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科研机构
大连化学物理研究所 [3]
中南大学 [2]
湖南中医药大学 [2]
清华大学 [1]
西安交通大学 [1]
山东大学 [1]
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期刊论文 [13]
会议论文 [1]
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2019 [2]
2018 [2]
2017 [1]
2016 [2]
2011 [1]
2010 [3]
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The toxicity and safety of traditional Chinese medicines: Please treat with rationality
期刊论文
BIOSCIENCE TRENDS, 2019, 卷号: 13, 期号: 5, 页码: 367-373
作者:
Cai, Pingping
;
Qiu, Hua
;
Qi, Fanghua
;
Zhang, Xiaoyi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Traditional Chinese medicines (TCMs)
Chinese patent medicines
dietary
supplements
toxicity
safety
rationality
A Computational Toxicology Approach to Screen the Hepatotoxic Ingredients in Traditional Chinese Medicines: Polygonum multiflorum Thunb as a Case Study
期刊论文
2019, 卷号: 9, 期号: 10
作者:
He Shuaibing
;
Zhang Xuelian
;
Lu Shan
;
Zhu Ting
;
Sun Guibo
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
DILI
Polygonum multiflorum Thunb
TCMs
Traditional Chinese Medicines
computational toxicology
drug-induced liver injury
hepatotoxicity
Metabolomics-based evidence of the hypoglycemic effect of Ge-Gen-Jiao-Tai-Wan in type 2 diabetic rats via UHPLC-QTOF/MS analysis
期刊论文
Journal of Ethnopharmacology, 2018, 卷号: 219, 页码: 299-318
作者:
Wang, Wenbo
;
Zhao, Linlin
;
He, Zhenyu
;
Wu, Ning
;
Li, Qiuxia
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/03
GGJTW
Ge-Gen-Jiao-Tai-Wan
T2DM
type 2 diabetes mellitus
TCMs
traditional Chinese medicines
UHPLC-QTOF/MS
ultra high performance liquid chromatography coupled with quadrupole-time-of-flight tandem mass spectrometry
BAs
bile acids
Ge-Gen-Jiao-Tai-Wan
Type 2 diabetes
Metabolomics
UHPLC-QTOF/MS
Therapeutic effects
Chinese herbal medicine
Metabolomics-based evidence of the hypoglycemic effect of Ge-Gen-Jiao-Tai-Wan in type 2 diabetic rats via UHPLC-QTOF/MS analysis
期刊论文
Journal of Ethnopharmacology, 2018, 卷号: 219, 页码: 299-318
作者:
Wang, Wenbo
;
Zhao, Linlin
;
He, Zhenyu
;
Wu, Ning
;
Li, Qiuxia
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/27
GGJTW
Ge-Gen-Jiao-Tai-Wan
T2DM
type 2 diabetes mellitus
TCMs
traditional Chinese medicines
UHPLC-QTOF/MS
ultra high performance liquid chromatography coupled with quadrupole-time-of-flight tandem mass spectrometry
BAs
bile acids
Ge-Gen-Jiao-Tai-Wan
Type 2 diabetes
Metabolomics
UHPLC-QTOF/MS
Therapeutic effects
Chinese herbal medicine
DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult
期刊论文
Toxicology Letters, 2017, 卷号: 271, 期号: Volume 271, 页码: 74-83
作者:
Zhang, Xiao-Ling
;
Yuan, Yu-He
;
Shao, Qian-Hang
;
Wang, Zhen-Zhen
;
Zhu, Cheng-Gen
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
8-OHdG
8-hydroxygluanine
ARE
antioxidant response element
GSK3β
glycogen synthase kinase 3β
HO-1
hemeoxygenase-1
LDH
lactate dehydrogenase
MDA
malondialdehyde
NQO1
NADPH quinone oxidoreductase 1
Nrf2
nuclear factor erythroid 2-related factor
PI3K
phosphoinositide-3-kinase
PD
Parkinson’s disease
ROS
reactive oxygen species
SNpc
substantia nigra pars compacta
TCMs
traditional Chinese medicines
20C
Parkinson’s disease (PD)
DJ-1
Akt
Oxidative stress
