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科研机构
复旦大学上海医学院 [8]
上海药物研究所 [4]
武汉大学 [2]
西安交通大学 [1]
中国医学科学院 北京... [1]
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期刊论文 [16]
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2022 [1]
2019 [2]
2018 [3]
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浏览/检索结果:
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The discovery of a novel series of potential ERR alpha inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo
期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 125-134
作者:
Gao, Zhipei
;
Wang, Tianxiao
;
Li, Rui
;
Du, Yongli
;
Lv, Han
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/01/18
ERR alpha
TNBC
p-Nitrobenzenesulfonamide
inverse agonist
Designing of novel ERR gamma inverse agonists by molecular modeling studies of docking and 3D-QSAR on hydroxytamoxifen derivatives
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 10, 页码: 1661-1673
作者:
Li, Rui
;
Du, Yongli
;
Shen, Jingkang
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
ERR gamma inverse agonist
Molecular docking
3D-QSAR
CoMFA
CoMSIA
Cannabinoid CB1 receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 3
作者:
He, Xiang-hu
;
Jordan, Chloe J.
;
Vemuri, Kiran
;
Bi, Guo-hua
;
Zhan, Jia
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
CB1 receptors
AM4113
SR141716A
CB1 neutral antagonist
CB1 inverse agonist
drug reward
aversion
depression
self-administration
brain-stimulation reward
From ROR gamma t Agonist to Two Types of ROR gamma t Inverse Agonists
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 2
作者:
Huang, Yafei
;
Wang, Yonghui
;
Cai, Wei
;
Tang, Ting
;
Liu, Qian
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
ROR gamma t
agonist
inverse agonist
cocrystal structure
Th17 cell differentiation
biaryl amides
Molecular Mechanism of Action of RORt Agonists and Inverse Agonists: Insights from Molecular Dynamics Simulation
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12
作者:
Sun, Nannan
;
Yuan, Congmin
;
Ma, Xiaojun
;
Wang, Yonghui
;
Gu, Xianfeng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
RORt
molecular mechanism of action (MOA)
agonist
inverse agonist
The role of ROR alpha in salivary gland lesions in patients with primary Sjogren's syndrome
期刊论文
ARTHRITIS RESEARCH & THERAPY, 2018, 卷号: 20
作者:
Weng, Xiuhong
;
Liu, Yi
;
Cui, Shun
;
Cheng, Bo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Primary Sjogren's syndrome
ROR alpha
Focus score
Th17 cells
Inverse agonist
Platelets Express Activated P2Y(12) Receptor in Patients With Diabetes Mellitus
期刊论文
CIRCULATION, 2017, 卷号: 136, 期号: 9, 页码: 817-U102
作者:
Hu, Liang
;
Chang, Lin
;
Zhang, Yan
;
Zhai, Lili
;
Zhang, Shenghui
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
antiplatelet
antithrombotic
AR-C78511
cangrelor
inverse agonist
P2Y(12)
P2Y(12) receptor antagonist
type 2 diabetes mellitus
A novel compound LingH2-10 inhibits the growth of triple negative breast cancer cells in vitro and in vivo as a selective inverse agonist of estrogen-related receptor alpha
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2017, 卷号: 93
作者:
Ning, Yang
;
Chen, Haifei
;
Du, Yongli
;
Ling, Hao
;
Zhang, Liudi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Estrogen-related receptor a
Triple negative breast cancer
Inverse agonist
Platelets Express Activated P2Y(12) Receptor in Patients With Diabetes Mellitus
期刊论文
CIRCULATION, 2017, 卷号: 136, 期号: 9
作者:
Hu, Liang
;
Chang, Lin
;
Zhang, Yan
;
Zhai, Lili
;
Zhang, Shenghui
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
antiplatelet
antithrombotic
AR-C78511
cangrelor
inverse agonist
P2Y(12)
P2Y(12) receptor antagonist
type 2 diabetes mellitus
Cannabinoid CB1 receptor inverse agonist MJ08 stimulates glucose production via hepatic sympathetic innervation in rats
期刊论文
2017, 卷号: 814, 页码: 232-239
作者:
Chen, Wei
;
Liu, Hongying
;
Guan, Hua
;
Xue, Nina
;
Wang, Lili
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Cannabinoid CB1 receptor
Inverse agonist
Hepatic glucose production
Hepatic sympathetic innervation
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