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科研机构
上海药物研究所 [11]
内容类型
期刊论文 [11]
发表日期
2021 [2]
2019 [2]
2018 [2]
2017 [1]
2016 [1]
2015 [1]
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专题:上海药物研究所
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Structural insights into the activation of human calcium-sensing receptor
期刊论文
ELIFE, 2021, 卷号: 10, 页码: 24
作者:
Chen, Xiaochen
;
Wang, Lu
;
Cui, Qianqian
;
Ding, Zhanyu
;
Han, Li
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/11/04
G-protein-coupled receptor
calcium-sensing receptor
cryo-electron microscopy
calcium ions
nanobody
CaSR
GPCR
cryo-EM
None
Systematic investigation on the anti-rheumatoid arthritis material basis and mechanism of Juan Bi Tang. Part 1: Integrating metabolic profiles and network pharmacology
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 202, 页码: 11
作者:
Li, Jiajia
;
Li, Lei
;
Wang, Yangyang
;
Zhao, Yuxuan
;
Hu, Pei
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/08/17
Juanbi-Tang (JBT)
Rheumatoid arthritis (RA)
Metabolites
Mass
Network pharmacology
Molecular docking
Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
期刊论文
PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11
作者:
Wang Yuwei
;
Tang Chunping
;
Yao Sheng
;
Lai Huanling
;
Li Runze
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
Natural product
Croton tiglium
Protein kinase C
Molecular modelling
Structural insights into a novel Ca2+-independent PL-6 alginate lyase from Vibrio OU02 identify the possible subsites responsible for product distribution
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2019, 卷号: 1863, 期号: 7, 页码: 1167-1176
作者:
Lyu, Qianqian
;
Zhang, Keke
;
Shi, Yanhong
;
Li, Weihua
;
Diao, Xiaotong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Alginate lyase
PL-6
Catalytic mechanism
X-ray crystallography
Product distribution
Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 428-441
作者:
Zhang, Qiumeng
;
Shen, Qianqian
;
Gao, Lixin
;
Tong, Linjiang
;
Li, Jia
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Aurora A
Aurora B
KDR
Multi-targeted
Anticancer
Heterocyclic
A series of camptothecin prodrugs exhibit HDAC inhibition activity
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 16, 页码: 4706-4715
作者:
Zhu, Qiwen
;
Yu, Xumeng
;
Shen, Qianqian
;
Zhang, Qiumeng
;
Su, Mingbo
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Camptothecin
HDAC
SAHA
Prodrug
Lowered fasting chenodeoxycholic acid correlated with the decrease of fibroblast growth factor 19 in Chinese subjects with impaired fasting glucose
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Zhang, Jing
;
Li, Huating
;
Zhou, Hu
;
Fang, Li
;
Xu, Jingjing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Polydopamine-Functionalized Graphene Oxide Loaded with Gold Nanostars and Doxorubicin for Combined Photothermal and Chemotherapy of Metastatic Breast Cancer
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2016, 卷号: 5, 期号: 17, 页码: 2227-2236
作者:
Wang, Fengyang
;
Sun, Qianqian
;
Feng, Bing
;
Xu, Zhiai
;
Zhang, Junying
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
chemotherapy
dopamine
gold nanostar
graphene oxide
photothermal therapy
Near infrared light-actuated gold nanorods with cisplatin-polypeptide wrapping for targeted therapy of triple negative breast cancer
期刊论文
NANOSCALE, 2015, 卷号: 7, 期号: 36, 页码: 14854-14864
作者:
Feng, Bing
;
Xu, Zhiai
;
Zhou, Fangyuan
;
Yu, Haijun
;
Sun, Qianqian
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR(8) Peptide/p53 DNA for Cocktail Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2013, 卷号: 23, 期号: 48, 页码: 6068-6075
作者:
Wang, Huiyuan
;
Guo, Qianqian
;
Jiang, Yifan
;
Liu, Ergang
;
Zhao, Yongxing
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
apoptotic peptides
cell-penetrating peptides
p53 gene
cocktail therapies
doxorubicin
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