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浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation 期刊论文 BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69 作者:  Lv, Jianlu;  Wang, Wei;  Zhu, Xialin;  Xu, Xiaoju;  Yan, Qiuying 收藏  |  浏览/下载：33/0  |  提交时间：2020/12/21 Alzheimer'sdisease  Microglia  AMPK alpha 1  DW14006  Phagocytosis  Neuro-inflammation   A phase II randomized trial of sodium oligomannate in Alzheimer's dementia 期刊论文 ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10 作者:  Wang, Tao;  Kuang, Weihong;  Chen, Wei;  Xu, Wenwei;  Zhang, Liming 收藏  |  浏览/下载：65/0  |  提交时间：2020/12/21 Sodium oligomannate  Efficacy  Safety  Alzheimer's disease  Clinical trial   A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2020, 卷号: 12, 期号: 1 作者:  Wang,Tao;  Kuang,Weihong;  Chen,Wei;  Xu,Wenwei;  Zhang,Liming 收藏  |  浏览/下载：74/0  |  提交时间：2020/12/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yang, Fang-ming;  Fan, Di;  Yang, Xiao-qian;  Zhu, Feng-hua;  Shao, Mei-juan 收藏  |  浏览/下载：28/0  |  提交时间：2020/12/24 dry eye disease  artemisinin derivative  beta-aminoarteether maleate  inflammation  macrophages  TLR4  inflammasome   AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8 作者:  Sun, Shui-mei;  Xie, Zhi-fu;  Zhang, Yang-ming;  Zhang, Xin-wen;  Zhou, Chen-dong 收藏  |  浏览/下载：28/0  |  提交时间：2020/12/24 adenosine 5 '-monophosphate-activated protein kinase  AMPK activator  C24  liver  triglycerides  cholesterol  VLDL  hypolipidemic drug  metabolic syndrome   Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10 作者:  Yu, Yan-yan;  Cui, Shi-chao;  Zheng, Tian-nan;  Ma, Hai-jian;  Xie, Zhi-fu 收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24 insulin resistance  sarsasapogenin  adipose tissue inflammation  macrophage-adipocyte crosstalk  IKK/NF-kappa B  JNK   Safety, Clinical Activity, and Pharmacokinetics of Al flutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation 期刊论文 JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15, 期号: 6, 页码: 1015-1026 作者:  Shi, Yuankai;  Zhang, Shucai;  Hu, Xingsheng;  Feng, Jifeng;  Ma, Zhiyong 收藏  |  浏览/下载：42/0  |  提交时间：2020/12/24 Alflutinib  NSCLC  EGFR T790M mutation  Efficacy  Safety   Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma 期刊论文 JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908 作者:  Dong, Liang-qing;  Peng, Li-hua;  Ma, Li-jie;  Liu, Dong-bing;  Zhang, Shu 收藏  |  浏览/下载：70/0  |  提交时间：2020/07/01 Hepatocellular carcinoma  Tumor heterogeneity  Tumor microenvironment  Immunoediting  Neoantigen   Hyperprins A and B, Two Complex Meroterpenoids from Hypericum przewalskii 期刊论文 ORGANIC LETTERS, 2020, 卷号: 22, 期号: 7, 页码: 2797-2800 作者:  Zong, Jian-Fa;  Hu, Zhu;  Shao, Ying-Ying;  Shi, Qing;  Zhang, Meng-Meng 收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14 作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 lnterleukin-1 receptor associated kinase 4  Imidazol1,2-6]pyridazine  Diffuse large B-cell lymphoma  Drug design  Antitumor agents