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科研机构
四川大学 [1]
天津大学 [1]
中南林业科技大学 [1]
生态环境研究中心 [1]
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期刊论文 [3]
学位论文 [1]
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2014 [1]
2011 [1]
2010 [1]
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环境科学::环境化学 [1]
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Identification of Potential MEK1 Inhibitors by Pharmacophore-based Virtual Screening and MD Simulations
期刊论文
Letters in Drug Design & Discovery, 2014, 卷号: Vol.11 No.7, 页码: 894-907
作者:
Huanhuan Shi
;
Lu Zhou
;
Guangkai Bao
;
Qianying Yi
;
Suwen Zhou
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  |  
浏览/下载:3/0
  |  
提交时间:2019/03/01
3D-QSAR
Allosteric
binding
cavity
MD
simulations
MEK1
Molecular
docking
Virtual
screening.
饮料及红酒中未知添加剂(物)色谱-质谱筛查确证方法研究
学位论文
博士后, 北京: 中国科学院研究生院, 2011
冯峰
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  |  
浏览/下载:87/0
  |  
提交时间:2011/09/13
食品添加剂
甜味剂
着色剂
串联质谱
飞行时间质谱
筛查
food additives
sweetener
colorants
tandem mass spectrometry
time of flight mass spectrometry
screening.
Identification of a chitin deacetylase producing bacteria isolated from soil and its fermentation optimization
期刊论文
AFRICAN JOURNAL OF MICROBIOLOGY RESEARCH, 2010, 卷号: 4, 期号: 23, 页码: 2597-2603
作者:
Zhou, Guoying*
;
Zhang, Huaiyun
;
He, Yuanhao
;
He, Li
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/28
Chitin deacetylase (CDA) catalyzes the conversion of chitin to chitosan by the deacetylation of N-acetyl-D-glucosamine residues. In this study
9 strains of bacteria with chitin deacetylase activity were isolated from canal mud samples from theXiangjiang River in Changsha
Hunan Province. Of these 9 strains
the Z7 strain had the highest chitin deacetylase activity
as determined by enzyme assay screening. Based on its culture
morphological
physiological characteristics and molecular identification
strain Z7 was identified as Bacillus amyloliquefaciens. Yeast extract at a concentration of 1.0% was an ideal nitrogen source for production of CDA (16.78 Eu/ml). Starch at 2% functioned best as the major carbon source for optimum production of CDA (17.84 Eu/ml). Magnesium sulfate at a concentration of 0.04% was an ideal inorganic salt for CDA production (17.45 Eu/ml). Ideal pH and temperature for optimum production of CDA by this strain were pH 6 and 37˚C.
Recent Developments on Coronavirus Main Protease/3C Like Protease Inhibitors
期刊论文
Recent Patents on Anti-Infective Drug Discovery, 卷号: Vol.8 No.2, 页码: 150-156
作者:
Zhao, Q.a
;
Weber, E.a
;
Yang, H.b
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浏览/下载:2/0
  |  
提交时间:2019/11/21
Antiviral
3C like proteases
coronavirus
inhibitor
main protease
natural product
rational drug design
virtual screening.
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