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期刊论文 [30]
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Target Enzyme-Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 期号: 29
作者:
Ning, Jing
;
Wang, Wei
;
Ge, Guangbo
;
Chu, Peng
;
Long, Feida
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
analytical methods
cytochrome P450 3A4
enzyme
activatable probes
fluorescent probes
olecular design
Proton mediated spin state transition of cobalt heme analogs
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 2303
作者:
Zhao, Jianping
;
Peng, Qian
;
Wang, Zijian
;
Xu, Wei
;
Xiao, Hongyan
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/12/02
cobalt
cytochrome P450
heme
histidine
imidazole
imidazole derivative
iron
ligand
proton, analogs and derivatives
biocatalysis
chemistry
electron spin resonance
metabolism
oxidation reduction reaction
pH
X ray crystallography, Biocatalysis
Cobalt
Crystallography, X-Ray
Cytochrome P-450 Enzyme System
Electron Spin Resonance Spectroscopy
Heme
Histidine
Hydrogen-Ion Concentration
Imidazoles
Iron
Ligands
Oxidation-Reduction
Protons
Target Enzyme-Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 页码: 9959-9963
作者:
Ning, Jing
;
Wang, Wei
;
Ge, Guangbo
;
Chu, Peng
;
Long, Feida
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/12/02
analytical methods
cytochrome P450 3A4
enzyme
activatable probes
fluorescent probes
olecular design
Identification of new probe substrates for human CYP20A1.
期刊论文
Biological chemistry, 2019
作者:
Pradeepraj Durairaj
;
Linbing Fan
;
Sangeeta Shrestha Sharma
;
Zhao Jie
;
Matthias Bureik
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/11/21
S. pombe
cytochrome P450
enzyme inhibition
fission yeast
single nucleotide polymorphism
Functional characterization of squalene epoxidase and NADPH-cytochrome P450 reductase in Dioscorea zingiberensis
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 509, 期号: 3
作者:
Song, Wei
;
Yan, Shan
;
Li, Yi
;
Feng, Shan
;
Zhang, Jia-jiao
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2019/12/05
Dioscorea zingiberensis
Squalene epoxidase
NADPH-Cytochrome P450 reductase
Enzyme activity
Genome Sequencing Illustrates the Genetic Basis of the Pharmacological Properties of Gloeostereum incarnatum.
期刊论文
Genes, 2019, 卷号: Vol.10 No.3
作者:
Xinxin Wang
;
Jingyu Peng
;
Lei Sun
;
Gregory Bonito
;
Jie Wang
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/17
Gloeostereum incarnatum
PacBio
cytochrome P450 enzyme (CYP)
secondary metabolite
terpenoid
whole genome sequencing
Target Enzyme‐Activated Two‐Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two‐Dimensional Design Strategy
期刊论文
Angewandte Chemie (International ed. in English), 2019, 卷号: 58, 期号: 29, 页码: 9959-9963
作者:
Jing Ning
;
Wei Wang
;
Guangbo Ge
;
Peng Chu
;
Feida Long
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
analytical methods
cytochrome P450 3A4
enzyme-activatable probes
fluorescent probes
molecular design
Catalytic Function and Application of Cytochrome P450 Enzymes in Biosynthesis and Organic Synthesis
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 38, 期号: 9, 页码: 2307-2323
作者:
Jiang Yuanyuan
;
Li Shengying
收藏
  |  
浏览/下载:114/0
  |  
提交时间:2018/12/21
cytochrome P450 enzyme
biosynthesis
organic synthesis
protein engineering
substrate engineering
metabolic engineering
synthetic biology
redox partner
Co-administration with simvastatin or lovastatin alters the pharmacokinetic profile of sinomenine in rats through cytochrome P450-mediated pathways
期刊论文
LIFE SCIENCES, 2018, 卷号: Vol.209, 页码: 228-235
作者:
Wang, Yuan
;
Jin, Yi
;
Yun, Xinming
;
Wang, Meijing
;
Dai, Yue
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/26
Sinomenine
Simvastatin
Lovastatin
Drug-drug
interaction
Cytochrome
P450
enzyme
Detoxification of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by cytochrome P450 enzymes: A theoretical investigation
期刊论文
Journal of Inorganic Biochemistry, 2016, 卷号: 154, 页码: 21-28
作者:
Li, Xiao-Xi
;
Wang, Yong
;
Zheng, Qing-Chuan
;
Zhang, Hong-Xing
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2016/02/02
Cytochrome P450 enzyme
Density functional calculations
N-demethylation
Aromatic hydroxylation
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