04
Tetrahydrobenzo[b]thiophen-2-yl)urea
alpha-Glucosidase inhibitors
Non-competitive inhibitor
Molecular docking
Anti-hyperglycaemic activity
Type 2 diabetes
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:
Lan, Xiao-fang
;
Olaleye, Olajide E.
;
Lu, Jun-lan
;
Yang, Wei
;
Du, Fei-fei
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  |  
浏览/下载:79/0
  |  
提交时间:2021/06/11
LianhuaQingwen
glycyrrhetic acid
24-hydroxyglycyrrhetic acid
Gancao-induced pseudoaldosteronism
licorice-induced pseudoaldosteronism
11β
-hydroxysteroid dehydrogenase 2
COVID-19
colonic microbiota
Discovery of New alpha-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 9
作者:
Liu, Shan-Kui
;
Hao, Haifang
;
Bian, Yuan
;
Ge, Yong-Xi
;
Lu, Shengyuan
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  |  
浏览/下载:59/0
  |  
提交时间:2021/05/24
α
-glycosidase
virtual screening
cytotoxicity
type 2 diabetes
molecular docking
Total Synthesis of a Hyperbranched N-Linked Hexasaccharide Attached to ATCV-1 Major Capsid Protein without Precedent
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2019, 卷号: 37, 期号: 1, 页码: 42-48
作者:
Wang, Yong-Shi
;
Wu, Yong
;
Xiong, De-Cai
;
Ye, Xin-Shan
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  |  
浏览/下载:72/0
  |  
提交时间:2019/01/08
N-glycan
ATCV-1
one-pot
glycosylation
total synthesis
carbohydrates
Facilitating Anti-Cancer Combinatorial Drug Discovery by Targeting Epistatic Disease Genes
期刊论文
Molecules (Basel, Switzerland), 2018, 卷号: 23, 期号: 4
作者:
Quan, Yuan
;
Liu, Meng-Yuan
;
Liu, Ye-Mao
;
Zhu, Li-Da
;
Wu, Yu-Shan
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  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Potential hypoglycemic effect of acetophenones from the root bark of Cynanchum wilfordii
期刊论文
Natural product research, 2018, 页码: 1-8
作者:
Jiang, Hao-Wen
;
Gu, Shan-Shan
;
Cao, Lei
;
Jiang, Sheng-Shi
;
Lin, Jing
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  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials
期刊论文
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:
Yuan, Bo
;
Ye, Na
;
Song, Shan-Shan
;
Wang, Yu-Ting
;
Song, Zilan
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  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Homologous recombination repair defects
Olaparib
Growth inhibition
Patient-derived xenografts
Pharmacokinetics
Development of FTIR fingerprint for identification of armand clematis stem (Chuanmutong) and related herbs
期刊论文
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, 卷号: 41, 期号: 8, 页码: 1485-1492
作者:
Gao, Shan-Shan
;
Li, Jian-Rui
;
Wu, Fang-Bin
;
Wei, Xue-Min
;
Bian, Jin-Hui
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Terpenoids and Steroids from Euphorbia hypericifolia
期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2015, 卷号: 10, 期号: 12, 页码: 2049-2052
作者:
Zhao, Jin-Xin
;
Shi, Shan-Shan
;
Sheng, Li
;
Li, Jia
;
Yue, Jian-Min
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Euphorbia hypericifolia
Triterpenoid
Steroid
PTP1B inhibitor
Bioactive sesquiterpene quinols and quinones from the marine sponge Dysidea avara
期刊论文
RSC ADVANCES, 2015, 卷号: 5, 期号: 106, 页码: 87730-87738
作者:
Jiao, Wei-Hua
;
Xu, Ting-Ting
;
Gu, Bin-Bin
;
Shi, Guo-Hua
;
Zhu, Yan
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  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
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