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Expression Patterns of the Heat Shock Protein 90 (Hsp90) Gene Suggest Its Possible Involvement in Maintaining the Dormancy of Dinoflagellate Resting Cysts
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 20, 页码: 18
作者:
Deng, Yunyan
;
Li, Fengting
;
Hu, Zhangxi
;
Yue, Caixia
;
Tang, Ying Zhong
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/01/05
dinoflagellate
dormancy
environmental cDNA library
heat shock protein 90 (Hsp90)
resting cysts
Scrippsiella trochoidea
temperature stress
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Chen, Xiang-ling
;
Liu, Peng
;
Zhu, Wei-liang
;
Lou, Li-guang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
DCZ5248
Hsp90
autophagy
lysosomal function
antitumor activity
colon cancer
Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response
期刊论文
CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 3, 页码: 344-353
作者:
Liu, Peng
;
Chen, Xiangling
;
Zhu, Jianming
;
Li, Bo
;
Chen, Zhaoqiang
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
autophagy
Hsp72
Hsp90 inhibitor
triazines
antitumor activity
The HSP90/AKT pathway may mediate artemether-induced apoptosis of Cal27 cells.
期刊论文
FEBS open bio, 2019
作者:
Ren Xiaobin
;
He Yongwen
;
Lin Ken
;
Wu Jianhua
;
Li Lei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/04
AKT
Artemether
HSP90
Tongue squamous cell carcinoma (TSCC)
apoptosis
Identification and Structure-Activity Studies of 1,3-Dibenzyl-2-aryl imidazolidines as Novel Hsp90 Inhibitors
期刊论文
MOLECULES, 2019, 卷号: 24
作者:
Liu, Yajun
;
Liu, Xiaoxia
;
Li, Lihong
;
Dai, Rui
;
Shi, Meiyun
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  |  
浏览/下载:26/0
  |  
提交时间:2019/12/02
Hsp90
imidazolidine
anti-cancer
molecule docking
virtual screening
Recent Advances in the Discovery of Novel HSP90 Inhibitors: An Update from 2014
期刊论文
Current drug targets, 2019
作者:
Xiao Yan
;
Liu Yajun
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/02
HSP90
Anticancer
Drug design
HSP90 inhibitor
HSP90β GRP94
Lead optimization
The endoplasmic reticulum (ER) chaperones BiP and Grp94 selectively associate when BiP is in the ADP conformation
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 16
作者:
Sun, Ming
;
Kotler, Judy L. M.
;
Liu, Shanshan
;
Street, Timothy O.
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
heat shock protein 90 (Hsp90)
chaperone
nucleotide
fluorescence resonance energy transfer (FRET)
fluorescence anisotropy
nuclear magnetic resonance (NMR)
allostery
BiP
Grp94
structural dynamics
Extracellular Hsp90 alpha clinically correlates with tumor malignancy and promotes migration and invasion in esophageal squamous cell carcinoma
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12, 页码: 1119-1128
作者:
Wang, Xintong
;
An, Dianzheng
;
Wang, Xinlei
;
Liu, Xiaomeng
;
Li, Baosheng
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
extracellular Hsp90 alpha
esophageal squamous cell carcinoma
lymph
node metastasis
migration
invasion
MMP-2
HSP90 inhibitor DPB induces autophagy and more effectively apoptosis in A549 cells combined with autophagy inhibitors
期刊论文
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2019, 卷号: 55, 期号: 5, 页码: 349-354
作者:
Zhao, YanChun
;
Li, Kunlun
;
Zhao, BaoXiang
;
Su, Le
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
HSP90 inhibitor
DPB
A549
Autophagy
Apoptosis
Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma
期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 3, 页码: 352-3650000000
作者:
Liu, Zhenzhen
;
Li, Hongli
;
He, Lian
;
Xiang, Yu
;
Tian, Chengsen
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
calcineurin
cancer therapy
cell signaling
click chemistry
drug screening
gene expression
glioblastoma
HSP90 inhibitor
NFAT
proteomics
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