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Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12
作者:
Lin, Tingting
;
Li, Jiacheng
;
Liu, Liping
;
Li, Yuanqing
;
Jiang, Hualiang
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/05/24
CDK2 inhibitor
Selectivity
Anti-proliferative potency
Rational Design, synthesis and biological evaluation of novel triazole derivatives as potent and selective PRMT5 inhibitors with antitumor activity
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 8, 页码: 775-785
作者:
Zhu, Kongkai
;
Shao, Jingwei
;
Tao, Hongrui
;
Yan, Xue
;
Luo, Cheng
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
PRMT5 inhibitor
Anti-proliferative
Cellular target validation
Design and synthesis
Pirfenidone suppresses the abnormal activation of human Müller cells after platelet-derived growth factor-BB stimulation.
期刊论文
International journal of ophthalmology, 2019, 卷号: 12, 期号: 7
作者:
Yang Wen-Yan
;
Tao Yi-Jin
;
Chen Qin
;
Wang Li
;
Yang Xiao
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/04
Müller cells
pirfenidone
platelet-derived growth factor-BB
proliferative vitreoretinopathy
transforming growth factor-β
Novel Resveratrol-chalcone Derivatives: Synthesis and Biological Evaluation
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 5
作者:
Liu, Bei
;
Zhu, Ping
;
Zheng, Xi
;
Ma, Yulu
;
Wan, Chunping
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/04
Resveratrol
chalcon
anti-inflammatory activity
anti-proliferative activity
FACs analysis
inflammation
Predictive risk factors for exudative retinal detachment after vitrectomy for proliferative diabetic retinopathy
期刊论文
MEDICINE, 2019, 卷号: 98, 期号: 8
作者:
Li, Jia
;
Sun, Di-Fang
;
Wang, Yan-Li
;
Wang, Bin
;
Xu, Chun-Ling
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
exudative retinal detachment
proliferative diabetic retinopathy
vitrectomy
Single-Dose Intravitreal Conbercept before Panretinal Photocoagulation as an Effective Adjunctive Treatment in Chinese Proliferative Diabetic Retinopathy
期刊论文
OPHTHALMOLOGICA, 2019, 卷号: 242, 期号: 2
作者:
Zhang, Quan
;
Zhang, Ting
;
Zhuang, Hong
;
Sun, Zhongcui
;
Qin, Yaowu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Single-dose intravitreal conbercept
Panretinal photocoagulation
Chinese proliferative diabetic retinopathy
Comprehensive circular RNA profiling of proliferative vitreoretinopathy and its clinical significance
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 111
作者:
Yao, Jin
;
Hu, Li-Li
;
Li, Xiu-Miao
;
Shan, Kun
;
Zhou, Rong-Mei
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  |  
浏览/下载:37/0
  |  
提交时间:2019/12/05
Proliferative vitreoretinopathy
Circular RNA
Epiretinal membrane
Anti-proliferative activity and structure-activity relationship of honokiol derivatives
期刊论文
Bioorganic & Medicinal Chemistry, 2019
作者:
Ding Lin
;
Zhongzhong Yan
;
Aiyu Chen
;
Jiao Ye
;
Aixi Hu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/13
Honokiol
Anti-proliferative
Structure-activity relationship
3D-QASR
Theoretical calculations
Anti-proliferative activity and structure-activity relationship of honokiol derivatives.
期刊论文
Bioorganic & medicinal chemistry, 2019
作者:
Lin, D
;
Yan, ZZ
;
Chen, AY
;
Ye, J
;
Hu, AX
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/12/13
3D-QASR
Anti-proliferative
Honokiol
Structure-activity relationship
Theoretical calculations
Supercritical CO fluid extraction of Croton crassifolius Geisel root: chemical composition and anti-proliferative, autophagic, apoptosis-inducing, and related molecular effects on A549 tumour cells
期刊论文
Phytomedicine, 2019, 页码: 152846
作者:
Chao Liu
;
Rui-rui Zhang
;
Yue-ming Wang
;
Jing Zhang
;
Qing Wang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/17
Croton
crassifolius
essential
oil
Anti-proliferative
Apoptosis-inducing
Molecular
mechanism
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