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Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan. 期刊论文
Acta pharmaceutica Sinica. B, 2019, 卷号: No.1, 页码: 157-166
作者:  Yiqiao Gao;  Wei Li;  Jiaqing Chen;  Xu Wang;  Yingtong Lv
收藏  |  浏览/下载:55/0  |  提交时间:2019/12/17
AUC-ROC,  area  under  receiver  operating  characteristic  BHB,  β-hydroxybutyric  acid  Biomarkers  C,  control  group  CA,  cholic  acid  CPT-11,  irinotecan  Complicating  toxicity  DBIL,  direct  bilirubin  DCA,  deoxycholic  acid  Diarrhea  FDR,  false  discovery  rate  GCA,  glycocholic  acid  Gastrointestinal  toxicity  IBIL,  indirect  bilirubin  IT-TOF/MS,  ion  trap/time-offlight  hybrid  mass  spectrometry  Individual  differences  Irinotecan  Lys,  lysine  MSTFA,  N-methyl-N-trifluoroacetamide  Metabolomics  NS,  non-sensitive  group  NSgt,  non-sensitive  for  gastrointestinal  toxicity  NSmt,  non-sensitive  for  myelosuppression  toxicity  OPLS-DA,  orthogonal  partial  least-squares-discriminant  analysis  PCA,  principal  component  analysis  PLS-DA,  partial  least-squares-discriminant  analysis  Phe,  phenylalanine  Prediction  QC,  quality  control  RSD,  relative  standard  deviation  S,  sensitive  group  Sgt,  sensitive  for  gastrointestinal  toxicity  Smt,  sensitive  for  myelosuppression  toxicity  T,  CPT-11  treated  group  Trp,  tryptophan  UFLC,  ultrafast  liquid  chromatography  VIP,  variable  importance  in  the  projection  pFDR,  false-discovery-rate-adjusted  P  value  
Density Characteristics of the CO2-CH4 Binary System: Experimental Data at 313-353 K and 3-18 MPa and Modeling from the PC-SAFT EoS 期刊论文
JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2018, 卷号: 63, 页码: 4368-4380
作者:  Liu, Shuyang;  Zhao, Changzhong;  Lv, Junchen;  Lv, Pengfei;  Zhang, Yi
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/02
Density Measurements of Propellant EHF-TU at (3 to 7) MPa Supercritical Pressures 期刊论文
JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2018, 卷号: 63, 页码: 1961-1968
作者:  Wen, Jie;  Zhang, Nan;  Fu, Yanchen;  Xu, Guoqiang;  Huang, Haoran
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/30
Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS 期刊论文
Journal of Pharmaceutical and Biomedical Analysis, 2018, 卷号: 150, 页码: 199-207
作者:  Chen, Man-Yun;  Shao, Li;  Zhang, Wei;  Wang, Chong-Zhi;  Zhou, Hong-Hao
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/27
ACN  acetonitrile  DAD  diode array-detector  DMSO  dimethyl sulphoxide  ESI  electrospray ionization  GAM  general anaerobic medium  GF1  ginsenoside F1  GC-K  ginsenoside compound K  GRh2  ginsenoside Rh2  HF-HP  high-fat and high-protein  HPLC-DAD-Q-TOF-MS/MS  high-performance liquid chromatography coupled with diode array detection/quadrupole tandem time-of-flight mass spectrometry  LF-PF  low-fat and plant fiber-rich  LLE  liquid-liquid extraction  PPD  protopanaxadiol  PPT  protopanaxatriol  PNS  Panax notoginseng saponins  RSDs  relative standard deviations  SEM  standard deviation of mean  TICs  total ion chromatograms  Panax notoginseng  Ginsenosides  Gut microbiota  Biotransformation  Metabolic profile  HPLCDAD-Q-TOF-MS/MS  
Occurrence of and human exposure to parabens, benzophenones, benzotriazoles, triclosan and triclocarban in outdoor swimming pool water in Changsha, China 期刊论文
Science of the Total Environment, 2017, 卷号: 605-606, 页码: 1064-1069
作者:  Lu, Jing;  Mao, Huiyue;  Li, Haipu*
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/03
Influence Analysis of Satellite Drift Angle on Spectrum Recovery Precision of Large Aperture Static Interferometer Spectrometer 会议论文
作者:  Li, Siyuan;  Liu, Huan;  Zhang, Geng;  Zhang, Zhoufeng;  Zhao, Qiang
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/26
Wafer-level fabrication of nanocone forests by plasma repolymerization technique for surface-enhanced Raman scattering devices 期刊论文
APPLIED SURFACE SCIENCE, 2017
Mao, Haiyang; Huang, Chengjun; Wu, Wengang; Xue, Mei; Yang, Yudong; Xiong, Jijun; Ming, Anjie; Wang, Weibing
收藏  |  浏览/下载:6/0  |  提交时间:2017/12/03
Estimating freshness of carp based on EIS morphological characteristic 期刊论文
JOURNAL OF FOOD ENGINEERING, 2017, 卷号: 193, 页码: 58-67
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收藏  |  浏览/下载:2/0  |  提交时间:2019/12/24
A new model for the accurate calculation of natural gas viscosity 期刊论文
Natural Gas Industry B, 2017, 卷号: 4, 期号: 2, 页码: 100-105
作者:  XiaohongYang;  ShunxiZhang;  WeilingZhu
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/27
A consensus accuracy model for group decision making with [0,1] reciprocal preference relations 期刊论文
IEEE International Fuzzy Systems Conference Proceedings, 2016, 页码: 1709-1716
作者:  Chen, Huayou;  Wang, Feng;  Wu, Peng;  Zhou, Ligang
收藏  |  浏览/下载:1/0  |  提交时间:2019/04/24


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