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科研机构
山东大学 [5]
中国医学科学院 北京... [4]
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上海药物研究所 [1]
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期刊论文 [20]
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Inhibition of the fibrillation of highly amyloidogenic human calcitonin by cucurbit[7]uril with improved bioactivity
期刊论文
ACTA BIOMATERIALIA, 2018, 卷号: Vol.78, 页码: 178-188
作者:
Shang, Hui
;
Zhou, Anna
;
Jiang, Jian
;
Liu, Yanpeng
;
Xie, Jing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/02/25
Human calcitonin
Amyloid beta-peptides
Cucurbit[7]uril
Inhibitor
Supramolecular chemistry
Inhibition of the fibrillation of highly amyloidogenic human calcitonin by cucurbit[7]uril with improved bioactivity
期刊论文
ACTA BIOMATERIALIA, 2018, 卷号: Vol.78, 页码: 178-188
作者:
Shang, Hui
;
Zhou, Anna
;
Jiang, Jian
;
Liu, Yanpeng
;
Xie, Jing
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/26
Human
calcitonin
Amyloid
beta-peptides
Cucurbit[7]uril
Inhibitor
Supramolecular
chemistry
Transcriptional mutagenesis mediated by 8-oxoG induces translational errors in mammalian cells
期刊论文
2018, 卷号: 115, 期号: 16, 页码: 4218-4222
作者:
Dai, Da-Peng
;
Gan, Wei
;
Hayakawa, Hiroshi
;
Zhu, Jia-Lou
;
Zhang, Xiu-Qing
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
8-oxoG
MTH1
RNA oxidization
amyloid beta peptides
beta-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling
期刊论文
2018, 卷号: 8, 页码: 969
作者:
Liu, Weiying
;
Sun, Fengxian
;
Wan, Moxin
;
Jiang, Fang
;
Bo, Xiangyu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Alzheimer's disease
HPYD
beta-amyloid peptides
APP
beta-sheet breaker peptide
Sequence-dependent interactions between model peptides and lipid bilayers
期刊论文
NUCLEAR SCIENCE AND TECHNIQUES, 2017, 卷号: 28, 期号: 9, 页码: -
作者:
Lei, HZ
;
Tian, T
;
Du, QQG
;
Hu, J
;
Zhang, Y
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2018/08/30
Atomic-force Microscopy
Protein Misfolding Diseases
Amyloid-like Peptides
Beta-sheet Tapes
Membrane Interactions
Ion Channels
Aggregation
Afm
Specificity
Interfaces
Luteolin Inhibits Fibrillary beta-Amyloid(1-40)-Induced Inflammation in a Human Blood-Brain Barrier Model by Suppressing the p38 MAPK-Mediated NF-kB Signaling Pathways
期刊论文
2017, 卷号: 22, 期号: 3
作者:
Zhang, Jun-Xia
;
Xing, Jian-Guo
;
Wang, Lin-Lin
;
Jiang, Hai-Lun
;
Guo, Shui-Long
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/04
Alzheimer's disease
amyloid-beta peptides
cyclooxygenase-2
cytokine
fibrillar amyloid-beta peptides
luteolin
mitogen-activated protein kinases
nuclear factor kB
blood-brain barrier
Interaction Dynamics in Inhibiting the Aggregation of A beta Peptides by SWCNTs: A Combined Experimental and Coarse-Grained Molecular Dynamic Simulation Study
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2016, 卷号: 7, 期号: 9
作者:
Lin, Dongdong
;
Qi, Ruxi
;
Li, Shujie
;
He, Ruoyu
;
Li, Pei
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
Alzheimer's disease
amyloid-beta peptides
carbon nanotube
interaction
inhibit
toxic oligomers
DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against A beta-induced neuronal damage via the Akt/JNK signaling pathway
期刊论文
2016, 卷号: 37, 期号: 11, 页码: 1401-1412
作者:
Zhou, Dan
;
Zhou, Wei
;
Song, Jun-ke
;
Feng, Zhang-ying
;
Yang, Ran-yao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Alzheimer's disease
amyloid beta-peptides
cholinesterase inhibitor
DL0410
learning and memory
CREB/BDNF
Akt/JNK
neuroprotection
The toxicity of beta-amyloid peptide depends on its length in transgenic Drosophila model of Alzheimer′s disease
期刊论文
Chinese Journal of Gerontology, 2015, 卷号: 35, 期号: 5, 页码: 1315-1317
作者:
Han Meng
;
Ma Pingli
;
Ye Chunyan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Alzheimer′s disease
Transgenic Drosophila
beta-amyloid peptides
Quetiapine reduces microglial number in the hippocampus of a transgenic mouse model of Alzheimer's disease
期刊论文
NEUROREPORT, 2014, 卷号: 25, 期号: 11, 页码: 870-874
作者:
Zhao Zhijun[1]
;
Luo Gang[2]
;
Liu Min[3]
;
Guo Huining[4]
;
Xue Mengzhou[5]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/23
Alzheimer's disease
beta-amyloid peptides
amyloid precursor protein/presenilin-1 double transgenic mouse model
microglia
quetiapine
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