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Mechanistic Studies of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis Using a Tyrosine Analogue, 2-Amino-3-(4-hydroxy-3-(methoxyl) phenyl) Propanoic Acid (MeOTyr)
期刊论文
ACS CATALYSIS, 2019, 卷号: 9, 期号: 1
作者:
Chen, Li
;
Naowarojna, Nathchar
;
Chen, Bin
;
Xu, Meiling
;
Quill, Melissa
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
ovothiol
sulfur-containing natural products
kinetic isotope effect
unnatural amino acid
biosynthesis
A novel recombinant RANKL vaccine prepared by incorporation of an unnatural amino acid into RANKL and its preventive effect in a murine model of collagen-induced arthritis.
期刊论文
International immunopharmacology, 2018, 卷号: 64, 页码: 326-332
作者:
Wu Tailin
;
Li Feng
;
Sha Xin
;
Li Fuyang
;
Zhang Bobo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
Rheumatoid arthritis
Immunization
Unnatural amino acid
Vaccine
RANKL
A new vaccine targeting RANKL, prepared by incorporation of an unnatural Amino acid into RANKL, prevents OVX-induced bone loss in mice
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 页码: 648-654
作者:
Li, Feng
;
Li, Huan
;
Zhai, Qian
;
Li, Fuyang
;
Wu, Tailin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/11/26
Osteoclast
RANKL
Unnatural amino acid
Vaccine
Osteoporosis
Improved chemical synthesis of o-nirtrobenzyl-tyrosine for concise site-specific N-15-tyrosine NMR analysis demonstrated by plant ABA receptor PYL10
期刊论文
TETRAHEDRON LETTERS, 2017, 卷号: 58, 期号: 39, 页码: 3764-3767
作者:
Guo, Xiaoqi
;
Zhang, Bo
;
He, Yao
;
Liu, Yangzhong
;
Tian, Changlin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2018/08/17
Unnatural Amino Acid
Tyrosine
Protein Nmr Analysis
Abscisic Acid Receptor
Pyl-10
Lanthanoid tagging via an unnatural amino acid for protein structure characterization
期刊论文
JOURNAL OF BIOMOLECULAR NMR, 2017, 卷号: 67, 期号: 4, 页码: 273-282
作者:
Gu, Xin-Hua
;
Tang, Chun
;
Dong, Xu
;
Jiang, Wen-Xue
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2017/11/24
Unnatural Amino Acid
Azide-alkyne Cycloaddition
Pseudo-contact Shift
Protein Structure
Transient Protein Complex
Rational design of metalloenzymes: From single to multiple active sites
期刊论文
Coordination Chemistry Reviews, 2017, 卷号: 336, 期号: Volume 336, 页码: 1-27
作者:
Lin, Ying-Wu*
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  |  
浏览/下载:22/0
  |  
提交时间:2019/12/27
UAAs
unnatural amino acids
Rd
rubredoxin
EPR
electron paramagnetic resonance
Az
azurin
SOR
superoxide reductase
PDB
protein data bank
6-PGLac
6-phosphogluconolactonase
H-bond
hydrogen-bond
NIR
nitrite reductase
ET
electron transfer
3SCC
three stranded coiled coil
Bpy-Ala
(2,2′-bipyridinine-5-yl)alanine
CcO
cytochrome c oxidase
N2OR
nitrous oxidase reductase
XANES
X-ray absorption near-edge structure
DF
Due Ferri
4-AP
4-amino-phenol
POP
prolyl oligopeptidase
ee
enantiomeric excess
HCO
heme-copper oxidase
NOR
nitric oxide reductase
MnP
manganese peroxidase
Mb
myoglobin
RFQ-rR
freeze-quench resonance Raman
CcP
Cyt c peroxidase
BMC
microcompartment
CYP
cytochrome P450
TON
turnover number
TDHC
tetradehydrocorrin
NB
nitrobindin
RCM
ring-closing metathesis
ROMP
ring-opening metathesis polymerization
SAV
steptavidin
NCS
neocarzinostatin
BLG
-Lactoglobulin
HSA
human serum albumin
BSA
bovine serum albumin
ITC
isothermal titration calorimetry
AldO
alditol oxidase
FAD
flavin adenine dinucleotide
MP
microperoxidase
HB
heme-binding
GTL
Geobacillus thermocatenulatus lipase
4NPA
4-nitrophenyl acetate
LmrR
Lactococcal multidrug resistance Regulator
ABTS
2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt
mCPBA
meta-chloroperbenzoic acid
Fd
ferredoxin
Fld
flavodoxin
HTHP
hexameric Tyr-coordinated heme protein
AFM
atomic force microscopy
TEM
transmission electron microscopy
MRI
magnetic resonance imaging
Metalloproteins
Metalloenzymes
Protein design
Multiple active sites
Biocatalysts
Design and Synthesis of a Novel Series of Opioid Dipeptides and Evaluation of Their Analgesic Effect in Vivo
期刊论文
ACTA CHIMICA SINICA, 2016, 卷号: 74, 期号: 1, 页码: 44-48
作者:
Liu, X
;
Zhao, L
;
Wang, Y
;
Mou, LY
;
Zhang, YX
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2017/01/10
opioid peptide
antinociception
structure-activity relationship
blood-brain barrier
unnatural amino acid
Design, synthesis, and evaluation of new endomorphin analogs with enhanced central antinociception after peripheral administration
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 22, 页码: 5393-5397
作者:
Liu, X
;
Zhao, L
;
Wang, Y
;
Mou, LY
;
Yang, JX
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/01/13
Endomorphin
Analgesia
Blood-brain barrier
Unnatural amino acid
Characterization of (R)-selective amine transaminases identified by in silico motif sequence blast
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2015, 卷号: 99, 期号: 6, 页码: 2613-2621
作者:
Jiang, Jinju
;
Chen, Xi
;
Zhang, Dalong
;
Wu, Qiaqing
;
Zhu, Dunming
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2016/06/23
omega-Transaminase
Chiralamine
Unnatural amino acid
Biocatalysis
A highly efficient approach to unnatural amino-acids containing 3-hydroxyoxindole skeleton via a one-pot, three-component procedure
期刊论文
TETRAHEDRON LETTERS, 2015, 卷号: 56, 期号: 4, 页码: 586-589
作者:
Huang, Huang
;
Xu, Yong
;
Mao, Fei
;
Zhu, Jin
;
Jiang, Hualiang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Unnatural amino-acid
3-Hydroxyoxindole
Multicomponent reaction
Isatin
Benzophenone imine
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