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科研机构
上海药物研究所 [36]
内容类型
期刊论文 [34]
会议论文 [2]
发表日期
2021 [6]
2020 [5]
2019 [3]
2018 [2]
2017 [1]
2015 [3]
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Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
nonalcoholic steatohepatitis
inflammation
histone deacetylase inhibitor
givinostat
epigenetics
Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation
期刊论文
MOLECULAR MEDICINE REPORTS, 2021, 卷号: 23, 期号: 5, 页码: 12
作者:
Huang, He-Ming
;
Zhou, Xiao-Ru
;
Liu, Yan-Jun
;
Fan, Shi-Jie
;
Liao, Li-Ping
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/05/24
liver fibrosis
hepatic stellate cell
histone deacetylase inhibitor
epigenetics
givinostat
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Li, Wen
;
Liao, Li-ping
;
Song, Ning
;
Liu, Yan-jun
;
Ding, Yi-luan
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/06/11
glyceraldehyde 3-phosphate dehydrogenase
1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose
hydrogen deuterium exchange mass spectrometry
reversible inhibitor
glycolysis
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Li, Wen
;
Liao, Li-ping
;
Song, Ning
;
Liu, Yan-jun
;
Ding, Yi-luan
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/06/11
glyceraldehyde 3-phosphate dehydrogenase
1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose
hydrogen deuterium exchange mass spectrometry
reversible inhibitor
glycolysis
Protective Effects of 28-O-Cafeoyl Betulin (B-CA) on the Cerebral Cortex of Ischemic Rats Revealed by a NMR-Based Metabolomics Analysis (vol 89, pg 631, 2020)
期刊论文
NEUROCHEMICAL RESEARCH, 2021, 页码: 2
作者:
Liu, Xia
;
Ruan, Zhi
;
Shao, Xing-cheng
;
Feng, Hong-xuan
;
Wu, Lei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Protective Effects of 28-O-Caffeoyl Betulin (B-CA) on the Cerebral Cortex of Ischemic Rats Revealed by a NMR-Based Metabolomics Analysis
期刊论文
NEUROCHEMICAL RESEARCH, 2021, 页码: 13
作者:
Liu, Xia
;
Ruan, Zhi
;
Shao, Xing-cheng
;
Feng, Hong-xuan
;
Wu, Lei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Cerebral ischemia–
reperfusion
28-O-caffeoyl betulin
Neuroprotection
Metabolomics
NMR
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:
Li, Junyou
;
Liu, Mengqi
;
Li, Yazhou
;
Sun, Dan-dan
;
Shu, Zhihao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Short-term exposure to ZnO/MCB persistent free radical particles causes mouse lung lesions via inflammatory reactions and apoptosis pathways
期刊论文
ENVIRONMENTAL POLLUTION, 2020, 卷号: 261, 页码: 8
作者:
Zhang, Xing
;
Gu, Wenyi
;
Ma, Zhongliang
;
Liu, Yun
;
Ru, Hongbo
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Environmentally persistent free radicals
Lung cells and tissues
Oxidative stress
Inflammatory
Apoptosis
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors
期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:
Li, Huiping
;
Liu, Rongrui
;
Shao, Bin
;
Ran, Ran
;
Song, Guohong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Phase I
PARP inhibitor (fluzoparib)
solid tumor
pharmacokinetics
safety
antitumor activity
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
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