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科研机构
西安交通大学 [3]
上海药物研究所 [2]
上海大学 [2]
湖南大学 [2]
北京大学 [1]
山东大学 [1]
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期刊论文 [14]
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2019 [3]
2018 [1]
2017 [2]
2016 [2]
2015 [3]
2012 [1]
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Mutant p53 in cancer therapy-the barrier or the path
期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2019, 卷号: 11, 期号: 4
作者:
Zhou, Xiang
;
Hao, Qian
;
Lu, Hua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
mutant p53
gain-of-function
cancer therapy
chemoresistance
synthetic lethality
Identification of synthetic lethality based on a functional network by using machine learning algorithms
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 页码: 405-416
作者:
Li, JiaRui[1]
;
Lu, Lin[2]
;
Zhang, Yu-Hang[3]
;
Liu, Min[4]
;
Chen, Lei[5]
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/04/22
maximum relevance and minimum redundancy (mRMR)
random forest (RF)
synthetic lethality
Identification of synthetic lethality based on a functional network by using machine learning algorithms
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: Vol.120 No.1, 页码: 405-416
作者:
Li, JiaRui
;
Lu, Lin
;
Zhang, Yu-Hang
;
Liu, Min
;
Chen, Lei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/17
maximum relevance and minimum redundancy (mRMR)
random forest (RF)
synthetic lethality
Lipid-Based Liquid Crystalline Nanoparticles Facilitate Cytosolic Delivery of siRNA via Structural Transformation
期刊论文
NANO LETTERS, 2018, 卷号: 18, 期号: 4, 页码: 2411-2419
作者:
He, Shufang
;
Fan, Weiwei
;
Wu, Na
;
Zhu, Jingjing
;
Miao, Yunqiu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Lipids
liquid crystalline nanoparticles
siRNA delivery
endosomal escape
synthetic lethality
Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 4156-4168
作者:
He, Jin-Xue
;
Wang, Meng
;
Huan, Xia-Juan
;
Chen, Chuan-Huizi
;
Song, Shan-Shan
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
MPH
PARP inhibitor
homologous recombination
antitumor activity
synthetic lethality
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair
期刊论文
ANNALS OF ONCOLOGY, 2017
Shenoy, T. R.
;
Boysen, G.
;
Wang, M. Y.
;
Xu, Q. Z.
;
Guo, W.
;
Koh, F. M.
;
Wang, C.
;
Zhang, L. Z.
;
Wang, Y.
;
Gil, V.
;
Aziz, S.
;
Christova, R.
;
Rodrigues, D. N.
;
Crespo, M.
;
Rescigno, P.
;
Tunariu, N.
;
Riisnaes, R.
;
Zafeiriou, Z.
;
Flohr, P.
;
Yuan, W.
;
Knight, E.
;
Swain, A.
;
Ramalho-Santos, M.
;
Xu, D. Y.
;
de Bono, J.
;
Wu, H.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
chromatin remodeler CHD1
PCa
DDR
homologous recombination
non-homologous end joining
synthetic lethality
REGULATES 53BP1 STABILITY
MAMMALIAN-CELLS
PATHWAY CHOICE
MOUSE MODEL
CHROMATIN
TRANSCRIPTION
CASTRATION
PROTEIN
PTEN
RECRUITMENT
Low-fidelity alternative DNA repair carcinogenesis theory may interpret many cancer features and anticancer strategies
期刊论文
FUTURE ONCOLOGY, 2016, 卷号: 12, 页码: 1897-1910
作者:
Jiang, Chuo[1]
;
Starr, Shane[2]
;
Chen, Fuxue[3]
;
Wu, Jiaxi[4]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/26
alternative DNA repair
carcinogenesis
synthetic lethality
The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancer.
期刊论文
Oncotarget, 2016, 卷号: Vol.7 No.24, 页码: 37331-37346
作者:
Gao D
;
Herman JG
;
Guo M.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/02/27
DNA damage repair
DNA methylation
MGMT
PARP inhibitor
synthetic lethality
Autoimmune response to PARP and BRCA1/BRCA2 in cancer.
期刊论文
Oncotarget, 2015, 卷号: 6, 期号: [db:dc_citation_issue], 页码: 11575-84
作者:
Zhu Qing
;
Han Su-Xia
;
Zhou Cong-Ya
;
Cai Meng-Jiao
;
Dai Li-Ping
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/02
synthetic lethality
tumor-associated antigen (TAA)
autoimmune
autoantibody
DNA repair enzyme poly (ADP-Ribose) polymerase 1 (PARP1)/BRCA1/BRCA2
Autoimmune response to PARP and BRCA1/BRCA2 in cancer
期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: [db:dc_citation_issue], 页码: 11575-11584
作者:
Zhu, Qing
;
Han, Su-Xia
;
Zhou, Cong-Ya
;
Cai, Meng-Jiao
;
Dai, Li-Ping
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
synthetic lethality
tumor-associated antigen (TAA)
autoimmune
autoantibody
DNA repair enzyme poly (ADP-Ribose) polymerase 1 (PARP1)/BRCA1/BRCA2
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