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科研机构
上海药物研究所 [89]
内容类型
期刊论文 [89]
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2021 [14]
2020 [9]
2019 [9]
2018 [10]
2017 [5]
2016 [5]
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Pharmacolo... [2]
Chemistry [1]
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New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Dezocine as a potent analgesic: overview of its pharmacological characterization
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Ye, Rong-Rong
;
Jiang, Shuang
;
Xu, Xu
;
Lu, Yan
;
Wang, Yu-Jun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/16
dezocine
opioid receptors
norepinephrine
serotonin transporter
postoperative pain
anesthesia
A simultaneous identification and quantification strategy for determination of sulfhydryl-containing metabolites in normal- and high-fat diet hamsters using stable isotope labeling combined with LC-MS
期刊论文
ANALYTICA CHIMICA ACTA, 2021, 卷号: 1184, 页码: 13
作者:
Chang, Lu
;
Lin, Feifei
;
Cheng, Kai
;
Li, Jiaomeng
;
Sun, Xiaochu
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2022/01/18
Sulfhydryl-containing metabolites
Stable isotope labeling
Identification
Quantification
Hyperlipidemia
Oxidative stress
HBO1 is a versatile histone acyltransferase critical for promoter histone acylations
期刊论文
NUCLEIC ACIDS RESEARCH, 2021, 卷号: 49, 期号: 14, 页码: 8037-8059
作者:
Xiao, Yanhui
;
Li, Wenjing
;
Yang, Hui
;
Pan, Lulu
;
Zhang, Liwei
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/11/04
Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket
期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:
Lu, Yan
;
Liu, Hongyue
;
Yang, Dehua
;
Zhong, Li
;
Xin, Ye
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Su, Haixia
;
Yao, Sheng
;
Zhao, Wenfeng
;
Zhang, Yumin
;
Liu, Jia
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/08/17
MALDI-MS imaging of lipids and small molecules in rat brain tissue based on graphene oxide film pre-coated matrix
期刊论文
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2021, 卷号: 464, 页码: 8
作者:
Xu, Yang
;
Deng, Yingzhi
;
Ye, Rongrong
;
Gong, Can
;
Liu, Zhaoxin
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/06/11
Single-layer graphene oxide film
Matrix-assisted laser desorption ionization-mass spectrometry imaging
Phospholipids
Pre-coated matrix
Polyisoprenylated benzophenone derivatives from Garcinia cambogia and their anti-inflammatory activities
期刊论文
FOOD & FUNCTION, 2021, 页码: 10
作者:
Feng, Zheling
;
Chen, Jiali
;
Feng, Lu
;
Chen, Cheng
;
Ye, Yang
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/08/17
Antimicrobial and Immunomodulating Activities of Two Endemic Nepeta Species and Their Major Iridoids Isolated from Natural Sources
期刊论文
PHARMACEUTICALS, 2021, 卷号: 14, 期号: 5, 页码: 22
作者:
Anicic, Neda
;
Gasic, Uros
;
Lu, Feng
;
Ciric, Ana
;
Ivanov, Marija
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/08/17
Nepeta
nepetalactone
1,5,9-epideoxyloganic acid
antimicrobial activity
antibiofilm
immunomodulatory effects
Biscaesalmins A and B from Caesalpinia minax, highly oxidized dimeric cassane diterpenoids as interleukin-1 beta inhibitors
期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 4, 页码: 1475-1479
作者:
Xu, Yunshao
;
Zhang, Tian
;
Feng, Lu
;
Feng, Zheling
;
Zhang, Qingwen
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/08/17
Caesalpinia minax
IL-1 beta
Dimeric cassane diterpenoids
NLRP3
TD-DFT
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