QQ客服 官方微博 反馈留言

浏览/检索结果: 共22条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 101-112 作者:  Ji, Yue-Yang;  Lin, Sen-Dong;  Wang, Yu-Jie;  Su, Ming-Bo;  Zhang, Wei 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Tranylcypromine  LSD1  Stereoselective cyclopropanation  Chiral synthesis  MAO-A  MAO-B   Chicken bile powder protects against α-naphthylisothiocyanate-induced cholestatic liver injury in mice 期刊论文 Oncotarget, 2017, 卷号: 8, 期号: 57, 页码: 97137-97152 作者:  Li, Yi-Fei;  Wu, Jia-Sheng;  Li, Yuan-Yuan;  Dai, Yan;  Zheng, Min 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Chemical constituents from hypoglycemic active part of Plantaginis Semen 期刊论文 Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, 卷号: 42, 期号: 21, 页码: 4150-4153 作者:  Peng, Qing-Hua;  Han, Zhu-Zhen;  Tong, Ren-Chao;  Hu, Xin-Quan;  Yang, Qi-Ming 收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532 作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   Synthesis and antitumor activity of a series of lactone-opened camptothecin derivatives 期刊论文 Journal of Asian natural products research, 2017, 页码: 1-11 作者:  Zheng, Chao;  Li, Ming-Zong;  You, Tian-Pa;  Tang, Wei-Ping;  Lou, Li-Guang 收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression 期刊论文 NATURE COMMUNICATIONS, 2017, 卷号: 8 作者:  Ju, Junyi;  Chen, Aiping;  Deng, Yexuan;  Liu, Ming;  Wang, Ying 收藏  |  浏览/下载：48/0  |  提交时间：2019/01/08 Soluble epoxide hydrolase activation by S-nitrosation contributes to cardiac ischemia-reperfusion injury 期刊论文 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2017, 卷号: 110, 页码: 70-79 作者:  Ding, Yuzhu;  Li, Yazi;  Zhang, Xu;  He, Jinlong;  Lu, Dong 收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08 Epoxyeicosatrienoic acid  Ischemia-reperfusion  Nitric oxide  S-nitrosation  Soluble epoxide hydrolase   Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells 期刊论文 JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 7, 页码: 1981-1991 作者:  Xu, Ya-Ming;  Wijeratne, E. M. Kithsiri;  Babyak, Ashley L.;  Marks, Hanna R.;  Brooks, Alan D. 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068 作者:  Wang, Gui-min;  Wang, Xiang;  Zhu, Jian-ming;  Guo, Bin-bin;  Yang, Zhuo 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 B-Raf(V600E) inhibitor  anticancer  vemurafenib  deazapurine  fragment reassembly  molecular docking  structure-activity relationship   W2476 ameliorates beta-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1024-1037 作者:  Li, Ting;  Lin, Guang-yao;  Zhong, Li;  Zhou, Yan;  Wang, Jia 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 diabetes  glucose  TXNIP  beta-cells  W2476  high-throughput screening