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Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14
作者:
Chen, Yun
;
Bai, Gang
;
Ning, Yi
;
Cai, Shi
;
Zhang, Tao
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
lnterleukin-1 receptor associated kinase 4
Imidazol1,2-6]pyridazine
Diffuse large B-cell lymphoma
Drug design
Antitumor agents
Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 2
作者:
Cui, Ying-Jie
;
Tang, Long-Qian
;
Zhang, Cheng-Mei
;
Liu, Zhao-Peng
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2019/12/11
privileged structure
pyrazoles
tubulin inhibitors
antitumor
antitumor agents
Recent Advance of Akt Inhibitors in Clinical Trials
期刊论文
CHEMISTRYSELECT, 2019, 卷号: 4, 期号: 31, 页码: 9040-9044
作者:
Guo, Kaiwen
;
Tang, Wendi
;
Zhuo, Huijun
;
Zhao, Guisen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
antitumor agents
clinical trials
inhibitors
protein kinase B
RF-assisted gadofullerene nanoparticles induces rapid tumor vascular disruption by down-expression of tumor vascular endothelial cadherin
期刊论文
BIOMATERIALS, 2018, 卷号: 163, 页码: 142-153
作者:
Li, Xue
;
Zhen, Mingming
;
Deng, Ruijun
;
Yu, Tong
;
Li, Jie
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/04/09
Antitumor Agents
Gadofullerenes
Radiofrequency
Tumor Vascular-disruption
Ve-cadherin
Biochemical and Anti-Triple Negative Metastatic Breast Tumor Cell Properties of Psammaplins
期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 11
作者:
Zhou, Yu-Dong
;
Li, Jun
;
Du, Lin
;
Mahdi, Fakhri
;
Le, Thuy P.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
psammaplins
HDAC inhibitors
HIF
VEGFA
anti-metastatic
metastatic organotropism
bone metastases
triple-negative breast cancer
metastases-specific antitumor agents
3D spheroid invasion
Proteome-Wide Identification of On- and Off-Targets of Bcl-2 Inhibitors in Native Biological Systems by Using Affinity-Based Probes (AfBPs)
期刊论文
CHEMBIOCHEM, 2018, 卷号: 19, 页码: 2312-2320
作者:
Wang, Ziqian
;
Guo, Zongwei
;
Song, Ting
;
Zhang, Xiaodong
;
He, Nianzhe
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/02
affinity-based protein profiling
antitumor agents
Bcl-2
proteins
proteomics
Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2-Based Nanoagent to Enhance Chemodynamic Therapy
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 页码: 4902-4906
作者:
Lin, Li-Sen
;
Song, Jibin
;
Song, Liang
;
Ke, Kaimei
;
Liu, Yijing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/21
imaging agents
Fenton-like reaction
antitumor agents
manganese dioxide
glutathione
pH-Controlled Drug Release of Nitrogen Doped Carbon Dots Delivering Doxorubicine for Synergetic Photo-Thermal Therapy and Chemotherapy
期刊论文
CHINESE JOURNAL OF INORGANIC CHEMISTRY, 2018, 卷号: Vol.34 No.10, 页码: 1775-1782
作者:
Shen Yu-Hua
;
Xie An-Jian
;
Yang Zheng
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/04/24
pH-controlled drug release
antitumor agents
nitrogen doped carbon dots
drug deliver
hydrothermal synthesis
photo-thermal therapy
chemotherapy
synergistic effect
Design, Synthesis, and Biological Evaluation of Pyrazoline-Based Hydroxamic Acid Derivatives as AminopeptidaseN (APN) Inhibitors
期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 5, 页码: 431-436
作者:
Cao, Jiangying
;
Zang, Jie
;
Ma, Chunhua
;
Li, Xiaoguang
;
Hou, Jinning
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
aminopeptidase N
anti-angiogenesis
antitumor agents
inhibitors
pyrazoline
Novel carbazole sulfonamide microtubule-destabilizing agents exert potent antitumor activity against esophageal squamous cell carcinoma
期刊论文
2018, 卷号: 420, 页码: 60-71
作者:
Niu, Fangfei
;
Liu, Yonghua
;
Jing, Zongpan
;
Han, Gaijing
;
Sun, Lianqi
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
Microtubule destabilizing agents
Esophageal squamous cell carcinoma
Antitumor effect
Apoptosis
Vascular disrupting agents
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