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科研机构
上海药物研究所 [2]
中国水产科学院 [2]
厦门大学 [1]
北京大学 [1]
山东大学 [1]
武汉大学 [1]
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期刊论文 [11]
发表日期
2013 [11]
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Identification of Novel Small Molecules as Inhibitors of Hepatitis C Virus by Structure-Based Virtual Screening
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 卷号: 14, 期号: 11, 页码: 22845-22856
作者:
Li, Jing
;
Liu, Xian
;
Li, Shanshan
;
Wang, Yulan
;
Zhou, Nannan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
hepatitis C virus (HCV)
NS3
NS4A serine protease
structure-based drug design (SBDD)
virtual screening
Non-Covalent Interactions with Aromatic Rings: Current Understanding and Implications for Rational Drug Design
期刊论文
CURRENT PHARMACEUTICAL DESIGN, 2013, 卷号: 19, 期号: 36, 页码: 6522-6533
作者:
Li, Shanshan
;
Xu, Yuan
;
Shen, Qiancheng
;
Liu, Xian
;
Lu, Jing
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
pi-pi interactions
cation-pi interactions
anion-pi interactions
quantum mechanical calculations
crystallographic data mining
rational drug design
Acetylcholine esterase (AChE)
HMG-CoA reductase (HMGR)
serine protease factor Xa (fXa)
A novel acidic serine protease, ASP(NJ) inhibits proliferation, induces apoptosis and enhances chemo-susceptibility of acute promyelocytic leukemia cell
期刊论文
LEUKEMIA RESEARCH, 2013, 卷号: 37, 期号: 12
作者:
Jiang, Xue
;
Liu, Jiankai
;
Hong, Min
;
Ge, Xin
;
Bo, Qiqing
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Acidic serine protease
Fibrinolytic enzyme
NB4 cell
Apoptosis
Chemo-susceptibility
Acute promyelocytic leukemia
Human peripheral blood cells
Tailoring the pH Dependence of Human Non-pancreatic Secretory Phospholipase A(2) by Engineering Surface Charges
期刊论文
应用生物化学与生物技术, 2013
Qiu, Shunchen
;
Lai, Luhua
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2015/11/10
Phospholipase A(2)
Protein engineering
Enzyme reaction optimum pH
Catalytic mechanism
The catalytic triad mechanism
The calcium-coordinated oxyanion mechanism
GROUP-IIA
ACTIVE-SITE
CATALYTIC MECHANISM
SERINE-PROTEASE
PANCREATIC PHOSPHOLIPASE-A2
CRYSTAL-STRUCTURE
ENZYME CATALYSIS
OPTIMUM
BINDING
STABILITY
Effects of fluid shear stress on the expression of Omi/HtrA2 in human umbilical vein endothelial cells
期刊论文
http://dx.doi.org/10.3892/mmr.2012.1137, 2013
Sun, Liang-Liang
;
Zhang, Le
;
Meng, Xiang-Lan
;
Zhang, Feng
;
Zhao, Yun
;
Jin, Xin
;
赵云
;
金鑫
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/07/22
SERINE-PROTEASE
APOPTOSIS
FLOW
INHIBITOR
INDUCTION
HTRA2
Cloning and Heterologous Expression of Serine Protease SL41 Related to Biocontrol in Trichoderma harzianum
期刊论文
Journal of molecular microbiology and biotechnology: JMMB, 2013, 卷号: 23, 期号: 6, 页码: 431-439
作者:
Liu, Y.
;
Yang, Q.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/23
Antagonistic activity
Biocontrol
Expression pattern
Serine protease
SL41
Trichoderma harzianum
Molecular Basis for Auto- and Hetero-catalytic Maturation of a Thermostable Subtilase from Thermophilic Bacillus sp WF146
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 卷号: 288, 期号: 48
作者:
Zhu, Hui
;
Xu, Bi-Lin
;
Liang, Xiaoliang
;
Yang, Yi-Ran
;
Tang, Xiao-Feng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Bacteria
Enzyme Structure
Protein Processing
Protein Stability
Serine Protease
Maturation
Propeptide
Subtilase
Molecular cloning and expression analysis of chymotrypsin-like serine protease from the redclaw crayfish (Cherax quadricarinatus): A possible role in the junior and adult innate immune systems
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2013, 卷号: 34, 期号: 6, 页码: 1546-1552
作者:
Fang, Di-An[1]
;
Huang, Xian-Ming[2]
;
Zhang, Zhi-Qin[3]
;
Xu, Dong-Po[4]
;
Zhou, Yan-Feng[5]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/02
Chymotrypsin-like serine protease
Cherax quadricarinatus
The innate immune system
Purification, Properties of a Cold-adapted Protease PA-1 Isolated from Marine Pseudomonas sp.
期刊论文
JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2013, 卷号: 7, 期号: 4, 页码: 2739-2745
作者:
Wang, Fang[1]
;
Sheng, Jun[2]
;
Xu, Jiakun[3]
;
Sun, Mi[4]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/02
Pseudomonas cold-adapted
Protease isolation
Purification serine
Purification, characterization and gene cloning of Da-36, a novel serine protease from Deinagkistrodon acutus venom
期刊论文
2013, 卷号: 67, 页码: 1-11
作者:
Zheng, Ying
;
Ye, Feng-Ping
;
Wang, Jie
;
Liao, Guo-Yang
;
Zhang, Yun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/13
Deinagkistrodon acutus
Gene
Serine protease
Purification
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