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厦门大学 [4]
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期刊论文 [15]
学位论文 [2]
发表日期
2012 [17]
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A Peptide Binding to the beta-Site of APP Improves Spatial Memory and Attenuates A beta Burden in Alzheimer's Disease Transgenic Mice
期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 11, 页码: 文献号: e48540
作者:
Yang, Shi-gao
;
Wang, Shao-wei
;
Zhao, Min
;
Zhang, Ran
;
Zhou, Wei-wei
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2013/10/11
AMYLOID PRECURSOR PROTEIN
CLEAVING ENZYME-1 BACE1
LONG-TERM POTENTIATION
SINGLE-CHAIN ANTIBODY
GAMMA-SECRETASE
MOUSE MODEL
THERAPEUTIC TARGET
ALPHA-SECRETASE
CELL BIOLOGY
IN-VITRO
Appoptosin is a Novel Pro-Apoptotic Protein and Mediates Cell Death in Neurodegeneration
期刊论文
http://dx.doi.org/10.1523/JNEUROSCI.3668-12.2012, 2012
Zhang, Han
;
Zhang, Yun-wu
;
Chen, Yaomin
;
Huang, Xiumei
;
Zhou, Fangfang
;
Wang, Weiwei
;
Xian, Bo
;
Zhang, Xian
;
Masliah, Eliezer
;
Chen, Quan
;
Han, Jing-Dong J.
;
Bu, Guojun
;
Reed, John C.
;
Liao, Francesca
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2013/12/12
AMYLOID PRECURSOR PROTEIN
CENTRAL-NERVOUS-SYSTEM
ALZHEIMERS-DISEASE
INTRACELLULAR DOMAIN
HEME OXYGENASE-1
DEFICIENT MICE
ACTIVATION
FAMILY
PHOSPHORYLATION
MECHANISMS
Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing
期刊论文
2012
Zhao, Yonghao
;
Wang, Yunshu
;
Yang, Jiaye
;
Wang, Xin
;
Zhao, Yingjun
;
Zhang, Xian
;
Zhang, Yun-wu
;
张云武
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2013/03/21
beta-amyloid
beta-amyloid precursor protein
beta-site APP cleaving enzyme 1
Alzheimer's disease
Intracellular trafficking
Sorting nexin 12
Overexpression of Human Wild-Type Amyloid-beta Protein Precursor Decreases the Iron Content and Increases the Oxidative Stress of Neuroblastoma SH-SY5Y Cells
期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2012, 卷号: 30, 期号: 3, 页码: 523-530
Wan, Li
;
Nie, Guangjun
;
Zhang, Jie
;
Zhao, Baolu
;
赵保路
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2013/12/24
Alzheimer's disease
amyloid-beta protein precursor
iron deficiency
oxidative stress
Metal Metabolic Homeostasis Disruption and Early Initiation of Mechanism for Alzheimer's Disease
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2012, 卷号: 39, 期号: 8, 页码: 756-763
Zhao Baolu
;
赵保路
;
Wan Li
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2013/12/24
Alzheimer's disease (AD)
metal iron homeostasis disruption
oxidative stress
beta-amyloid (A beta)
amyloid precursor protein (APP)
iron regulatory protein (IRP)
divalent metal transporter 1 (DMT1)
natural antioxidants
An age-related axon terminal pathology around the first olfactory relay that involves amyloidogenic protein overexpression without plaque formation
期刊论文
Neuroscience, 2012, 卷号: 215, 页码: 160-173
作者:
Cai, Y
;
Xue, Z-Q
;
Zhang, X-M
;
Li, M-B
;
Wang, H
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
AD
Alzheimer’s disease
APP
β-amyloid precursor protein
Aβ
β-amyloid peptide
EPL
external plexiform layer
FAD
familial AD
GAP43
growth-associated protein 43
GCL
granule cell layer
GL
glomerular layer
MAP2
microtubule-associated protein-2
NFL
nerve fiber layer
OMP
olfactory marker protein
PBS
phosphate-buffered saline
SEZ
subependymal zone
TH
tyrosine hydroxylase
VGLUT2
vesicular glutamate transporter-2
aging
dementia
amyloidogenesis
axonal pathology
olfactory deficit
Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons
期刊论文
神经科学通报, 2012
Yang, Bin
;
Sun, Xiaqin
;
Lashuel, Hilal
;
Zhang, Yan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/11
amyloid
reactive oxidative species
APP/ PS1
aggregation
toxicity
ALZHEIMERS-DISEASE
TRANSGENIC MICE
BETA-PEPTIDE
A-BETA-42 ACCUMULATION
PRECURSOR PROTEIN
PLAQUE-FORMATION
STRESS
APOPTOSIS
PATHOLOGY
OLIGOMERS
Aβ1-42增加细胞APP水平的机制研究
学位论文
2012, 2012
王燕
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2016/02/14
Aβ
β淀粉样蛋白前体蛋白
PS1
γ-分泌酶
阿尔茨海默症
Aβ
β-amyloid precursor protein
PS1
γ-secretase
Alzheimer’s disease
原癌基因K-RAS调控APP的剪切和PS1的水平
学位论文
2012, 2012
刘杨
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2016/02/14
阿尔茨海默症
β-淀粉样蛋白前体蛋白
K-Ras
PS1
Alzheimer’s disease
β-amyloid precursor protein
K-Ras
PS1
Granulocyte colony-stimulating factor induces neurogenesis and improves cognition in amyloid precursor protein transgenic mouse model of Alzheimer\'s disease
期刊论文
China Medical Abstracts(Internal Medicine), 2012, 期号: 04, 页码: 237
作者:
Zhu ZY(朱正禹)
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
CSF
Granulocyte colony-stimulating factor induces neurogenesis and improves cognition in amyloid precursor protein transgenic mouse model of Alzheimer\'s disease
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