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CORC

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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载：37/0  |  提交时间：2021/12/01
Cinnamtannin D1 Protects Pancreatic beta-Cells from Glucolipotoxicity-Induced Apoptosis by Enhancement of Autophagy In Vitro and In Vivo 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 卷号: 68, 期号: 45, 页码: 12617-12630
作者:  Wang, Xin-Yi;  Zhu, Bo-Rong;  Jia, Qi;  Li, Yi-Ming;  Wang, Ting
收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu
收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：22/0  |  提交时间：2020/12/21
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue
收藏  |  浏览/下载：23/0  |  提交时间：2020/12/21
Intestinal microbes derived butyrate is related to the immunomodulatory activities of Dendrobium officinale polysaccharide 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 149, 页码: 717-723
作者:  Li, Meixia;  Yue, Han;  Wang, Yeqing;  Guo, Ciliang;  Du, Zhenyun
收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01
National Institutes of Health[HG006827] 项目
项目编号: HG006827, 资助机构: National Institutes of Health, 2019-
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收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01
Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine 期刊论文
CHEMICAL SCIENCE, 2019, 卷号: 10, 期号: 31, 页码: 7407-7417
作者:  Fu, Tianran;  Liu, Liping;  Yang, Qing-Lin;  Wang, Yuxin;  Xu, Pan
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants 期刊论文
CANCER SCIENCE, 2019, 页码: 9
作者:  Gao, Mingzhao;  Zhu, Hongmei;  Fu, Li;  Li, Yun;  Bao, Xubin
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01
AG-221  IDH2  leukemia  R140Q  R172K  
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:  Duan, Zhe;  Liu, Jingqiu;  Niu, Liping;  Wang, Jun;  Feng, Mingqian
收藏  |  浏览/下载：55/0  |  提交时间：2020/07/01

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