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科研机构
上海药物研究所 [44]
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期刊论文 [44]
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2021 [5]
2020 [5]
2019 [2]
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DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing
期刊论文
CELL METABOLISM, 2021, 卷号: 33, 期号: 10, 页码: 2004-+
作者:
Li, Yufeng
;
Xu, Junyu
;
Lu, Yuting
;
Bian, Hua
;
Yang, Lin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/18
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:
Lu, Tian
;
Li, Yong
;
Lu, Wenchao
;
Spitters, Twgm
;
Fang, Xueyu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/12/01
Hippo pathway
TEAD3
Covalent inhibitor
Palmitoylation inhibitor
Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis
期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 43, 页码: 26594-26606
作者:
Yu, Yang
;
Wu, Shifei
;
Zhang, Jianqing
;
Li, Jiayuan
;
Yao, Changliang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/11/04
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2021/08/17
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
收藏
  |  
浏览/下载:152/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Original Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2020, 卷号: 129, 页码: 10
作者:
Sun, Jingchao
;
Xu, Wenjie
;
Hua, Huaijie
;
Xiao, Ying
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
Angiotensin receptor-NEP inhibitor
Heart failure
Neprilysin inhibitor
Angiotensin receptor blocker
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:118/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Three new bisflavonols from the seeds of Hovenia dulcis Thunb. and their anti-RSV activities
期刊论文
FITOTERAPIA, 2020, 卷号: 143, 页码: 6
作者:
Xu, Fangfang
;
Gao, Meihua
;
Li, Hua
;
Han, Xiaodong
;
Zhang, Xiaoqi
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Hovenia dulcis Thunb.
Bisflavonol
Flavonoids
Anti-RSV activity
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:
Dong, Liang-qing
;
Peng, Li-hua
;
Ma, Li-jie
;
Liu, Dong-bing
;
Zhang, Shu
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2020/07/01
Hepatocellular carcinoma
Tumor heterogeneity
Tumor microenvironment
Immunoediting
Neoantigen
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis
期刊论文
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:
Zhang, Zi-jia
;
Wu, Wen-yong
;
Hou, Jin-jun
;
Zhang, Lin-lin
;
Li, Fei-fei
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
Lung-toxin Dispelling Formula No. 1
COVID-19
3C-like protease
Network pharmacology
Molecular docking
Meridian tropism
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