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科研机构
上海药物研究所 [4]
山东大学 [3]
中国医学科学院 北京... [3]
复旦大学上海医学院 [2]
清华大学 [1]
兰州大学 [1]
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期刊论文 [19]
发表日期
2017 [1]
2016 [2]
2015 [2]
2014 [4]
2013 [1]
2011 [2]
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A novel HIV-1 gp41 tripartite model for rational design of HIV-1 fusion inhibitors with improved antiviral activity
期刊论文
AIDS, 2017, 卷号: 31, 期号: 7
作者:
Su, Shan
;
Wang, Qian
;
Xu, Wei
;
Yu, Fei
;
Hua, Chen
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
anti-HIV drug
fusion inhibitor
six-helix bundle
tripartite model
wheel model
Design, synthesis, and biological evaluation of novel 5-Alkyl-6-Adamantylmethylpyrimidin-4(3H)-ones as HIV-1 non-nucleoside reverse-transcriptase inhibitors
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 卷号: 88, 期号: 3, 页码: 380-385
作者:
Li, Wenxin
;
Huang, Boshi
;
Kang, Dongwei
;
De Clercq, Erik
;
Daelemans, Dirk
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/16
anti-HIV-1 activity
drug design
HIV-1
NNRTIs
S-DABOs
Arylazolyl(azinyl)thioacetanilides. Part 20: Discovery of novel purinylthioacetanilides derivatives as potent HIV-1 NNRTIs via a structure-based bioisosterism approach
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 18, 页码: 4424-4433
作者:
Lu, Xueyi
;
Li, Xiao
;
Yang, Jiapei
;
Huang, Boshi
;
Kang, Dongwei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/17
HIV-1
AIDS
NNRTIs
Purinylthioacetanilide
Anti-HIV activity
Drug
design
Bioisosterism
Herb-drug interaction between an anti-HIV Chinese herbal SH formula and atazanavir in vitro and in vivo
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 162, 页码: 369-376
作者:
Cheng, Bao-Hui
;
Zhou, Xuelin
;
Wang, Yan
;
Chan, Judy Yuet-Wa
;
Lin, Huang-Quan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2015/06/29
SH formula
Atazanavir
Anti-HIV
CYP3A2
Herb-drug interaction
Herb-drug interaction between an anti-HIV Chinese herbal SH formula and atazanavir in vitro and in vivo
期刊论文
2015, 卷号: 162, 页码: 369-376
作者:
Cheng, Bao-Hui
;
Zhou, Xuelin
;
Wang, Yan
;
Chan, Judy Yuet-Wa
;
Lin, Huang-Quan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
SH formula
Atazanavir
Anti-HIV
CYP3A2
Herb-drug interaction
Anti-HIV Drug Development Through Computational Methods
期刊论文
AAPS JOURNAL, 2014, 卷号: 16, 期号: 4
作者:
Gu, Wan-Gang
;
Zhang, Xuan
;
Yuan, Jun-Fa
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/04
anti-HIV
computational methods
co-receptor
drug
enzyme
Humanized PA14 (a monoclonal CCR5 antibody) for treatment of people with HIV infection
期刊论文
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2014, 期号: 7, 页码: -
作者:
Li, L
;
Tian, JH
;
Yang, KH
;
Zhang, P
;
Jia, WQ
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2015/12/22
HIV-1 [genetics]
Anti-HIV Agents [therapeutic use]
Antibodies, Monoclonal [therapeutic use]
Antibodies, Monoclonal, Humanized
HIV Antibodies [therapeutic use]
HIV Infections [drug therapy]
RNA, Viral [blood]
Randomized Controlled Trials as Topic
Receptors, CCR5 [antagonists & inhibitors]
Adult
Humans
Optimization of the Antiviral Potency and Lipophilicity of Halogenated 2,6-Diarylpyridinamines as a Novel Class of HIV-1 NNRTIS
期刊论文
CHEMMEDCHEM, 2014, 卷号: 9, 期号: 7
作者:
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
anti-HIV activity
antiviral agents
diarylpyridinamines
drug-like properties
lipophilicity
A Novel Peptide to Disrupt the Interaction of BST-2 and Vpu
期刊论文
2014, 卷号: 102, 期号: 3, 页码: 280-287
作者:
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/13
anti-HIV-1
bone marrow stromal cell antigen 2
Vpu
drug design
Molecular modeling of human APOBEC3G to predict the binding modes of the inhibitor compounds IMB26 and IMB35
期刊论文
2013, 卷号: 3, 期号: 4, 页码: 239-244
作者:
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
Host restriction factor
APOBEC3G
HIV
Molecular modeling
Anti-HIV drug
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