×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [13]
内容类型
期刊论文 [13]
发表日期
2020 [1]
2018 [3]
2017 [1]
2012 [1]
2011 [3]
2009 [2]
更多...
学科主题
Chemistry [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共13条,第1-10条
帮助
限定条件
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Discovery of New and Potent InhA Inhibitors as Antituberculosis Agents: Structure-Based Virtual Screening Validated by Biological Assays and X-ray Crystallography
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 1, 页码: 226-234
作者:
Kamsri, Pharit
;
Hanwarinroj, Chayanin
;
Phusi, Naruedon
;
Pornprom, Thimpika
;
Chayajarus, Kampanart
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors
期刊论文
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:
Cheng, Zhi-Qiang
;
Zhu, Kong-Kai
;
Zhang, Juan
;
Song, Jia-Li
;
Muehlmann, Luis Alexandre
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125
作者:
Liu, Wenwen
;
Wang, Huan
;
Li, Xiaokang
;
Xu, Yixiang
;
Zhang, Jian
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Depression
Cognitive impairment
Multitarget-directed ligand
5-HT1A agonist
5-HT reuptake inhibition
ChE inhibition
Ligand-enabled ortho-C-H olefination of phenylacetic amides with unactivated alkenes
期刊论文
CHEMICAL SCIENCE, 2018, 卷号: 9, 期号: 5, 页码: 1311-1316
作者:
Lu, Ming-Zhu
;
Chen, Xing-Rong
;
Xu, Hui
;
Dai, Hui-Xiong
;
Yu, Jin-Quan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721
作者:
Li, Xiaokang
;
Wang, Huan
;
Xu, Yixiang
;
Liu, Wenwen
;
Gong, Qi
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Alzheimer's disease
depression
multitarget-directed ligand
ChE inhibition
5-HT1A agonist
5-HT reuptake inhibition
Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 2, 页码: 958-962
作者:
Huang, Huang
;
Lu, Weiqiang
;
Li, Xi
;
Cong, Xiaoli
;
Ma, Hongmei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Falcipain-2
Dihydrofolate reductase
Dual inhibitor
Antimalarial drug
SAR
Molecular docking
Velocity-scaling optimized replica exchange molecular dynamics of proteins in a hybrid explicit/implicit solvent
期刊论文
JOURNAL OF CHEMICAL PHYSICS, 2011, 卷号: 135, 期号: 8
作者:
Wang, Jinan
;
Zhu, Weiliang
;
Li, Guohui
;
Hansmann, Ulrich H. E.
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
HL005-A new selective PPAR gamma antagonist specifically inhibits the proliferation of MCF-7
期刊论文
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2011, 卷号: 124, 期号: 3-5, 页码: 112-120
作者:
Lu, Weiqiang
;
Che, Peng
;
Zhang, Yanyan
;
Li, Honglin
;
Zou, Shien
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Peroxisome proliferator-activated receptor-gamma
Selective antagonist
Anticancer
Apoptosis
Organocatalytic enantioselective beta-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions
期刊论文
NATURE COMMUNICATIONS, 2011, 卷号: 2
作者:
Zhang, Shi-Lei
;
Xie, He-Xin
;
Zhu, Jin
;
Li, Hao
;
Zhang, Xin-Shuai
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
©版权所有 ©2017 CSpace - Powered by
CSpace