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清华大学 [5]
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期刊论文 [29]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Myelin injury in the central nervous system and Alzheimer's disease
期刊论文
Brain Research Bulletin, 2018, 卷号: 140, 页码: 162-168
作者:
Wang, Sha-Sha
;
Zhang, Zhao
;
Zhu, Tian-Bi
;
Chu, Shi-Feng
;
He, Wen-Bin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/27
OLG
oligodendrocyte
CNS
central nervous system
SC
Schwann cell
PNS
peripheral nervous system
MBP
myelin basic protein
PLP
proteolipid protein
P0/MPZ
myelin protein zero
EAE
experimental allergic encephalomyelitis
MS
multiple sclerosis
CNP
2′ 3′-cyclic nucleotide 3′-phosphodiesterase
MAG
myelin associated glycoprotein
MOG
myelin oligodendrocyte glycoprotein
AD
Alzheimer's disease
OPC
oligodendrocyte precursor cell
NPC
neural progenitor cell
ROS
reactive oxygen species
TNF
tumour necrosis factor
AIF
apoptosis-inducing factor
IFN-γ
interferon gamma
ERK1/2
extracellular signal-regulated kinases-1 and -2
MAPK
mediators of mitogen-activated protein kinase
FGFR1/2
fibroblast growth factor receptors-1 and -2
Dock3
dedicator of cytokinesis 3
PERK
pancreatic endoplasmic reticulum kinase
GEF
guanine nucleotide exchange factor
SIRT2
sirtuin 2
NOD2
Nucleotide-binding oligomerization domain containing protein 2
RIPK2
receptor-interacting serine/threonine kinase 2
Shh
Sonic Hedgehog
NMO
neuromyelitis optica
ADEM
acute disseminated encephalomyelitis
ANHLE
acute necrotizing hemorrhagic leukoencephalitis
CPM
central pontine myelinolysis
Aβ
beta-amyloid
SP
senile plaque
NFT
neurofibrillary tangle
MRI
magnetic resonance imaging
Myelin
Oligodendrocyte
Demyelination
Neurodegenerative diseases
Alzheimer’s disease
The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive
期刊论文
ONCOTARGETS AND THERAPY, 2017, 卷号: 10
作者:
Yu, Su
;
Zhang, Yang
;
Pan, Yunjian
;
Cheng, Chao
;
Sun, Yihua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
EGFR extracellular domain mutation
non-small cell lung cancer
oncogene
drug sensitive
Structure modification and extracellular polymeric substances conversion during sewage sludge biodrying process
SCI/SSCI论文
2016
作者:
Cai L.
;
Krafft, T.
;
Chen, T. B.
;
Gao, D.
;
Wang, L.
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2017/11/09
Biodrying
Extracellular polymeric substances
Free water
Morphological
change
Sewage sludge
time-domain reflectometry
soil-water content
activated-sludge
electrical-conductivity
fluorescence excitation
regional-integration
moisture-content
dewaterability
waste
flocculation
Structure modification and extracellular polymeric substances conversion during sewage sludge biodrying process
SCI/SSCI论文
2016
作者:
Cai L.
;
Krafft, T.
;
Chen, T. B.
;
Gao, D.
;
Wang, L.
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2016/12/16
Biodrying
Extracellular polymeric substances
Free water
Morphological
change
Sewage sludge
time-domain reflectometry
soil-water content
activated-sludge
electrical-conductivity
fluorescence excitation
regional-integration
moisture-content
dewaterability
waste
flocculation
Epigenetic dynamics in immunity and autoimmunity
期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 65-74
作者:
Zhao, Ming
;
Wang, Zijun
;
Yung, Susan
;
Lu, Qianjin*
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
Epigenetic dynamics
Immune system
Autoimmune diseases
DNA methylation
Histone modifications
DNMT
DNA methyltransferase
TET
ten-eleven translocation
AID/AICDA
activation-induced cytidine deaminase
APOBEC
Apolipoprotein B mRNA editing enzyme
BER
base excision repair
MBD4
methyl-CpG binding domain protein 4
HATs
histone acetyltransferases
HDAC
histone deacetylase
HMT
histone methyltransferase
5mC
5-methylcytosine
5hmC
5-hydroxymethylcytosine
GC
germinal center
DC
dendritic cell
SHM
somatic hypermutation
CSR
class switch recombination
Blimp-1
B lymphocyte-induced maturation protein-1
Treg
regulatory T
NFAT
