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上海药物研究所 [30]
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合肥物质科学研究院 [4]
大连化学物理研究所 [3]
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期刊论文 [85]
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2018 [87]
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Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4(+) T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4
期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9, 页码: 15
作者:
Hu, Qinxue
;
Gong, Sitang
;
Liu, Yalan
;
Li, Mei
;
Hu, Kai
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2019/03/05
HSV-2
CXCR3 ligands
CD4(+) T cells
recruitment
ICP4
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Wang, Anhui
;
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/06/20
beta(2)-Adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
Naunyn-schmiedebergs archives of pharmacology, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
;
Qu, Lala
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/05/08
Beta(2)-adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds
期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1902-1912
作者:
Gong, Grace Qun
;
Wang, Ke
;
Dai, Xin-Chuan
;
Zhou, Yan
;
Basnet, Rajesh
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2019/01/08
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands
期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Chen, Li-Li
;
Pan, You-Lu
;
Xie, Xiao-Yu
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2019/01/08
cannabinoids
CB1R
CB2R
heteroaryl pyrimidines
heteroaryl triazines
ligands
Positive and Negative Regulation of Glycerol Utilization by the c-di-GMP Binding Protein PIzA in Borrelia burgdorferi
期刊论文
JOURNAL OF BACTERIOLOGY, 2018, 卷号: 200, 期号: 22, 页码: 11
作者:
Yang, X. Frank
;
Gomelsky, Mark
;
Carrasco, Sebastian E.
;
He, Ming
;
Troxell, Bryan
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2018/12/29
Borrelia burgdorferi
Lyme disease
PIzA
tick-borne pathogens
Application of ITC-Based Characterization of Thermodynamic and Kinetic Association of Ligands With Proteins in Drug Design
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Su, Haixia
;
Xu, Yechun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
ITC
thermodynamics
kinetics
protein-ligand recognition
drug design
Green tea (Camellia sinensis) aqueous extract alleviates postmenopausal osteoporosis in ovariectomized rats and prevents RANKL-induced osteoclastogenesis in vitro
期刊论文
FOOD & NUTRITION RESEARCH, 2018, 卷号: 62, 页码: 11
作者:
Wu, Xin
;
Xie, Chuan-qi
;
Zhu, Qiang-qiang
;
Wang, Ming-yue
;
Sun, Bin
收藏
  |  
浏览/下载:116/0
  |  
提交时间:2018/11/12
green tea aqueous extract
osteoporosis
ovariectomy
receptor activator of the nuclear factor kappa B ligand
osteoclast
Characterization of the interaction interface and conformational dynamics of human TGIF1 homeodomain upon the binding of consensus DNA
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2018, 卷号: 1866, 期号: 10, 页码: 1021-1028
作者:
Li, Shuangli
;
Hu, Rui
;
Yao, Haijie
;
Long, Dong
;
Luo, Fan
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2018/11/05
TG interacting factor-1
DNA recognition
Interaction interface
Conformational dynamics
NMR spectroscopy
Structural insights into the recognition of phosphorylated Hop1 by Mek1
期刊论文
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2018, 卷号: 74, 页码: 1027-1038
作者:
Xie, Changlin
;
He, Chao
;
Jiang, Yiyang
;
Yu, Hailong
;
Cheng, Lin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/25
meiotic recombination
Mek1
Hop1
FHA domain
phosphointeraction
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