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浏览/检索结果: 共28条，第1-10条 帮助 限定条件 发表日期：2021    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14 作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia 收藏  |  浏览/下载：65/0  |  提交时间：2021/11/04 Type 2 diabetes mellitus  Dual FABP4/5 inhibitors  Anti-lipolytic and anti-inflammatory effects  Metabolic stability  Anti-diabetic activities   Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635 作者:  Wu, Aihua;  Chen, Yingzhi;  Wang, Hairui;  Chang, Ya;  Zhang, Meng 收藏  |  浏览/下载：27/0  |  提交时间：2022/01/18 Trichosanthin  Legumain  TRP2  Transcutaneous immunization  Adjuvant  Cancer vaccine  Protein engineering   Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13 作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun 收藏  |  浏览/下载：32/0  |  提交时间：2021/12/01 2,5-diphenyl-1,3,4-oxadiazole derivatives  SHP2  Inhibitors  Structure-activity relationships (SAR)   Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125 作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao 收藏  |  浏览/下载：37/0  |  提交时间：2022/01/04 Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin 期刊论文 GLYCOCONJUGATE JOURNAL, 2021, 页码: 11 作者:  Zeng, Jiaxin;  Meng, Yuan;  Chen, Shi-Yi;  Zhao, Gaofeng;  Wang, Lianchun 收藏  |  浏览/下载：53/0  |  提交时间：2021/12/01 Furin  Heparan sulfate  Heparin  Virus infection  Carbohydrate-protein interaction   Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment 期刊论文 NANO TODAY, 2021, 卷号: 40, 页码: 14 作者:  Tang, Yisi;  Fan, Wufa;  Chen, Guihua;  Zhang, Meng;  Tang, Xueping 收藏  |  浏览/下载：43/0  |  提交时间：2021/12/01 Cancer therapeutic vaccine  Legumain  Tumor-associated macrophage  Trichosanthin  Liposome  Adjuvant   Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy 期刊论文 EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8 作者:  Xiao, Meng-Chao;  Qian, Hui;  Huang, Chen-Kai;  Zheng, Bai-Nan;  Yan, Fang-Zhi 收藏  |  浏览/下载：51/0  |  提交时间：2021/11/04 Imatinib  Autophagy  Hepatocarcinoma  Sorafenib  Synergetic effect   Polyprenylated acylphloroglucinol meroterpenoids with PTP1B inhibition from Hypericum forrestii 期刊论文 FITOTERAPIA, 2021, 卷号: 153, 页码: 5 作者:  Zong, Jian-Fa;  Zhang, Meng-Meng;  Zhou, Yu-Bo;  Li, Jia;  Hou, Ai-Jun 收藏  |  浏览/下载：67/0  |  提交时间：2021/11/04 Hypericum forrestii (Chittenden) N Robson  Clusiaceae  Acylphloroglucinol meroterpenoid  Hyperiforins A-C  Protein tyrosine phosphatase 1B   NGPF2 triggers synaptic scaling up through ALK-LIMK-cofilin-mediated mechanisms 期刊论文 CELL REPORTS, 2021, 卷号: 36, 期号: 7, 页码: 20 作者:  Zhou, Zikai;  He, Guiqin;  Zhang, Xiaoyun;  Lv, Xin;  Zhang, Xiaolin 收藏  |  浏览/下载：68/0  |  提交时间：2021/11/04 Design, Synthesis, and Biological Evaluation of Novel Pyrimido[4,5-b]indole Derivatives Against Gram-Negative Multidrug-Resistant Pathogens 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8644-8665 作者:  Kong, Qidi;  Pan, Wei;  Xu, Heng;  Xue, Yaru;  Guo, Bin 收藏  |  浏览/下载：39/0  |  提交时间：2021/08/17