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科研机构
上海药物研究所 [4]
中国医学科学院 北京... [3]
北京大学 [2]
湖南大学 [2]
合肥物质科学研究院 [2]
四川大学 [1]
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期刊论文 [15]
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2021 [1]
2020 [3]
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Bruton's tyrosine kinase inhibitors in primary central nervous system lymphoma-evaluation of anti-tumor efficacy and brain distribution
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:
Yu, Haifeng
;
Kong, Haiying
;
Li, Cong
;
Dong, Xiaowu
;
Wu, Yizhe
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/08/31
Primary central nervous system lymphoma ( PCNSL)
Bruton's tyrosine kinase (BTK)
ibrutinib
zanubrutinib
tirabrutinib
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
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  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415
作者:
Lai Mengzhen
;
Song Peiran
;
Dou Dou
;
Diao Yanyan
;
Tong Linjiang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton’s tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
Inhibitory effect of resveratrol on the pharmacokinetic of ibrutinib by UPLC-MS/MS
期刊论文
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2019, 卷号: Vol.45 No.1, 页码: 27-31
作者:
Wen, Jian
;
Bao, Su-Su
;
Zhang, Bo-Wen
;
Liu, Teng-Hui
;
Ou-Yang, Qiu-Geng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/17
ibrutinib
liver microsomes
metabolism
resveratrol
Inhibitory effect of resveratrol on the pharmacokinetic of ibrutinib by UPLC–MS/MS
期刊论文
Drug Development and Industrial Pharmacy, 2019, 卷号: Vol.45 No.1, 页码: 27-31
作者:
Jian Wen
;
Su-Su Bao
;
Bo-Wen Zhang
;
Teng-Hui Liu
;
Qiu-Geng Ou-Yang
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/17
CYP3A4
ibrutinib
liver
microsomes
metabolism
resveratrol
Characterization of the binding of a novel antitumor drug ibrutinib with human serum albumin: Insights from spectroscopic, calorimetric and docking studies.
期刊论文
Journal of photochemistry and photobiology. B, Biology, 2018, 卷号: Vol.184, 页码: 18-26
作者:
Tang Bin
;
Tang Peixiao
;
He Jiawei
;
Yang Hongqin
;
Li Hui
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/02/28
Ibrutinib
Human serum albumin
Fluorescence spectroscopy
Isothermal titration calorimetry
Molecular docking
Ibrutinib versus rituximab in relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma: a randomized, open-label phase 3 study
期刊论文
CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1043-1055
作者:
Huang, Xiaojun
;
Qiu, Lugui
;
Jin, Jie
;
Zhou, Daobin
;
Chen, Xiequn
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
Asia-Pacific
chronic lymphocytic leukemia
ibrutinib
rituximab
small
lymphocytic lymphoma
Ibrutinib versus rituximab in relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma: a randomized, open-label phase 3 study
期刊论文
2018, 卷号: 7, 期号: 4, 页码: 1043-1055
作者:
Huang, Xiaojun
;
Qiu, Lugui
;
Jin, Jie
;
Zhou, Daobin
;
Chen, Xiequn
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Asia-Pacific
chronic lymphocytic leukemia
ibrutinib
rituximab
small lymphocytic lymphoma
Ibrutinib targets microRNA-21 in multiple myeloma cells by inhibiting NF-κB and STAT3
期刊论文
2018, 卷号: 40, 期号: 1, 页码: 1010428317731369
作者:
Ma Jing
;
Gong Wei
;
Liu Su
;
Li Qian
;
Guo Mengzheng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Ibrutinib
microRNA-21
multiple myeloma
nuclear factor-κB
signal transducer and activator of transcription 3
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