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科研机构
上海药物研究所 [22]
内容类型
期刊论文 [22]
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2021 [3]
2020 [1]
2018 [2]
2017 [1]
2016 [1]
2015 [3]
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New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury
期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 11, 页码: 17
作者:
Wu, Yong-Mei
;
Shi, Qing
;
Zhu, Peng-Fei
;
Ma, Hai-Jian
;
Cui, Shi-Chao
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/12/16
acute kidney injury
IKK/NF-kappa B
inflammation
macrophage
PI3K/PDK1/Akt
rhodomeroterpene
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 19, 页码: 10972-10983
作者:
Ma, Yuqin
;
Luo, Qichao
;
Fu, Jie
;
Che, Yanxin
;
Guo, Fei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/05/24
Dictyoptesterols A-C, Delta(22)-24-oxo cholestane-type sterols with potent PTP1B inhibitory activity from the brown alga Dictyopteris undulata Holmes
期刊论文
FITOTERAPIA, 2018, 卷号: 130, 页码: 241-246
作者:
Yang, Fei
;
Zhang, Liang-Wei
;
Feng, Mei-Tang
;
Liu, Ai-Hong
;
Li, Jia
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Dictyotaceae
Dictyopteris undulate
Cholestane-type sterols
Dictyoptesterols A-C
Protein tyrosine phosphatase-1B inhibitors
Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity
期刊论文
EBioMedicine, 2018, 卷号: 34, 页码: 201-213
作者:
Fan, Hui-Ran
;
Du, Wei-Feng
;
Zhu, Tao
;
Wu, Yan-Jiao
;
Liu, Yan-Mei
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Low molecular weight xanthan gum for treating osteoarthritis
期刊论文
CARBOHYDRATE POLYMERS, 2017, 卷号: 164, 页码: 386-395
作者:
Han, Guanying
;
Chen, Qixin
;
Liu, Fei
;
Cui, Zan
;
Shao, Huarong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Xanthan gum
Low molecular weight
Sodium hyaluronate
Osteoarthritis
Pharmacokinetics and disposition of monoterpene glycosides derived from Paeonia lactiflora roots (Chishao) after intravenous dosing of antiseptic XueBiJing injection in human subjects and rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 4, 页码: 530-544
作者:
Cheng, Chen
;
Lin, Jia-zhen
;
Li, Li
;
Yang, Jun-ling
;
Jia, Wei-wei
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
herbal injection
XueBiJing
Paeonia lactiflora roots
Chishao
monoterpene glycosides
paeoniflorin
pharmacokinetics
disposition
Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization
期刊论文
MOLECULES, 2015, 卷号: 20, 期号: 6, 页码: 10342-10359
作者:
Yan, Wenzhong
;
Qing, Jie
;
Mei, Hanbing
;
Mao, Fei
;
Huang, Jin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
CypA
small molecule inhibitor
anti-HCV
O-acylation
Methylation and its role in the disposition of tanshinol, a cardiovascular carboxylic catechol from Salvia miltiorrhiza roots (Danshen)
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 5, 页码: 627-643
作者:
Tian, Dan-dan
;
Jia, Wei-wei
;
Liu, Xin-wei
;
Wang, Dan-dan
;
Liu, Jun-hua
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
tanshinol
methylation
catechol-O-methyltransferase
herb-drug interaction
Salvia miltiorrhiza roots
Danshen
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