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复旦大学上海医学院 [4]
上海药物研究所 [1]
武汉大学 [1]
中国医学科学院 北京... [1]
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期刊论文 [7]
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Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 beta (GSK-3 beta)
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20
作者:
Gao, Yang
;
Zhang, Peng
;
Cui, Anfeng
;
Ye, De-Yong
;
Xiang, Meng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Glycogen synthase kinase 3 beta
Sirtuin 1
Non-ATP competitive inhibitors
Benzothiazepinones
Inflammation
The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3 beta inhibitors for the treatment of ovarian cancer
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135
作者:
Gao, Yang
;
Ye, De-Yong
;
Zhou, Wei-Cheng
;
Chu, Yong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Glycogen synthase kinase 3 beta
Non-ATP competitive inhibitors
Benzothiazinones
Ovarian cancer
Antiproliferative activities
Discovery and Characterization of a Biologically Active Non-ATP-Competitive p38 MAP Kinase Inhibitor
期刊论文
2016, 卷号: 21, 期号: 3, 页码: 277-289
作者:
Wilson, Brice A. P.
;
Alam, Muhammad S.
;
Guszczynski, Tad
;
Jakob, Michal
;
Shenoy, Shilpa R.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/04
high throughput
p38
non-ATP competitive
enzyme kinetics
Screening of inhibitors of glycogen synthase kinase-3 beta from traditional Chinese medicines using enzyme-immobilized magnetic beads combined with high-performance liquid chromatography
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2015, 卷号: 1425
作者:
Li, Yunfang
;
Xu, Jia
;
Chen, Yu
;
Mei, Zhinan
;
Xiao, Yuxiu
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
GSK-3 beta
Inhibitor screening
Magnetic bead
HPLC
Traditional Chinese medicine
Non-ATP competitive inhibitor
Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 beta (GSK-3 beta)
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 61
作者:
Zhang, Peng
;
Hu, Hai-Rong
;
Bian, Shi-Hui
;
Huang, Zhao-Hui
;
Chu, Yong
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/19
GSK-3 beta
Kinase inhibitor
Non-ATP competitive
Benzothiazepinones
Selectivity
Docking
Design,synthesis and biological evaluation of benzothiazinones as novel non-ATP competitive inhibitors of glycogen synthesis kinase 3beta (GSK-3beta)
期刊论文
Chinese Journal of Medicinal Chemistry, 2013, 卷号: 23, 期号: 6, 页码: 444-452
作者:
Lu Wenbo
;
Zhang Peng
;
Huang Ke
;
Chu Yong
;
Ye Deyong
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
GSK-3beta
synthesis
benzothiazinones
glycogen synthesis kinase 3beta
non-ATP competitive inhibitor
structure-activity relationships
Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3 beta inhibitors through virtual screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 23
作者:
Zhang, Peng
;
Hu, Hai-Rong
;
Huang, Zhao-Hui
;
Lei, Jia-Yi
;
Chu, Yong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/19
GSK-3 beta
Kinase inhibitor
Virtual screening
Non-ATP competitive
Benzothiazepinones
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