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科研机构
上海药物研究所 [12]
内容类型
期刊论文 [12]
发表日期
2013 [12]
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共12条,第1-10条
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发表日期:2013
专题:上海药物研究所
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Reversal of multidrug resistance by stimuli-responsive drug delivery systems for therapy of tumor
期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2013, 卷号: 65, 期号: 13-14, 页码: 1699-1715
作者:
Yin, Qi
;
Shen, Jianan
;
Zhang, Zhiwen
;
Yu, Haijun
;
Li, Yaping
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Stimuli
Responsive
Drug delivery
Multidrug resistance
Tumor
Chemotherapy
Berberine combined with 2-deoxy-D-glucose synergistically enhances cancer cell proliferation inhibition via energy depletion and unfolded protein response disruption
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 卷号: 1830, 期号: 11, 页码: 5175-5183
作者:
Fan, Li-xia
;
Liu, Chang-mei
;
Gao, An-hui
;
Zhou, Yu-bo
;
Li, Jia
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Berberine
2-Dem-D-glucose
UPR
GRP78
Cancer metabolism
A computational analysis of binding modes and conformation changes of MDM2 induced by p53 and inhibitor bindings
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2013, 卷号: 27, 期号: 11, 页码: 965-974
作者:
Chen, Jianzhong
;
Wang, Jinan
;
Zhu, Weiliang
;
Li, Guohui
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
p53-MDM2 interaction
Molecular dynamics simulation
PCA
MM-GBSA
Design, Synthesis, and Biological Evaluation of Novel Conformationally Constrained Inhibitors Targeting EGFR
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 4, 期号: 10, 页码: 974-978
作者:
Wu, Jianwei
;
Chen, Wenteng
;
Xia, Guangxin
;
Zhang, Jing
;
Shao, Jiaan
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
Anticancer
kinase inhibitor
EGFR
conformationally constrained
Magnetic Nanoparticles for Tumor Imaging and Therapy: A So-Called Theranostic System
期刊论文
PHARMACEUTICAL RESEARCH, 2013, 卷号: 30, 期号: 10, 页码: 2445-2458
作者:
He, Huining
;
David, Allan
;
Chertok, Beata
;
Cole, Adam
;
Lee, Kyuri
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
brain tumor/cancer
cell-penetrating peptide
magnetic nanoparticles
theranostic system
tumor imaging and therapy
Ac-cel, a Novel Antioxidant, Protects Against Hydrogen Peroxide-induced Injury in PC12 Cells via Attenuation of Mitochondrial Dysfunction
期刊论文
JOURNAL OF MOLECULAR NEUROSCIENCE, 2013, 卷号: 50, 期号: 3, 页码: 453-461
作者:
Guo, Xianjun
;
Chen, Yuting
;
Liu, Qunfang
;
Wu, Jian
;
Wang, Luoyi
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Apoptosis
Antioxidant
Hydrogen peroxide
Mitochondria
Neuroprotection
Reactive oxygen species
Multifunctional Nanoparticles Improve Therapeutic Effect for Breast Cancer by Simultaneously Antagonizing Multiple Mechanisms of Multidrug Resistance
期刊论文
BIOMACROMOLECULES, 2013, 卷号: 14, 期号: 7, 页码: 2242-2252
作者:
Yin, Qi
;
Shen, Jianan
;
Zhang, Zhiwen
;
Yu, Haijun
;
Chen, Lingli
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Identifying Chemicals with Potential Therapy of HIV Based on Protein-Protein and Protein-Chemical Interaction Network
期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 6
作者:
Li, Bi-Qing
;
Niu, Bing
;
Chen, Lei
;
Wei, Ze-Jun
;
Huang, Tao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Anthraquinone Derivatives as Potent Inhibitors of c-Met Kinase and the Extracellular Signaling Pathway
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 4, 期号: 4, 页码: 408-413
作者:
Liang, Zhongjie
;
Ai, Jing
;
Ding, Xiao
;
Peng, Xia
;
Zhang, Dengyou
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Anthraquinone derivatives
c-Met kinase inhibitors
binding affinity with HGF
Induction of apoptosis in non-small cell lung cancer by downregulation of MDM2 using pH-responsive PMPC-b-PDPA/siRNA complex nanoparticles
期刊论文
BIOMATERIALS, 2013, 卷号: 34, 期号: 11, 页码: 2738-2747
作者:
Yu, Haijun
;
Zou, Yonglong
;
Jiang, Lei
;
Yin, Qi
;
He, Xinyu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Non-small cell lung cancer
MDM2
pH-responsive
Nanoparticles
siRNA
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