Nuclear factor erythroid 2-related factor (Nrf2)
A strategy for comprehensive identification of sequential constituents using ultra-high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometer, application study on chlorogenic acids in Flos Lonicerae Japonicae
期刊论文
Talanta, 2016, 卷号: 147, 页码: 16-27
作者:
Zhang, Jia-yu
;
Wang, Zi-jian
;
Li, Yun
;
Liu, Ying
;
Cai, Wei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
UPLC–LTQ–Orbitrap
ultra-high-performance liquid chromatography coupled with linear ion trap–Orbitrap
MIM
multiple ion monitoring
MTSF
mass spectral trees similarity filter
HRMS
high resolution mass spectrometer
CGAs
chlorogenic acids
FLJ
Flos Lonicerae Japonicae
DPIs
diagnostic product ions
TCMs
Traditional Chinese medicines
LC–MS
liquid chromatography tandem mass spectrometer
FS–PIL–DE
full scan–parent ions list–dynamic exclusion
ESI
electrospray ionization
PMFs
polymethoxylated flavonoids
CID
collision induced dissociation
SIM
selected ion monitoring
TECD
total extraction component detection
CQA
caffeoylquinic acid
DiCQA
dicaffeoylquinic acid
TriCQA
tricaffeoylquinic acid
pCoQA
p-coumaroylquinic acid
FQA
feruloylquinic acid
SQA
sinapoylquinic acid
pCoCQA
p-coumaroylcaffeoylquinic acid
CFQA
caffeoylferuloylquinic acid
pCoSQA
p-coumaroylsinapoylquinic acid
CSQA
caffeoylsinapoylquinic acid
FSQA
feruloylsinapoylquinic acid.
Chlorogenic acids
Ultra-high-performance liquid chromatography coupled with linear ion trap–Orbitrap
Flos Lonicerae Japonicae
Sequential constituents
The achievements of LC - MS/MS for the analytical phytochemicals of traditional Chinese medicines
期刊论文
Lishizhen Medicine and Materia Medica Research, 2016, 卷号: Vol.27 No.11, 页码: 2735-2737
作者:
Wu Wenjie
;
Zhou Weie
;
Zhang Yuan
;
Zhang Chuanbin
;
Li Hongna
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/31
LC - MS /MS
Traditional Chinese medicines (TCMs)
Phytochemicals
Active ingredients
Liquid chromatography - tandemm ass spectrometry(LC - MS /MS)
Quality of TCMs
Applications of HPLC/MS in the analysis of traditional Chinese medicines.
期刊论文
Journal of pharmaceutical analysis, 2011, 卷号: 1, 期号: [db:dc_citation_issue], 页码: 81-91
作者:
Li Miao
;
Hou Xiao-Fang
;
Zhang Jie
;
Wang Si-Cen
;
Fu Qiang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/10
traditional Chinese medicines (TCMs)
metabolites analysis
component analysis
HPLC/MS
pharmacokinetics
Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis
期刊论文
combinatorial chemistry & high throughput screening, 2010, 卷号: 13, 期号: 10, 页码: 855-868
作者:
Yu, Fengjiao
;
Kong, Liang
;
Zou, Hanfa
;
Lei, Xiaoyuan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2015/11/12
Traditional Chinese medicines (TCMs)
biological fingerprinting analysis
screening
bioactive components/compounds
omics
Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis
期刊论文
combinatorial chemistry & high throughput screening, 2010, 卷号: 13, 期号: 10, 页码: 855-868
作者:
Yu, Fengjiao
;
Kong, Liang
;
Zou, Hanfa
;
Lei, Xiaoyuan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2015/11/12
Traditional Chinese medicines (TCMs)
biological fingerprinting analysis
screening
bioactive components/compounds
omics
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