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中南大学 [4]
北京大学 [3]
武汉大学 [1]
湖南中医药大学 [1]
内容类型
期刊论文 [9]
发表日期
2016 [2]
2015 [1]
2014 [1]
2013 [2]
2003 [1]
2002 [1]
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Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*(陶怀)
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
Cloning and Genomic Characterization of a Natural Insecticidal Peptide LaIT1 with Unique DDH Structural Fold
期刊论文
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2015, 卷号: 29, 期号: 5
作者:
Chen, Jing
;
Xu, Yue
;
San, Mingkui
;
Cao, Zhijian
;
Li, Wenxin
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Inhibitor Cystine Knot
Disulfide-Directed -Hairpin
Scorpion
Genomic Organization
Huwentoxin-XVI, an analgesic, highly reversible mammalian N-type calcium channel antagonist from Chinese tarantula Ornithoctonus huwena
期刊论文
Neuropharmacology, 2014, 卷号: 79, 页码: 657-667
作者:
Deng, Meichun*
;
Luo, Xuan
;
Xiao, Yucheng
;
Sun, Zhenghua
;
Jiang, Liping
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/03
HWTX-XVI
Tarantula toxin
N-type calcium channels
Dorsal root ganglia
Rat vas deferens
Pain model
Analgesic action
HWTX
Huwentoxin
ICK
inhibitor cystine knot
Cav channel
voltage-gated calcium channel
Nav channel
voltage-gated sodium channel
DRG
dorsal root ganglion
TTX
tetrodotoxin
TTX-R
TTX-resistant
TTX-S
TTX-sensitive
IC50
median inhibitory concentration
Kv channel
voltage-gated potassium channel
HPLC
high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
Synthesis and biological characterization of synthetic analogs of Huwentoxin-IV (Mu-theraphotoxin-Hh2a), a neuronal tetrodotoxin-sensitive sodium channel inhibitor
期刊论文
Toxicon, 2013, 卷号: 71, 页码: 57-65
作者:
Deng, Meichun*
;
Luo, Xuan
;
Jiang, Liping
;
Chen, Hanchun
;
Wang, Jun
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
DRG
Dorsal root ganglion
HPLC
HWTX
HWTX-IV
High pressure liquid chromatography
Huwentoxin
IC(50)
ICK
Inhibitor cystine knot
Kv channel
MALDI-TOF
Matrix assisted laser desorption/ionization time-of-flight
Median inhibitory concentration
Mutant
Patch-clamp
Protein folding
Solid-phase peptide synthesis
TTX
TTX-R
TTX-S
TTX-resistant
TTX-sensitive
Tetrodotoxin
VGSC
Voltage-gated potassium channel
Voltage-gated sodium channel
Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana
期刊论文
Journal of Biological Chemistry, 2013, 卷号: 288, 期号: 28, 页码: 20392-20403
作者:
Liu, Zhonghua*
;
Cai, Tianfu
;
Zhu, Qi
;
Deng, Meichun
;
Li, Jiayan
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
Inhibitor Cystine Knot Motif
NMR
Nav1.7
Patch Clamp Electrophysiology
Peptides
Sodium Channels
Spider Venom
Toxins
cDNA sequence analysis of seven peptide toxins from the spider Selenocosmia huwena
期刊论文
toxicon, 2003
Diao, JB
;
Lin, Y
;
Tang, JZ
;
Liang, SP
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/12
cDNA sequence
RACE
huwentoxin
inhibitor cystine knot motif
superfamily
Selenocosmia huwena
HUWENTOXIN-I
PHONEUTRIA-NIGRIVENTER
MOLECULAR-CLONING
CYSTINE KNOT
VENOM
CHANNELS
CONOTOXINS
POTENT
MOTIF
The structure of spider toxin huwentoxin-II with unique disulfide linkage: Evidence for structural evolution
期刊论文
蛋白质科学, 2002
Shu, Q
;
Lu, SY
;
Gu, XC
;
Liang, SP
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/11
humentoxin-II
spider toxin
three-dimensional structure
disulfide bond
inhibitor cystine knot motif
disulfide-directed beta-hairpin
two-dimensional NMR
FUNNEL-WEB SPIDER
CALCIUM-CHANNEL ANTAGONIST
OMEGA-AGA-IVB
3-DIMENSIONAL STRUCTURE
SELENOCOSMIA-HUWENA
SODIUM-CHANNEL
CYSTINE KNOT
VENOM
NEUROTOXINS
POLYPEPTIDES
Three-dimensional structure of Selenocosmia huwena lectin-I (SHL-I) from the venom of the spider Selenocosmia huwena by 2D-NMR
期刊论文
journal of protein chemistry, 1999
Lu, SY
;
Liang, SP
;
Gu, XC
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
SHL-I
spider
2D NMR
inhibitor cystine knot motif
cis-proline
NUCLEAR-MAGNETIC-RESONANCE
HUWENTOXIN-I
3-DIMENSIONAL STRUCTURE
SPECTROSCOPY
HEVEIN
NMR
ASSIGNMENT
NEUROTOXIN
SEQUENCE
MOTIF
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