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厦门大学 [5]
复旦大学上海医学院 [4]
西安交通大学 [3]
中南大学 [3]
上海大学 [3]
清华大学 [2]
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期刊论文 [31]
学位论文 [2]
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2019 [2]
2018 [3]
2017 [6]
2016 [5]
2015 [2]
2014 [3]
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浏览/检索结果:
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Network Pharmacology and Reverse Molecular Docking-Based Prediction of the Molecular Targets and Pathways for Avicularin Against Cancer
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2019, 卷号: 22, 页码: 4-12
作者:
Duan, Chaohui
;
Li, Yang
;
Dong, Xiaorui
;
Xu, Weibin
;
Ma, Yingli
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/02
Avicularin
molecular mechanism
MAPK signaling pathway
network pharmacology
reverse molecular docking
molecular targets
Role of the Extracellular Signal-Regulated Kinase 1/2 Signaling Pathway in Ischemia-Reperfusion Injury
期刊论文
FRONTIERS IN PHYSIOLOGY, 2019, 卷号: 10
作者:
Kong, Tingting
;
Liu, Minghui
;
Ji, Bingyuan
;
Bai, Bo
;
Cheng, Baohua
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
ERK1/2 signaling pathway
ischemia-reperfusion injury
protective
effect
damage effect
molecular mechanism
therapeutic target
Quercetin ameliorates podocyte injury via inhibition of oxidative stress and the TGF-?1/Smad pathway in DN rats
期刊论文
RSC Advances, 2018, 卷号: 8, 页码: 35413-35421
作者:
Gao, Fanfan
;
He, Xin
;
Liang, Shanshan
;
Liu, Sixiu
;
Liu, Hua
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/11/19
Blood glucose level
Blood urea nitrogens
Diabetic nephropathy
Glomerular basement membrane
Intraperitoneal injections
Molecular mechanism
Protective effects
Signaling pathways
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Integrated bioinformatical analysis for identificating the therapeutic targets of aspirin in small cell lung cancer
期刊论文
Journal of Biomedical Informatics, 2018, 卷号: 88, 页码: 20-28
作者:
Gong, Liuyun
;
Zhang, Dan
;
Dong, Yiping
;
Lei, Yutiantian
;
Qian, Yuanjie
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/11/26
Aspirin
Integrated bioinformatical analysis
Molecular mechanism
Protein interaction
Protein targets
Signaling pathways
Small cell lung cancers
Therapeutic targets
EGFR/ERK信号通路在泡球蚴生发细胞自我更新中的作用及其分子机制
学位论文
2017, 2016
戴梦雅
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2017/06/20
泡球蚴
生发细胞
EGFR/ERK信号通路
Emsox2
自我更新
分子机制
Echinococcus multilocularis
germinative cells
EGFR/ERK signaling
Emsox2
self-renewal
molecular mechanism
Wu-Tou Decoction in Rheumatoid Arthritis: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Guo, Qingqing
;
Zheng, Kang
;
Fan, Danping
;
Zhao, Yukun
;
Li, Li
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Wu-Tou decoction
rheumatoid arthritis
mechanism of action
network pharmacology
CCR5 signaling pathway in macrophages
The link between long noncoding RNAs and depression
期刊论文
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2017, 卷号: 73
作者:
Huang, Xiao
;
Luo, Yan-li
;
Mao, Yue-shi
;
Ji, Jian-lin
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Long noncoding RNAs (lncRNAs)
Major depressive disorder (MDD)
Mechanism
Signaling pathway
Biomarker
IL-9 and Th9 cells in health and diseases—From tolerance to immunopathology
期刊论文
Cytokine and Growth Factor Reviews, 2017, 卷号: 37, 页码: 47-55
作者:
Li, Junhui
;
Chen, Shuqiu
;
Xiao, Xiang
;
Zhao, Yong
;
Ding, Wenjun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
TNFRSF
Tumor necrosis factor receptor super family
GITR
Glucocorticoid-induced tumor necrosis factor receptor
DR3
Death receptor 3
ILC2
Type II innate lymph cells
CNS
Conserved non-coding sequences
TSS
Transcription start site
TCR
T cell receptor
NICD
Notch intracellular domain
CIS
Cytokine-induced SH-2
SOCS
Suppressor of cytokine signaling
NIK
NF-Kb inducing kinase
TL1A
TNF-like ligand 1A
IBD
Inflammatory bowel diseases
MS
Multiple sclerosis
SLE
Systemic lupus erythematosus
RA
Rheumatic arthritis
EAE
Experimental autoimmune encephalomyelitis
MOG
Myelin oligodendrocyte glycoprotein
IRF4
IFN-regulation factor 4
mAb
Monoclonal antibody
Th9
Transcription mechanism
Immunity and immunopathology
Therapeutic purposes
Wu-Tou Decoction in Rheumatoid Arthritis: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation
期刊论文
Frontiers in pharmacology, 2017, 卷号: 8, 页码: 230
作者:
Guo Qingqing[1]
;
Zheng Kang[2]
;
Fan Danping[3]
;
Zhao Yukun[4]
;
Li Li[5]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/04/26
CCR5 signaling pathway in macrophages
Wu-Tou decoction
mechanism of action
network pharmacology
rheumatoid arthritis
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