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复旦大学上海医学院 [6]
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山东大学 [3]
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期刊论文 [25]
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Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
收藏
  |  
浏览/下载:269/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
A novel AR translational regulator lncRNA LBCS inhibits castration resistance of prostate cancer
期刊论文
MOLECULAR CANCER, 2019, 卷号: 18
作者:
Gu, Peng
;
Chen, Xu
;
Xie, Ruihui
;
Xie, Weibin
;
Huang, Li
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/04
Castration resistance prostate Cancer (CRPC)
lncRNA LBCS
Castration resistance
Androgen receptor (AR)
hnRNPK
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Discovery of novel 5-methyl-1H-pyrazole derivatives as potential antiprostate cancer agents: Design, synthesis, molecular modeling, and biological evaluation
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 91, 期号: 6, 页码: 1113-1124
作者:
Zhang, Daoguang
;
Asnake, Solomon
;
Zhang, Jingya
;
Olsson, Per-Erik
;
Zhao, Guisen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
androgen receptor
AR antagonist
luciferase reporter gene assay
prostate cancer
pyrazole derivative
Inhibition of androgen receptor transactivation function by adenovirus type 12 E1A undermines prostate cancer cell survival
期刊论文
PROSTATE, 2018, 卷号: 78, 期号: 15, 页码: 1140-1156
作者:
Li, Dawei
;
Tian, Guimei
;
Wang, Jia
;
Zhao, Lisa Y.
;
Co, Olivia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
androgen receptor
AR splice variants (AR-Vs)
PI3K-kinase
(PI3K)-Akt-mTOR signaling
prostate cancer gene therapy
transcriptional
regulation
Androgen receptor gene CAG repeat polymorphism and ovarian cancer risk: A meta-analysis
期刊论文
BIOSCIENCE TRENDS, 2017, 卷号: 11, 期号: 2
作者:
Deng, Yang
;
Wang, Jue
;
Wang, Ling
;
Du, Yan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Androgen receptor (AR)
CAG polymorphism
ovarian cancer risk
meta-analysis
The Long Non-Coding RNA XIST Interacted with MiR-124 to Modulate Bladder Cancer Growth, Invasion and Migration by Targeting Androgen Receptor (AR)
期刊论文
Cellular Physiology and Biochemistry, 2017, 卷号: 43, 期号: 1, 页码: 405-418
作者:
Xiong, Yaoyao
;
Wang, Long
;
Li, Yuan
;
Chen, Minfeng
;
He, Wei*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Androgen receptor (AR)
Bladder cancer
Cell proliferation
Invasion
MiR-124
Migration
Xist
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms
期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:
Peng, Mei*
;
Darko, Kwame Oteng
;
Tao, Ting
;
Huang, Yanjun
;
Su, Qiongli
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/03
AIs
aromatase inhibitors
AMPK
Adenosine Monophosphate-Activated Protein Kinase
AR
androgen
ATM
Ataxia Telangiectasia Mutated
ATP
Adenosine Triphosphate
BCSS
breast cancer specific survival
CK-MB
Creatine Kinase-MB
CREB1
cAMP Response Element-Binding Protein 1
CSC
cancer stem cell
DFS
disease-free survival
DHFU
dihydrofluorouracil
DPD
dihydropyrimidine dehydrogenase
EpCAM
Epithelial Cell Adhesion Molecule
ER
estrogen
ERCC1
excision repair cross-complementary 1
ERK
extracellular signal-regulated kinases
EZH2
enhancer of zeste homolog 2
FdUMP
fluorodeoxyuridine monophosphate
FdUTP
fluorodeoxyuridine triphosphate
FHC
ferritin heavy chain
FUTP
fluorouridine triphosphate
HbA1C
hemoglobin A1c
HER
Human Epidermal Growth Factor Receptor
HIF-1α
hypoxia-inducible factor-1α
HK
hexokinase
IGF1R
insulin growth factor 1 receptor
LDH
lactate dehydrogenase
MDA
Muscular Dystrophy Association
MMP
Matrix Metallopeptidase
MRP1
multidrug resistance-associated protein 1
mTOR
mammalian target of rapamycin
MTX
methotrexate
NCCN
National Comprehensive Cancer Network
OS
overall survival
pCR
Pathologic Complete Response
PDGFR
platelet-derived growth factor receptors
PFS
progression-free survival
PKA
protein kinase A
PR
progesterone receptor
RFS
relapse-free survival
SOD
superoxide dismutase
TAM
tamoxifen
TCA
tricarboxlic acid
TS
thymidylate synthase
Combination
Mechanisms
Metformin
Chemotherapeutic drugs
Antidepressive effects of ginsenoside Rg1 via regulation of HPA and HPG axis
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, 卷号: 92, 期号: Volume 92, 页码: 962-971
作者:
Mou, Zheng
;
Huang, Qian
;
Chu, Shi-feng
;
Zhang, Mei-Jin
;
Hu, Jin-Feng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/27
HPA
hypothalamic–pituitary–adrenal
HPG
hypothalamic–pituitary–gonadal
FST
forced swimming test
TST
tail suspension test
CUMS
chronic unpredictable mild stress
GDX
gonadectomized
GR
glucocorticoid receptor
AR
androgen receptor
Depression
Ginsenoside rg1
GR
Testosterone
AR
Steroid receptor RNA activator: Biologic function and role in disease
期刊论文
Clinica Chimica Acta, 2016, 卷号: 459, 页码: 137-146
作者:
Liu, Chan
;
Wu, Hong-Tao
;
Zhu, Neng
;
Shi, Ya-Ning
;
Liu, Zheng
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/12/03
AF-2
activation function-2
AR
androgen receptor
C/EBPα
ccaat-enhancer-binding protein α
CTCF
CCCTC-binding factor
Ddx5
DEAD box protein 5
ERα
estrogen receptor α
GR
glucocorticoid receptor
Hes1
hairy and enhancer of split-1
HP1γ
heterochromatin protein 1γ
JNK
c-Jun N-terminal kinases
lncRNA
long noncoding RNA
MyoD
myogenic differentiation 1
NANOG
homeobox protein NANOG
NR
nuclear receptor(s)
p38 MAPK
mitogen-activated protein kinase
PACT
protein kinase RNA activator
PCOS
polycystic ovary syndrome
PKR
protein kinase RNA-dependent
PPARγ
Peroxisome Proliferator-Activated Receptor gamma
PR
progesterone receptor
PRC2
polycomb repressive complex 2
preTCRα
pre T-cell antigen receptor alpha
Pus1p
pseudouridine synthesis protein
RAR
retinoic acid receptor
RBP-J
recombination signal-binding protein J
RRM
RNA recognition motif
SF-1
steroidogenic factor 1
SHARP
retinoid and thyroid hormone receptors (SMRT)/HDAC1-associated repressor protein
SLIRP
stem-loop loop-interacting RNA RNA-binding protein
SRA
Steroid receptor RNA activator
SRAP
steroid receptor RNA activator protein
SRC-1
steroid receptor coactivator-1
STR
stem-loop structure
TNFα
tumor necrosis factor α
TRBP
transactivation response RNA-binding protein
TrxG
trithorax group
SRA
Long noncoding RNAs
Nuclear receptor
Transcriptional coactivator
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