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复旦大学上海医学院 [11]
中国医学科学院 北京... [6]
山东大学 [4]
西安交通大学 [3]
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期刊论文 [32]
会议论文 [3]
发表日期
2017 [35]
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Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:
Chen, Lingfeng
;
Fu, Weitao
;
Feng, Chen
;
Qu, Rong
;
Tong, Linjiang
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Epidermal growth factor receptor
Tyrosine kinase inhibitors
Non-small cell lung cancer
T790M
Mutant-selective
Facile Synthesis of Novel Perfluorocarbon-Modulated 4-Anilinoquinazoline Analogues
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2017, 卷号: 35, 期号: 11, 页码: 1693-1700
作者:
Shi, Huiping
;
Lai, Bonan
;
Chen, Shizhen
;
Zhou, Xin
;
Nie, Jing
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2018/11/05
4-anilinoquinazolines
Perfluorocarbon (Pfc)
Nucleophilic Substitution Reaction
Synthesis
Epidermal Growth Factor Receptor (Egfr)
Structure-Guided Design of C4-alkyl-1,4-dihydro-2H-pyrimido[4,5-d][1,3]oxazin-2-ones as Potent and Mutant-Selective Epidermal Growth Factor Receptor (EGFR) L858R/T790M Inhibitors
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Hao, Yongjia
;
Lyu, Jiankun
;
Qu, Rong
;
Sun, Deheng
;
Zhao, Zhenjiang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Prognostic and predictive value of serum carcinoembryonic antigen levels in advanced non-small cell lung cancer patients with epidermal growth factor receptor sensitive mutations and receiving tyrosine kinase inhibitors
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 41
作者:
Zhao, Xin Min
;
Zhao, Jing
;
Xing, Kai Lin
;
Sun, Si
;
Luo, Zhi Guo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
non-small cell lung cancer
chemotherapy
epidermal growth factor receptor
tyrosine kinase inhibitors
carcinoembryonic antigen
[Advances in the Transformation to Small Cell Lung Cancer from Non-small Cell Lung Cancer Following Acquired Drug-resistance to EGFR Tyrosine Kinase Inhibitors].
期刊论文
Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2017, 卷号: 20, 期号: 10
作者:
Zhang Wenqiu
;
Li Yongqi
;
Wu Di
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Drug resistance
Epidermal growth factor receptor tyrosine kinase inhibitor
Lung neoplasms
Mechanism
Transformation
Genome-Wide Screen of DNA Methylation Changes Reveals GABBR2 as a Novel Potential Target for EGFR 19 Deletion Adenocarcinoma with Erlotinib
会议论文
作者:
Liu, Fatao
;
Zhou, Yi
;
Zhou, Zhen
;
Liu, Yun
;
Chen, Zhiwei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)
lung adenocarcinoma
methyl-sensitive cut counting sequencing (MSCC)
methylation
Mimicking the BIM BH3 domain overcomes resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 65
作者:
Xia, Jinjing
;
Bai, Hao
;
Yan, Bo
;
Li, Rong
;
Shao, Minhua
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
epidermal growth factor receptor (EGFR)
tyrosine kinase inhibitors (TKIs)
BIM deletion polymorphism
erlotinib
ABT-737
A multicenter survey of first-line treatment patterns and gene aberration test status of patients with unresectable Stage IIIB/IV nonsquamous non-small cell lung cancer in China (CTONG 1506)
期刊论文
BMC CANCER, 2017, 卷号: 17
作者:
Zhou, Qing
;
Song, Yong
;
Zhang, Xin
;
Chen, Gong-Yan
;
Zhong, Dian-Sheng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Chemotherapy
China
Epidermal growth factor receptor
First-line anticancer treatment
Non-small cell lung cancer
Tyrosine kinase inhibitor
High probability and frequency of EGFR mutations in non-small cell lung cancer with brain metastases
期刊论文
JOURNAL OF NEURO-ONCOLOGY, 2017, 卷号: 135, 期号: 2
作者:
Ge, Mengxi
;
Zhuang, Yingjie
;
Zhou, Xinli
;
Huang, Ruofan
;
Liang, Xiaohua
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Brain metastases
Non-small cell lung cancer
Epidermal growth factor receptor
Tyrosine kinase inhibitor
Disease-free survival improved by use of adjuvant EGFR tyrosine kinase inhibitors in resectable non-small cell lung cancer: an updated meta-analysis
期刊论文
JOURNAL OF THORACIC DISEASE, 2017, 卷号: 9, 期号: 12
作者:
Yuan, Yonggang
;
Huang, Qingyuan
;
Gu, Chang
;
Chen, Haiquan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Epidermal growth factor receptor (EGFR)
tyrosine kinase inhibitor (TKI)
lung cancer
adjuvant
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