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Melatonin inhibits MLL-rearranged leukemia via RBFOX3/hTERT and NF-κB/COX-2 signaling pathways. 期刊论文
Cancer letters, 2018
作者:  Tang Yan-Lai;  Sun Xi;  Huang Li-Bin;  Liu Xiao-Jian;  Qin Ge
收藏  |  浏览/下载：12/0  |  提交时间：2019/12/26
Aleukemic extramedullary T lymphoid/myeloid bilineage hematopoietic and lymphoid malignancy with progression to bilineage leukemia at relapse: A case report 期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 14, 期号: 6
作者:  Wu, Mengyao;  Li, Xiaoqiu;  Tang, Feng;  Zhu, Ping;  Ding, Tianling
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/05
Design and synthesis of benzylpiperidine inhibitors targeting the menin-mll1 interface 期刊论文
Bioorganic & medicinal chemistry letters, 2016, 卷号: 26, 期号: 18, 页码: 4472-4476
作者:  Ren, Jing;  Xu, Wei;  Tang, Le;  Su, Minbo;  Chen, Danqi
收藏  |  浏览/下载：36/0  |  提交时间：2019/05/09
Design and synthesis of benzylpiperidine inhibitors targeting the menin-MLL1 interface 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 18, 页码: 4472-4476
作者:  Ren, Jing;  Xu, Wei;  Tang, Le;  Su, Minbo;  Chen, Danqi
收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08
Modeling Human Leukemia Immunotherapy in Humanized Mice 期刊论文
EBIOMEDICINE, 2016, 卷号: 10
作者:  Xia, Jinxing;  Hu, Zheng;  Yoshihara, Satoshi;  Li, Yuying;  Jin, Chun-Hui
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05
Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation 期刊论文
Pharmacology and Therapeutics, 2015, 卷号: 151, 页码: 121-140
作者:  Liu, Ke;  Liu, Yanli;  Lau, Johnathan L;  Min, Jinrong*
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/23
Histone demethylation  DNA methylation  Inhibitor  Chemical probe  Drug discovery  LSD  lysine-specific histone demethylase  HDAC  histone deacetylase  REST  REST corepressor  DNMT  DNA methyltransferase  MAO  monoamine oxidase  AML  acute myeloid leukemia  KDM  lysine-specific demethylase  MLL  mixed lineage leukemia  FAD  flavin adenine dinucleotide  PCPA  trans-2-phenylcyclopropylamine  2,4-PDCA  2, 4-pyridinedicarboxylic acid  PHD  plant homeobox domain  SCLC  small cell lung cancer  JHDMs  JmjC-domain-containing histone demethylases  NOG  N-oxalylglycine  IOX1  5-carboxy-8-hydroxyquinoline  MDS  myelodysplastic syndrome  2-OG, 2-oxoglutarate or  α-ketoglutarate  G9a  euchromatic histone-lysine N-methyltransferase 2  CoREST complex  restin corepressor complex  SAH  S-adenosyl-l-homocysteine  l  SWI complex  ATP dependent chromatin remodeling complexes  Pan-Histone Demethylase Inhibitor  the inhibitor can simultaneously inhibit both LSDs and JHDMs  LSC colony  leukemic stem cell colony  Pan JmjC domain-containing demethylase inhibitor  the inhibitor can simultaneously inhibit all the members of JHDMs  E2F1  E2F transcription factor 1  E2F2  E2F transcription factor 2  RCC  renal cell carcinoma  
ELL Inhibits E2F1 Transcriptional Activity by Enhancing E2F1 Deacetylation via Recruitment of Histone Deacetylase 1 期刊论文
MOLECULAR AND CELLULAR BIOLOGY, 2014, 卷号: 34, 期号: 4, 页码: 765-775
作者:  Zhang, Wei;  Ji, Wei;  Liu, Xing;  Ouyang, Gang;  Xiao, Wuhan
收藏  |  浏览/下载：23/0  |  提交时间：2014/08/13
MLL-AF9-Induced Leukemogenesis Requires Coexpression of the Wild-Type Mll Allele 期刊论文
http://dx.doi.org/10.1016/j.ccr.2009.12.034, 2010
Thiel, Austin T.; Blessington, Peter; Zou, Tao; Feather, Danielle; Wu, Xinjiang; Yan, Jizhou; Zhang, Hui; Liu, Zuguo; Ernst, Patricia; Koretzky, Gary A.; Hua, Xianxin; 章慧
收藏  |  浏览/下载：4/0  |  提交时间：2013/12/12
MLL-AF9-Induced Leukemogenesis Requires Coexpression of the Wild-Type Mll Allele 期刊论文
http://dx.doi.org/10.1016/j.ccr.2009.12.034, 2010
Thiel, Austin T.; Blessington, Peter; Zou, Tao; Feather, Danielle; Wu, Xinjiang; Yan, Jizhou; Zhang, Hui; Liu, Zuguo; Ernst, Patricia; Koretzky, Gary A.; Hua, Xianxin; 张弘
收藏  |  浏览/下载：3/0  |  提交时间：2013/12/12
Elongation Factor ELL (Eleven-Nineteen Lysine-rich Leukemia) Acts as a Transcription Factor for Direct Thrombospondin-1 Regulation 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 卷号: 284, 期号: 28, 页码: 19142-19152
作者:  Zhou, Jiangang;  Feng, Xi;  Ban, Bin;  Liu, Jingxia;  Wang, Zhou
收藏  |  浏览/下载：37/0  |  提交时间：2010/10/13

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