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科研机构
上海药物研究所 [64]
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期刊论文 [63]
会议论文 [1]
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2021 [1]
2020 [2]
2019 [1]
2018 [5]
2017 [5]
2016 [8]
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Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:
Yang, Gui-Xiang
;
Sun, Jia-Min
;
Zheng, Lu-Lu
;
Zhang, Li
;
Li, Jie
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/06/11
Vascular dementia
Diosgenin
Antioxidant
Anti-cholinesterase
Multi-target-directed ligands
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:
Dong, Liang-qing
;
Peng, Li-hua
;
Ma, Li-jie
;
Liu, Dong-bing
;
Zhang, Shu
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  |  
浏览/下载:65/0
  |  
提交时间:2020/07/01
Hepatocellular carcinoma
Tumor heterogeneity
Tumor microenvironment
Immunoediting
Neoantigen
Quantitative Proteomics Reveals the Protective Effects of Huangqi Decoction Against Acute Cholestatic Liver Injury by Inhibiting the NF-kappa B/IL-6/STAT3 Signaling Pathway
期刊论文
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 2, 页码: 677-687
作者:
Wu, Jia-Sheng
;
Liu, Qian
;
Fang, Shan-Hua
;
Liu, Xing
;
Zheng, Min
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
intrahepatic cholestasis
Huangqi decoction
proteomics
NF-kappa B
IL-6
STAT3
Deficiency of beta-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases
期刊论文
JOURNAL OF IMMUNOLOGY, 2019, 卷号: 202, 期号: 2, 页码: 407-420
作者:
Cai, Yingying
;
Yang, Cuixia
;
Yu, Xiaohan
;
Qian, Jie
;
Dai, Min
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Deficiency of β-Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases
期刊论文
Journal of immunology (Baltimore, Md. : 1950), 2018
作者:
Cai, Yingying
;
Yang, Cuixia
;
Yu, Xiaohan
;
Qian, Jie
;
Dai, Min
收藏
  |  
浏览/下载:149/0
  |  
提交时间:2019/01/08
Identification of recurrent USP48 and BRAF mutations in Cushing's disease
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:
Chen, Jianhua
;
Jian, Xuemin
;
Deng, Siyu
;
Ma, Zengyi
;
Shou, Xuefei
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  |  
浏览/下载:118/0
  |  
提交时间:2019/01/08
Discovery and structure-activity relationships study of thieno[2,3-b] pyridine analogues as hepatic gluconeogenesis inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 307-317
作者:
Ma, Fei
;
Liu, Jian
;
Zhou, Tingting
;
Lei, Min
;
Chen, Jing
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  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
Thienol2,3-b]pyridine derivatives
Structure-activity relationships (SARs)
Hepatic gluconeogenesis
Type 2 diabetes mellitus (T2DM)
Bioequivalence of Oral Formulations of Anastrozole in Healthy Chinese Male Volunteers: A Randomized, Single-Dose, Two-Period, Two-Sequence Crossover Study
期刊论文
Clinical pharmacology in drug development, 2018
作者:
Chen, Jiangying
;
Zhuang, Jialang
;
Wu, Jingguo
;
Chen, Xiaoyan
;
Wang, Xueding
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  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-alpha/IFN-gamma-induced inflammatory response in keratinocytes and T cell-derived IL-17
期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 页码: 443-452
作者:
Lin, Ze-Min
;
Ma, Meng
;
Li, Heng
;
Qi, Qing
;
Liu, Yu-Ting
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
Reversible S-adenosyl-L-homocysteine
hydrolase inhibitor
Keratinocyte
Inflammation
Interleukin-17
Imiquimod
Psoriasis
Chicken bile powder protects against α-naphthylisothiocyanate-induced cholestatic liver injury in mice
期刊论文
Oncotarget, 2017, 卷号: 8, 期号: 57, 页码: 97137-97152
作者:
Li, Yi-Fei
;
Wu, Jia-Sheng
;
Li, Yuan-Yuan
;
Dai, Yan
;
Zheng, Min
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
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