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MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1 期刊论文
GASTROENTEROLOGY, 2019, 卷号: 156, 期号: 6
作者:  Li, Hui;  Li, Chia-Wei;  Li, Xiaoqiang;  Din, Qingqing;  Guo, Lei
收藏  |  浏览/下载:27/0  |  提交时间:2019/12/05
Broad targeting of triptolide to resistance and sensitization for cancer therapy 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:  Hou, Zhen-yan;  Tong, Xiao-pei;  Peng, Yong-bo;  Zhang, Bi-Kui*;  Yan, Miao*
收藏  |  浏览/下载:50/0  |  提交时间:2019/12/03
ABC  ATP-binding cassette  AKT  V-Akt murine thymoma viral oncogene homolog  ALDH1  aldehyde dehydrogenase 1  AR  androgen receptor  Bad  Bcl-2-associated death promoter  Bak  Bcl-2 homologous antagonist killer  Bax  Bcl-2-associated X protein  Bcl-2  B-cell lymphoma  Bcl-xL  Bcl-extra large  Bcl-xs  Bcl-extra short  BCRP  breast cancer resistance protein  Bid  BH3 interacting domain death agonist  Bik  Bcl-2-interacting killer  BNIP3  Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3  CAF  cancer-associated fibroblast  CAIX  carbonic anhydrase IX  cFLIP  cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein  ChIP  chromatin immunoprecipitation  CI  Combination Index  cIAP1/2  cellular IAP1/2  CML  chronic myelogenous leukemia  CSC  cancer stem cell  DISC  death-inducing signaling complex  DR  death receptor  DRI  Dose Reduction Index  ECM  extracellular matrix  EMT  epithelial-mesenchymal transition  EpCAM  epithelial cell adhesion molecule  GLUT  glucose transporter  GSK3β  glycogen synthase kinase-3β  HIF-1  hypoxia inducible factor-1  HSF1  heat shock factor 1  HSP  heat shock protein  IAP  inhibitor of apoptosis protein  JNK  c-JUN N-terminal kinase  MAPK  mitogen-activated protein kinase  Mcl-1  myeloid leukemia cell differentiation protein  MDM2  murine double minute 2  MDR  multidrug resistance  MKP  MAPK phosphatase  MRP1  multidrug resistance protein 1  NF-κB  nuclear factor-kappaB  pAkt  phosphor-Akt  PARP  poly ADP-ribose polymerase  P-gp  P-glycoprotein  PI3K-PTEN  phosphatidylinositol 3-kinase-phosphatase and tensin homolog  PKC  phosphorylated at Ser9 by protein kinase C  pp2A  protein phosphatase 2A  REST  repressor element-1 silencing transcription factor  SAR  structure-activity relationship  TAM  tumor-associated macrophage  TFIIH  transcription factor IIH  TKI  tyrosine kinase inhibitor  TM  tumor-microenvironment  TRAIL/Apo-2L  TNF-related apoptosis-inducing ligand  tRXRα  the N-terminal truncated form of the nuclear retinoid X receptor-α  TWHF  Tripterygium wilfordii Hook F  VEGF  vascular endothelial growth factor  XIAP  X-linked IAP  XPB  xerodermapigmentosum group B protein  Triptolide  Antineoplastic  Resistance  Sensitization  Mechanism  
RIPK3/Fas-Associated Death Domain Axis Regulates Pulmonary Immunopathology to Cryptococcal Infection Independent of Necroptosis 期刊论文
FRONTIERS IN IMMUNOLOGY, 2017, 卷号: 8
作者:  Fa, Zhenzong;  Xie, Qun;  Fang, Wei;  Zhang, Haibing;  Zhang, Haiwei
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05
IL-9 and Th9 cells in health and diseases—From tolerance to immunopathology 期刊论文
Cytokine and Growth Factor Reviews, 2017, 卷号: 37, 页码: 47-55
作者:  Li, Junhui;  Chen, Shuqiu;  Xiao, Xiang;  Zhao, Yong;  Ding, Wenjun
收藏  |  浏览/下载:20/0  |  提交时间:2019/12/03
TNFRSF  Tumor necrosis factor receptor super family  GITR  Glucocorticoid-induced tumor necrosis factor receptor  DR3  Death receptor 3  ILC2  Type II innate lymph cells  CNS  Conserved non-coding sequences  TSS  Transcription start site  TCR  T cell receptor  NICD  Notch intracellular domain  CIS  Cytokine-induced SH-2  SOCS  Suppressor of cytokine signaling  NIK  NF-Kb inducing kinase  TL1A  TNF-like ligand 1A  IBD  Inflammatory bowel diseases  MS  Multiple sclerosis  SLE  Systemic lupus erythematosus  RA  Rheumatic arthritis  EAE  Experimental autoimmune encephalomyelitis  MOG  Myelin oligodendrocyte glycoprotein  IRF4  IFN-regulation factor 4  mAb  Monoclonal antibody  Th9  Transcription mechanism  Immunity and immunopathology  Therapeutic purposes  
Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma 期刊论文
Gastroenterology, 2017, 卷号: 153, 期号: 5, 页码: 1429-1443.e5
作者:  Xie, Yangchun;  Zhu, Shan;  Zhong, Meizuo;  Yang, Minghua;  Sun, Xiaofan
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/03
Stimulus-dependent neuronal cell responses in SH-SY5Y neuroblastoma cells 期刊论文
MOLECULAR MEDICINE REPORTS, 2016, 卷号: 13, 期号: 3
作者:  Sun, Xiguang;  Shi, Xu;  Lu, Laijing;  Jiang, Yanfang;  Liu, Bin
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/05
CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis 期刊论文
NATURE MEDICINE, 2016
Zhang, Ting; Zhang, Yan; Cui, Mingyao; Jin, Li; Wang, Yimei; Lv, Fengxiang; Liu, Yuli; Zheng, Wen; Shang, Haibao; Zhang, Jun; Zhang, Mao; Wu, Hongkun; Guo, Jiaojiao; Zhang, Xiuqin; Hu, Xinli; Cao, Chun-Mei; Xiao, Rui-Ping
收藏  |  浏览/下载:10/0  |  提交时间:2017/12/03
CD8+/FOXP3+ratio and PD-L1 expression associated with survival in pT3N0M0 stage esophageal squamous cell cancer 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 44, 页码: 71455-71465
作者:  Zhu, Yingming;  Li, Minghuan;  Mu, Dianbin;  Kong, Li;  Zhang, Jianbo
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/16
The role of death receptor 3 in the biological behavior of hepatocellular carcinoma cells 期刊论文
Molecular Medicine Reports, 2015, 卷号: 11, 期号: 2, 页码: 797-804
作者:  Zhang, YC;  Guo, LQ;  Chen, X;  Wang, GN;  Ni, R
收藏  |  浏览/下载:5/0  |  提交时间:2016/03/29
The advantages of PD1 activating chimeric receptor (PD1-ACR) engineered lymphocytes for PDL1(+) cancer therapy 期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2015, 卷号: 7, 期号: 3
作者:  Tang, Xiaolong;  Li, Qingguo;  Zhu, Yongqiang;  Zheng, Donghui;  Dai, Jingjing
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05


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