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科研机构
厦门大学 [1]
新疆理化技术研究所 [1]
中南大学 [1]
复旦大学上海医学院 [1]
上海中医药大学 [1]
内容类型
期刊论文 [5]
发表日期
2018 [1]
2017 [1]
2012 [3]
学科主题
Integrativ... [1]
Pharmacolo... [1]
Plant Scie... [1]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Toxic effects of Tripterygium wilfordii Hook F on the reproductive system of adolescent male rats
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2017, 卷号: 95
作者:
Jing, Xiaoping
;
Cheng, Weiwei
;
Guo, Sheng
;
Zou, Ya
;
Zhang, Ting
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
TWHF
Reproductive toxicity
Adolescent
Male rats
Anti-inflammatory effects and hepatotoxicity of Tripterygium-loaded solid lipid nanoparticles on adjuvant-induced arthritis in rats
期刊论文
2012
Xue, Mei
;
Jiang, Zhen-zhou
;
Wu, Tao
;
Li, Ji
;
Zhang, Liang
;
Zhao, Yan
;
Li, Xue-jun
;
Zhang, Lu-Yong
;
Yang, Shu-yu
;
杨叔禹
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2013/02/26
Tripterygium wilfordii Hook f. (TWHF)
Solid lipid nanoparticles (SLN)
Anti-inflammatory
Rheumatoid arthritis (RA)
Hepatotoxicity
Anti-inflammatory effects and hepatotoxicity of Tripterygium-loaded solid lipid nanoparticles on adjuvant-induced arthritis in rats
期刊论文
PHYTOMEDICINE, 2012, 卷号: 19, 期号: 11, 页码: 998-1006
作者:
Xue Mei
;
Jiang Zhen-zhou
;
Wu Tao
;
Li Ji
;
Zhang Liang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2013/11/07
Tripterygium wilfordii Hook f. (TWHF)
Solid lipid nanoparticles (SLN)
Anti-inflammatory
Rheumatoid arthritis (RA)
Hepatotoxicity
Transdermal microemulsion drug delivery system for impairing male reproductive toxicity and enhancing efficacy of Tripterygium Wilfordii Hook f
期刊论文
FITOTERAPIA, 2012, 卷号: 83, 期号: 4
作者:
Wang, Xiao
;
Xue, Mei
;
Cu, Jijin
;
Fang, Xiaoling
;
Sha, Xianyi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
TWHF
Microemulsion
Transdermal delivery system
Pharmacodynamics
Toxicity
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