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山东大学 [7]
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复旦大学上海医学院 [4]
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期刊论文 [47]
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Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 页码: 9
作者:
Liu Changshui
;
Zang Kun
;
Li Shihao
;
Li Fuhua
;
Ma Qingiun
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/09/22
thymidylate synthase (TS)
closed conformation
deoxyuridine monophosphate (dUMP)
thymidine monophosphate (TMP)
raltitrexed
Litopenaeus vannamei
Polymorphism rs3819102 in thymidylate synthase and environmental factors: effects on lung cancer in Chinese population
期刊论文
CURRENT PROBLEMS IN CANCER, 2019, 卷号: 43, 期号: 1
作者:
Feng, Wei
;
Guo, Xianling
;
Huang, Haidong
;
Xu, Chang
;
Li, Yutao
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/12/05
Environmental factors
Lung cancer
rs3819102 polymorphism
Smoking
Thymidylate synthase
Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway
期刊论文
CELL COMMUNICATION AND SIGNALING, 2018, 卷号: 16
作者:
Liu, Haizhou
;
Liu, Hui
;
Zhou, Zhiyi
;
Parise, Robert A.
;
Chu, Edward
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/05
Colorectal cancer
Thymidylate synthase
5-fluorouracil
Traditional Chinese herbal medicine
New Insight into the Octamer of TYMS Stabilized by Intermolecular Cys43-Disulfide
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19
作者:
Xie, Dan
;
Wang, Lulu
;
Xiao, Qi
;
Wu, Xiaoyan
;
Zhang, Lin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/02
thymidylate synthase (TYMS)
monomer
dimer
octamer
overexpression and purification
Thymidylate synthase predicts poor response to pemetrexed chemotherapy in patients with advanced breast cancer
期刊论文
ONCOLOGY LETTERS, 2018, 卷号: 16, 期号: 3, 页码: 3274-3280
作者:
Shan, Fei
;
Liu, Yu-Lin
;
Wang, Qiang
;
Shi, Yan-Long
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
advanced breast cancer
thymidylate synthase
pemetrexed
therapeutic
efficacy
correlation
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms
期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:
Peng, Mei*
;
Darko, Kwame Oteng
;
Tao, Ting
;
Huang, Yanjun
;
Su, Qiongli
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/03
AIs
aromatase inhibitors
AMPK
Adenosine Monophosphate-Activated Protein Kinase
AR
androgen
ATM
Ataxia Telangiectasia Mutated
ATP
Adenosine Triphosphate
BCSS
breast cancer specific survival
CK-MB
Creatine Kinase-MB
CREB1
cAMP Response Element-Binding Protein 1
CSC
cancer stem cell
DFS
disease-free survival
DHFU
dihydrofluorouracil
DPD
dihydropyrimidine dehydrogenase
EpCAM
Epithelial Cell Adhesion Molecule
ER
estrogen
ERCC1
excision repair cross-complementary 1
ERK
extracellular signal-regulated kinases
EZH2
enhancer of zeste homolog 2
FdUMP
fluorodeoxyuridine monophosphate
FdUTP
fluorodeoxyuridine triphosphate
FHC
ferritin heavy chain
FUTP
fluorouridine triphosphate
HbA1C
hemoglobin A1c
HER
Human Epidermal Growth Factor Receptor
HIF-1α
hypoxia-inducible factor-1α
HK
hexokinase
IGF1R
insulin growth factor 1 receptor
LDH
lactate dehydrogenase
MDA
Muscular Dystrophy Association
MMP
Matrix Metallopeptidase
MRP1
multidrug resistance-associated protein 1
mTOR
mammalian target of rapamycin
MTX
methotrexate
NCCN
National Comprehensive Cancer Network
OS
overall survival
pCR
Pathologic Complete Response
PDGFR
platelet-derived growth factor receptors
PFS
progression-free survival
PKA
protein kinase A
PR
progesterone receptor
RFS
relapse-free survival
SOD
superoxide dismutase
TAM
tamoxifen
TCA
tricarboxlic acid
TS
thymidylate synthase
Combination
Mechanisms
Metformin
Chemotherapeutic drugs
Malat1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing mir-203 and promoting thymidylate synthase expression
期刊论文
Oncotarget, 2017, 卷号: 8, 期号: 14, 页码: 22783-22799
作者:
Chen, Wei
;
Xu, Xin-Ke
;
Li, Jun-liang
;
Kong, Kuan-kei
;
Li, Hui
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/05/08
Malat1
Temozolomide
Chemoresistance
Mir-203
Thymidylate synthase
lncRNA HOTAIR Contributes to 5FU Resistance through Suppressing miR-218 and Activating NF-κB/TS Signaling in Colorectal Cancer
期刊论文
Molecular Therapy - Nucleic Acids, 2017, 卷号: 8, 页码: 356-369
作者:
Li P.
;
Zhang X.
;
Wang L.
;
Du L.
;
Yang Y.
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/12
5-fluorouracil
colorectal cancer
HOTAIR
miR-218
NF-κB
thymidylate synthase
Uridine homeostatic disorder leads to DNA damage and tumorigenesis
期刊论文
Cancer Letters, 2016, 卷号: 372, 期号: 2, 页码: 219-225
作者:
Cao, Zhe
;
Ma, Jun
;
Chen, Xinchun
;
Zhou, Boping
;
Cai, Chuan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/23
ATM
ataxia telangiectasia mutated
ATP
adenosine triphosphate
ATR
ATM-Rad3-related
BER
base excision repair
CTP
cytidine 5′-triphosphate
DAPI
4′,6-diamidino-2-phenylindole
dCDP
deoxycytidine 5′-diphosphate
dCTP
deoxycytidine 5′-triphosphate
DDR
DNA damage response
dTMP
deoxythymidylate
dTTP
deoxythymidine 5′-triphosphate
dUMP
deoxyuridylate
dUTP
2′-deoxyuridine,5′-triphosphate
FLARE assay
fragment length analysis using repair enzyme assay
mCEC
mouse colon epithelial cells
PCE
polychromatic erythrocytes
PRPP
phosphoribosyl pyrophosphate
TS
thymidylate synthase
UDG
uracil DNA glycosylase
UDP
uridine 5′-diphosphate
UK
uridine kinase
UMP
5′-monophosphate
UPase
uridine phosphorylase
UPase-2
uridine phosphorylase-2, a novel isoform
UTP
uridine 5′-triphosphate
Uridine phosphorylase
UPase knockout
Uridine homeostasis
p53
Uracil DNA damage
Carcinogenesis
An unusual UMP C-5 methylase in nucleoside antibiotic polyoxin biosynthesis
期刊论文
PROTEIN & CELL, 2016, 卷号: 7, 期号: 9
作者:
Chen, Wenqing
;
Li, Yan
;
Li, Jie
;
Wu, Lian
;
Wang, Renxiao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
polyoxin
nucleoside antibiotics
biosynthesis
UMP C5-methylase
thymidylate synthase
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