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湖南农业大学 [5]
内容类型
期刊论文 [5]
发表日期
2016 [1]
2014 [1]
2013 [2]
2011 [1]
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The critical role of oxidative stress in the toxicity and metabolism of quinoxaline 1,4-di-N-oxides in vitro and in vivo
期刊论文
Drug metabolism reviews, 2016, 卷号: 48, 期号: 2, 页码: 159-182
作者:
Wang, Xu
;
Martinez, Maria-Aranzazu
;
Cheng, Guyue
;
Liu, Zhaoying
;
Huang, Lingli
收藏
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浏览/下载:4/0
  |  
提交时间:2019/12/23
*Quinoxaline
*antioxidants
*carbadox
*cyadox
*mequindox
*olaquindox
*oxidative stress
*quinocetone
*reactive oxygen species
Metabolic disposition and excretion of quinocetone in rats, pigs, broilers, and carp
期刊论文
Food and Chemical Toxicology, 2014, 卷号: 69, 页码: 109-119
作者:
Li, Juan
;
Huang, Lingli
;
Wang, Xu
;
Pan, Yuanhu
;
Liu, Zhaoying
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/23
QCT (Q0)
quinocetone
Q1
1-desoxyquinocetone
Q2
dideoxyquinocetone
Q3
carbonyl-reduced metabolites of 1-deoxyquinocetone
Q4
carbonyl- and double-bond-reduced metabolites of 1-deoxyquinocetone
Q5
carbonyl-reduced metabolites of dideoxyquinocetone
Q6
phenyl ring hydroxylation metabolites of carbonyl-reduced quinocetone
Q7
carbonyl-reduced quinocetone
Q8
double-bond-reduced metabolite of 4-deoxyquinocetone
Q9
phenyl ring hydroxylation metabolites of quinocetone
OLA
olaquindox
CBX
carbadox
QdNOs
quinoxaline 1,4-dioxides
MQCA
3-methylquinoxaline-2-carboxylic acid
MEQ
mequindox
QCA
quinoxalie-2-carboxylic acid
CYA
cyadox
JECFA
Joint FAO/WHO Expert Committee on Food Additives
VICH
International Cooperation on Harmonization of Technical Requirements for the Registration of Veterinary Medicinal Products
LSC
liquid scintillation counting
EIC
extracted ion chromatograms
CYP
cytochrome P450 enzyme
CBR
carbonyl reductase
H2O2
hydrogen peroxide
ROS
reactive oxygen species
Quinocetone
Radioactivity isotope tracing
Disposition
Metabolism
Excretion
Toxicology
The Metabolism of Carbadox, Olaquindox, Mequindox, Quinocetone and Cyadox: An Overview
期刊论文
Medicinal Chemistry, 2013, 卷号: 9, 期号: 8, 页码: 1017-1027
作者:
Liu, Zhao-Ying
;
Sun, Zhi-Liang*
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浏览/下载:2/0
  |  
提交时间:2019/12/23
Carbadox
Cyadox
Mequindox
Metabolism
Olaquindox
Quinocetone
Hydroxylation of quinocetone and carbadox is mediated by CYP1As in the chicken (Gallus gallus)
期刊论文
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2013, 卷号: 158, 期号: 2, 页码: 84-90
作者:
Jiannan Yang
;
Zhaoying Liu
;
Mei Li
;
Xinghui Qiu
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浏览/下载:5/0
  |  
提交时间:2019/12/23
CID
collision induced dissociation
CPR
NADPH-cytochrome P450 reductase
CYP
cytochrome P450
EIC
extract ion chromatograpy
HPLC-Q-TOF/MS
high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
TCDD
2, 3, 7, 8-tetrachlorodibenzo-p-dioxin
β-NADP +
β-nicotinamide adenine dinucleotide phosphate
Carbadox
Cyadox
CYP1A4
CYP1A5
Gallus gallus
Long-term mequindox treatment induced endocrine and reproductive toxicity via oxidative stress in male Wistar rats
期刊论文
Toxicology and Applied Pharmacology, 2011, 卷号: 252, 期号: 3, 页码: 281-288
作者:
Ihsan, Awais
;
Wang, Xu
;
Liu, Zhaoying
;
Wang, Yulian
;
Huang, Xianju
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
AR
androgen receptor
CBX
carbadox
CNS,
central nervous system
FSH
follicle stimulating hormone
GSH
reduced glutathione
H2O2
hydrogen peroxide
MDA
malondialdehyde
MEQ
mequindox
LH
lutinizing hormone
LPO
lipid peroxidation
OLA
olaquindox
QdNOs
quinoxaline 1, 4-dioxides
ROS
reactive oxygen species
SOD
superoxide dismutase
8-OHdG
8-hydroxydeoxyguanosine
StAR
steroidogenic acute regulatory protein
DNA damage
Mequindox
Oxidative stress
Quinoxaline
Rats
Testis
Testosterone
8-hydroxydeoxyguanosine (8-OHdG)
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