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CORC

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Discovery of a series of selective and cell permeable beta-secretase (BACE1) inhibitors by fragment linking with the assistance of STD-NMR 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92
作者:  Fang, Wei-Shuo;  Sun, De-yang;  Yang, Shuang;  Cheng, Chen;  Moschke, Katrin
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/05
OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. 期刊论文
BBA - Molecular Basis of Disease, 2019, 卷号: Vol.1865 No.1, 页码: 161-180
作者:  Yuan, Chunling;  Guo, Xiaoli;  Zhou, Qifan;  Du, Fangyu;  Jiang, Wei
收藏  |  浏览/下载：42/0  |  提交时间：2019/12/17
Discovery of a series of selective and cell permeable beta-secretase (BACE1) inhibitors by fragment linking with the assistance of STD-NMR 期刊论文
2019, 卷号: 92, 页码: 103253
作者:  Fang Wei-Shuo;  Sun De-Yang;  Yang Shuang;  Cheng Chen;  Moschke Katrin
收藏  |  浏览/下载：14/0  |  提交时间：2020/01/03
Iron dysregulates APP processing accompanying with sAPP alpha cellular retention and beta-secretase inhibition in rat cortical neurons 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 177-183
作者:  Chen, Yu-ting;  Chen, Wu-yan;  Huang, Xiao-tian;  Xu, Ye-chun;  Zhang, Hai-yan
收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08
Visualization of Alzheimer's Disease Related alpha-/beta-/gamma-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer 期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11, 期号: 1, 页码: 431
作者:  Wang, Xin;  Pei, Gang
收藏  |  浏览/下载：29/0  |  提交时间：2019/04/28
Defining the minimum substrate and charge recognition model of gamma-secretase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 10, 页码: 1412-1424
作者:  Yan, Yan;  Xu, Ting-Hai;  Melcher, Karsten;  Xu, H. Eric
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Antiamyloidogenic Activity of A beta 42-Binding Peptoid in Modulating Amyloid Oligomerization 期刊论文
SMALL, 2017
Zhao, Zijian; Zhu, Ling; Li, Haiyun; Cheng, Peng; Peng, Jiaxi; Yin, Yudan; Yang, Yang; Wang, Chen; Hu, Zhiyuan; Yang, Yanlian
收藏  |  浏览/下载：8/0  |  提交时间：2017/12/04
Initial Substrate Binding of gamma-Secretase: The Role of Substrate Flexibility 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 页码: 1279-1290
作者:  Li, Shu[1];  Zhang, Wan[1];  Han, Wei[1]
收藏  |  浏览/下载：9/0  |  提交时间：2019/04/24
Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression 期刊论文
Molecular Medicine Reports, 2017, 卷号: 15, 期号: 2, 页码: 712-718
作者:  Zhao, Xue-Shan;  Wu, Qi;  Peng, Juan;  Pan, Li-Hong;  Ren, Zhong
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/27
amyloidbetastructurebiologyandstructurebasedtherapeuticdevelopment 期刊论文
actapharmacologicasinica, 2017, 卷号: 38, 期号: 9, 页码: 1205
作者:  Chen Guofang;  Xu Tinghai;  Yan Yan;  Zhou Yuren;  Jiang Yi
收藏  |  浏览/下载：51/0  |  提交时间：2020/07/01

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