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Salvianolic acid inhibits the effects of high glucose on vascular endothelial dysfunction by modulating the Sirt1-eNOS pathway 期刊论文
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2019, 卷号: 33, 期号: 2
作者:  Zhai, Jinghui;  Qu, Xiaoyu;  Zhang, Yueming;  Gao, Huan;  Tao, Lina
收藏  |  浏览/下载:27/0  |  提交时间:2019/12/05
High-glucose treatment regulates biological functions of human umbilical vein endothelial cells via Sirt1/FOXO3 pathway 期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2019, 卷号: 7, 期号: 9
作者:  Chen, Yihui;  Wang, Yan;  Jiang, Yaping;  Zhang, Xiaoyan;  Sheng, Minjie
收藏  |  浏览/下载:27/0  |  提交时间:2019/12/05
Long noncoding RNAs C2dat1 enhances vascular smooth muscle cell proliferation and migration by targeting MiR-34a-5p 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 3
作者:  Wang, Hairong;  Jin, Zhili;  Pei, Tu;  Song, Wenhao;  Gong, Yao
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/05
Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK-eIF-2-CHOP pathway in the unfolded protein response 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 页码: 8614-8625
作者:  Kang, Xiaomin;  Yang, Wei;  Wang, Ruiqi;  Xie, Tianping;  Li, Huixia
收藏  |  浏览/下载:7/0  |  提交时间:2019/11/26
Exploration of the Fluorescent Properties and the Modulated Activities against Sirtuin Fluorogenic Assays of Chromenone-Derived Natural Products 期刊论文
2018, 卷号: 23, 期号: 5
作者:  Wen, Hui;  Xue, Nina;  Wu, Feng;  He, Yujun;  Zhang, Gang
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/03
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc 期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:  Yang, Shikun;  Zhao, Li;  Han, Yachun;  Liu, Yu;  Chen, Chao
收藏  |  浏览/下载:27/0  |  提交时间:2019/12/03
DN  diabetic nephropathy  ROS  reactive oxygen species  HG  high-glucose  SIRT1  sirtuin-1  Ac-H3  acetyl-histone H3  STZ  streptozotocin  AMPK  AMP-activated protein kinase  ECM  extracellular matrix  Nox2  NADPH oxidase 2  EMT  tubular epithelial-mesenchymal transition  DAPI  4′,6-diamidino-2-phenylindole 9  DHE  dihydroethidium  NDRD  non-diabetic renal disease  H&E  hematoxylin-eosin  PAS  periodic acid-Schiff  PASM  periodic acid-silver methenamine  IHC  immunohistochemistry  MDA  malondialdehyde  ChIP  chromatin immunoprecipitation  TC  total cholesterol  BUN  blood urea nitrogen  FN  fibronectin  HBA1C  glycosylated hemoglobin  Scr  serum creatinine  TG  triglyceride  Probucol  Renal injury  Diabetic nephropathy  p66Shc  
Bivalent SIRT1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 2, 页码: 180-186
作者:  Wang, Juan[1];  Zang, Wenwen[2];  Liu, Jiajia[3];  Zheng, Weiping[4]
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/24
Cyclic peptide-based potent and selective SIRT1/2 dual inhibitors harboring N-epsilon-thioacetyl-lysine 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 21, 页码: 5234-5239
作者:  Chen, Di[1];  Zheng, Weiping[2]
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/24
Antiasthmatic Effects of Resveratrol in Ovalbumin-Induced Asthma Model Mice Involved in the Upregulation of PTEN 期刊论文
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2015, 卷号: 38, 期号: 4
作者:  Chen, Guo;  Tang, JiHong;  Ni, Zhenhua;  Chen, Qingge;  Li, Zhao
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05
Novel thiourea-based sirtuin inhibitory warheads 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 16, 页码: 3319-3324
作者:  Zang, Wenwen[1];  Hao, Yujun[2];  Wang, Zhenghe[3];  Zheng, Weiping[4]
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/24


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