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厦门大学 [3]
复旦大学上海医学院 [3]
上海中医药大学 [3]
福州大学 [3]
西安交通大学 [2]
湖南农业大学 [2]
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期刊论文 [24]
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2019 [3]
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2017 [3]
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Xenobiotic pregnane X receptor promotes neointimal formation in balloon-injured rat carotid arteries.
期刊论文
Journal of cellular physiology, 2019, 卷号: 234, 页码: 4342-4351
作者:
Zhang Meiqian
;
Zhang Zihui
;
Xie Xinya
;
Yao Qinyu
;
Liu Jia
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  |  
浏览/下载:24/0
  |  
提交时间:2019/11/19
pregnane X receptor (PXR)
neointimal formation
proliferation
migration
smooth muscle cell (SMC)
Patchouli alcohol activates PXR and suppresses the NF-κB-mediated intestinal inflammatory
期刊论文
Journal of ethnopharmacology, 2019, 卷号: 248, 页码: 112302
作者:
Zhang Guohui
;
Liu Meijing
;
Song Meng
;
Wang Jueyu
;
Cai Jiazhong
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  |  
浏览/下载:26/0
  |  
提交时间:2019/12/30
Intestinal inflammation
Nuclear factor-kappa B (NF-κB)
Patchouli alcohol (PA)
Pregnane X receptor (PXR)
currenttrendsindrugmetabolismandpharmacokinetics
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1113
作者:
Liu Dongyang
;
Hou Xiangyu
;
Tang Lan
;
Wang Xin
;
Lyu Yuanfeng
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  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
ARYL-HYDROCARBON RECEPTOR
BLOOD-BRAIN-BARRIER
ORGANIC ANION TRANSPORTERS
CHRONIC KIDNEY-DISEASE
PREGNANE-X-RECEPTOR
P-GLYCOPROTEIN
QUANTITATIVE PREDICTION
CYTOCHROME-P450 ENZYMES
DOWN-REGULATION
IN-VIVO
Pharmacokinetics
Drug metabolism
Drug-drug interactions
Modeling
Metabolizing enzymes
Transporters
Nuclear receptors
Noncoding RNAs
Activation of PXR inhibits LPS-induced NF-kappa B activation by increasing I kappa B alpha expression in HepG2 cells
期刊论文
MOLECULAR & CELLULAR TOXICOLOGY, 2018, 卷号: 14, 页码: 93-104
作者:
Ye, Nanhui
;
Wang, Hang
;
Li, Qiaoling
;
Lin, Chaotong
;
Feng, Huahua
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  |  
浏览/下载:14/0
  |  
提交时间:2019/11/21
Inhibitor of kappa B alpha
Cancer prevention
Pregnane X receptor
Anti-inflammation
Pregnane X Receptor Polymorphisms and Risk of Inflammatory Bowel Disease: A Meta-Analysis
期刊论文
IMMUNOLOGICAL INVESTIGATIONS, 2017, 卷号: 46, 期号: 6, 页码: 566-576
作者:
Guo, Xiaolan
;
Yan, Ming
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Inflammatory bowel disease
meta-analysis
polymorphism
pregnane X
receptor gene
Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage
期刊论文
Toxicology Letters, 2017, 卷号: 275, 页码: 67-76
作者:
Cui, Hongmei
;
Gu, Xinsheng
;
Chen, Jingshu
;
Xie, Ying
;
Ke, Sui
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
PXR
pregnane X receptor
AhR
aryl hydrocarbon receptor
DRE
dioxin response element
BaP
benzo[a]pyrene
RIF
rifampicin
H2Ax
histone 2Ax
CAR
constitutive androstane receptor
FXR
farnesoid X receptor
CYP450
cytochrome P450
EROD
7-ethoxyresorufin-O-deethylase
PAH
polycyclic aromatic hydrocarbon
ER
estrogen receptor
PXR
AhR
BaP
cyp1a1
DNA damages
Alpha-ketoglutarate suppresses the NF-kappaB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway.
期刊论文
Oncotarget, 2017, 卷号: 8, 期号: 61, 页码: 102974-102988
作者:
He, Liuqin
;
Li, Huan
;
Huang, Niu
;
Zhou, Xihong
;
Tian, Junquan
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
AKG
CYP450
NF-kappaB
intestinal inflammation
pregnane X receptor
SMS regulates the expression and function of P-gp and MRP2 in Caco-2 cells
期刊论文
CELL BIOLOGY AND TOXICOLOGY, 2016, 卷号: 32, 期号: 6
作者:
Jin, Guiying
;
Li, Yang
;
Zhu, Yuwen
;
Du, Lisha
;
Yan, Junkai
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/05
Sphingomyelin synthase
P-glycoprotein
Multidrug resistance protein 2
Pregnane X receptor
Phosphorylated signal pathways
PXR Mediated Protection against Liver Inflammation by Ginkgolide A in Tetrachloromethane Treated Mice
期刊论文
BIOMOLECULES & THERAPEUTICS, 2016, 卷号: 24, 页码: 40-48
作者:
Ye, Nanhui
;
Wang, Hang
;
Hong, Jing
;
Zhang, Tao
;
Lin, Chaotong
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/11/21
I kappa B alpha expression
Liver inflammation
Pregnane X receptor
Ginkgolide A
PXR knock-down
Protein arginine methyltransferase 1 may be involved in pregnane x receptor-activated overexpression of multidrug resistance 1 gene during acquired multidrug resistant
期刊论文
Oncotarget, 2016, 卷号: Vol.7 No.15, 页码: 20236-20248
作者:
Li, T.
;
Kong, A.-N.T.
;
Ma, Z.
;
Liu, H.
;
Liu, P.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/02/25
Multidrug
resistance
P-glycoprotein
Pregnane
X
receptor
Protein
arginine
methyl
transferase
1
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