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上海药物研究所 [3]
山东大学 [3]
中国医学科学院 北京... [3]
新疆理化技术研究所 [2]
中南大学 [2]
武汉大学 [2]
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期刊论文 [23]
会议论文 [3]
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HINGRL: predicting drug-disease associations with graph representation learning on heterogeneous information networks
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2022, 卷号: 23, 期号: 1, 页码: 1-15
作者:
Zhao, BW (Zhao, Bo-Wei) [1] , [2]
;
Hu, L (Hu, Lun) [2]
;
You, ZH (You, Zhu-Hong) [3] , [4]
;
Wang, L (Wang, Lei) [5]
;
Su, XR (Su, Xiao-Rui) [1] , [2]
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/05/06
drug-disease associations
prediction
heterogeneous information network
graph representation learning
drug repositioning
MGRL: Predicting Drug-Disease Associations Based on Multi-Graph Representation Learning
期刊论文
FRONTIERS IN GENETICS, 2021, 卷号: 12, 期号: 4, 页码: 1-8
作者:
Zhao, BW (Zhao, Bo-Wei)[ 1,2,3 ]
;
You, ZH (You, Zhu-Hong)[ 1,2,3 ]
;
Wong, L (Wong, Leon)[ 1,2,3 ]
;
Zhang, P (Zhang, Ping)[ 4 ]
;
Li, HY (Li, Hao-Yuan)[ 5 ]
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/05/06
drug
disease
drug repositioning
multi-graph representation learning
graph embedding
DrPOCS: Drug Repositioning Based on Projection Onto Convex Sets
期刊论文
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2019, 卷号: 16, 期号: 1
作者:
Cui, Chunfeng
;
Zhao, Xing-Ming
;
Yan, Hong
;
Qi, Liqun
;
Wang, Yin-Ying
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/05
Drug repositioning
projection onto convex sets (POCS)
matrix completion
singular value decomposition (SVD)
Prediction of drug-disease associations based on ensemble meta paths and singular value decomposition
期刊论文
BMC BIOINFORMATICS, 2019, 卷号: 20
作者:
Wu, Guangsheng
;
Liu, Juan
;
Yue, Xiang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Drug repositioning
Drug development
Meta path
Commuting matrix
Singular value decomposition
Time-Course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-Infected Human Gingival Fibroblasts
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2019, 卷号: 7
作者:
Kang, Wenyan
;
Jia, Zhilong
;
Tang, Di
;
Zhao, Xiaojing
;
Shi, Jinlong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/11
F. nucleatum
gingival fibroblasts
RNA-seq
time-course transcriptome
drug repositioning
Selecting precise reference normal tissue samples for cancer research using a deep learning approach
期刊论文
BMC MEDICAL GENOMICS, 2019, 卷号: 12
作者:
Zeng, William Z. D.
;
Glicksberg, Benjamin S.
;
Li, Yangyan
;
Chen, Bin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Drug repositioning
Deep learning
Autoencoder
Disease signatures
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:
Mao, Fei
;
Wang, Huan
;
Ni, Wei
;
Zheng, Xinyu
;
Wang, Manjiong
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
Alzheimer's disease
drug repositioning
dual-target inhibitor
AChE inhibition
PDE5 inhibition
Multi-target drug repositioning by bipartite block-wise sparse multi-task learning
会议论文
作者:
Li, Limin
;
He, Xiao
;
Borgwardt, Karsten
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/11/26
L1000
Multi-task learning
Drug repositioning
Prediction of drug-disease treatment relations based on positive and unlabeled samples
期刊论文
JOURNAL OF INTELLIGENT & FUZZY SYSTEMS, 2018, 卷号: 35, 期号: 2
作者:
Wu, Guangsheng
;
Liu, Juan
;
Min, Wenwen
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Drug repositioning
drug-disease treatment associations
unlabeled samples
machine learning
positive-unlabeled learning
From stroke to neurodegenerative diseases: The multi-target neuroprotective effects of 3-n-butylphthalide and its derivatives
期刊论文
2018, 卷号: 135, 页码: 201-211
作者:
Huang, Longjian
;
Wang, Shan
;
Ma, Fei
;
Zhang, Yong
;
Peng, Yuchen
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
3-n-Butylphthalide
Stroke
Neurodegenerative disease
Multi-target
Drug repositioning
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