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Competitive CatSper Activators of Progesterone from Rhynchosia volubilis 期刊论文
PLANTA MEDICA, 2021, 页码: 10
作者:  Xiang, Jin;  Kang, Hang;  Li, Hong-Gang;  Shi, Yu-Long;  Zhang, Ya-Li
收藏  |  浏览/下载:44/0  |  提交时间:2021/11/04
Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 4
作者:  Xiang, Hao-Yue;  Chen, Jian-Yang;  Huan, Xia-Juan;  Chen, Yi;  Gao, Zhao-bing
收藏  |  浏览/下载:17/0  |  提交时间:2021/05/24
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
收藏  |  浏览/下载:36/0  |  提交时间:2021/05/24
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma 期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:  Dong, Liang-qing;  Peng, Li-hua;  Ma, Li-jie;  Liu, Dong-bing;  Zhang, Shu
收藏  |  浏览/下载:70/0  |  提交时间:2020/07/01
GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 46, 页码: 7133-7145
作者:  Yang, Rui;  Liu, Na;  Chen, Ling;  Jiang, Yiqun;  Shi, Ying
收藏  |  浏览/下载:52/0  |  提交时间:2020/07/01
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Gao, Ming-Zhao;  Wang, Hong-Bin;  Chen, Xiang-Ling;  Cao, Wen-Ting;  Fu, Li
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3K alpha-selective inhibitor CYH33 in breast cancer 期刊论文
CANCER LETTERS, 2018, 卷号: 433, 页码: 273-282
作者:  Liu, Xue-ling;  Xu, Yi-chao;  Wang, Yu-xiang;  Chen, Yi;  Wang, Bo-bo
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
TRPA1 channel mediates organophosphate-induced delayed neuropathy 期刊论文
CELL DISCOVERY, 2017, 卷号: 3
作者:  Ding, Qiang;  Fang, Sui;  Chen, Xueqin;  Wang, Youxin;  Li, Jian
收藏  |  浏览/下载:42/0  |  提交时间:2019/01/08
DW09849, a Selective Phosphatidylinositol 3-Kinase (PI3K) Inhibitor, Prevents PI3K Signaling and Preferentially Inhibits Proliferation of Cells Containing the Oncogenic Mutation p110 alpha (H1047R) 期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 卷号: 348, 期号: 3, 页码: 432-441
作者:  Liu, Jia-li;  Gao, Guo-rui;  Zhang, Xi;  Cao, Su-fen;  Guo, Chen-liang
收藏  |  浏览/下载:18/0  |  提交时间:2019/01/08
Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design 期刊论文
JOURNAL OF VIROLOGY, 2011, 卷号: 85, 期号: 19, 页码: 10319-10331
作者:  Lu, Guangwen;  Qi, Jianxun;  Chen, Zhujun;  Xu, Xiang;  Gao, Feng
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08


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