nuclear factor of activated T-cells
TSDR
Treg-specific demethylated region
PDCD1
programmed cell death 1
Prf1
Perforin
Gzmb
Granzyme B
CTL
cytotoxic T cell
EBF1
early B cell factor1
Pax5
Paired box protein
TSA
Trichostatin A
SLE
systemic lupus erythematosus
RA
rheumatoid arthritis
MS
multiple sclerosis
T1D
type 1 diabetes mellitus
ERK
extracellular regulated protein kinases
PBMC
peripheral blood mononuclear cell
PAD2
peptidylarginine deiminase 2
IGFBP-1
insulin-like growth factor-binding protein 1
LPS
lipopolysaccharide
Peptide signalling during the pollen tube journey and double fertilization
期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2015
Qu, Li-Jia
;
Li, Ling
;
Lan, Zijun
;
Dresselhaus, Thomas
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2017/12/03
Cysteine rich peptide (CRP)
fertilization
pollen tube
receptor-like kinase (RLK)
reproductive isolation
self-incompatibility
BRASSICA SELF-INCOMPATIBILITY
RECEPTOR KINASE LEPRK2
VITRO STYLAR MATRIX
IN-VITRO
FEMALE GAMETOPHYTE
ARABIDOPSIS-THALIANA
EXTRACELLULAR DOMAIN
SPOROPHYTIC CONTROL
FLOWERING PLANTS
MALE DETERMINANT
Functional expression of the Fc-fused extracellular domains of group II membrane proteins
期刊论文
GLYCOCONJUGATE JOURNAL, 2015, 卷号: 32, 期号: 1-2
作者:
Wu, Weicheng
;
Jin, Jing
;
Liu, Xiaojuan
;
Zhang, Yufei
;
Li, Meng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
Fc moiety
Extracellular domain
Group II membrane proteins
CLEC-2
Interferon-γ in foam cell formation and progression of atherosclerosis
期刊论文
Clinica Chimica Acta, 2015, 卷号: 441, 页码: 33-43
作者:
Xiao-HuaYu
;
JianZhang
;
Xi-LongZheng
;
Yun-HuaYang
;
Chao-KeTang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
IFN-γ
interferon-γ
IFNGR
IFN-γ receptor
VSMC
vascular smooth muscle cell
IL
interleukin
LPS
lipopolysaccharide
TNF-α
tumor necrosis factor-α
STAT
signal transducer and activator of transcription
NF-κB
nuclear factor-κB
TLR
Toll-like receptor
Tyr
tyrosine
Ser
serine
PI3Ks
phosphatidyl inositol-3 kinases
miRNAs
microRNAs
TGF-β
transforming growth factor-β
Blimp-1
B lymphocyte-induced maturation protein-1
Bcl-6
B cell lymphoma-6
NOD2
nucleotide-binding oligomerization domain 2
JAK
Janus kinase
GAS
IFN-γ activation sequences
ERK
extracellular signal-regulated kinase
PKC
protein kinase C
SOCS
suppressor of cytokine signaling
IP-10
inducible protein-10
ox-LDL
oxidized low-density lipoprotein
SRs
scavenger receptors
ACAT1
Acyl coenzyme A:cholesterol acyltransferase 1
ABCA1
ATP-binding cassette transporter A1
apo E
apolipoprotein E
MMP
matrix metalloproteinase
IFN-γ
Foam cells
Atherosclerosis
Myocardial infarction
Stroke
MicroRNAs: New players in intervertebral disc degeneration
期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 333-341
作者:
Wang, Cheng
;
Wang, Wen-Jun
;
Yan, Yi-Guo
;
Xiang, Yong-Xiao
;
Zhang, Jian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/27
IVD
intervertebral disc
NP
nucleus pulposus
AF
annulus fibrosus
CEPs
cartilaginous endplates
IDD
intervertebral disc degeneration
ECM
extracellular matrix
miRNAs
microRNAs
RNA pol
RNA polymerase
DGCR8
DiGeorge syndrome critical gene 8
Exp 5
exportin 5
TRBP
transactivating response RNA-binding protein
RISC
RNA-induced silencing complex
Ago
Argonaute
PI3K
phosphoinositide 3-kinase
MAPK
mitogen-activated protein kinase
TGF-β
transforming growth factor-β
PDGF
platelet-derived growth factor
IGF
insulin-like growth factor
EGF
epidermal growth factor
CDKI1B
cyclin-dependent kinase inhibitor 1B
TNF-α
tumor necrosis factor-α
FADD
Fas-associated death domain-containing protein
Col II
type II collagen
Col I
type I collagen
MMPs
matrix metalloproteinases
ADAMTSs
a disintegrin and metalloprotease with thrombospondin motifs
Col I
type I collagen
Col II
type II collagen
FGF2
fibroblast growth factor 2
FGFR
fibroblast growth factor receptor
IL-1β
interleukin-1β
NGF
nerve growth factor
HOXD10
homeobox D10
MiRNAs
IDD
NP cells
Apoptosis
Cell proliferation
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